• Bimala Subba Central Department of Chemistry Tribhuvan University, Kirtipur, Kathmandu, Nepal
  • Tank Raj Seling
  • Ram Chandra Kandel
  • Ganga Prasad Phuyal


Objective: The present study was designed to study and compare the antibacterial and antioxidant activity of methanol extracts of Amomum subulatum
Roxb. seeds collected from two different regions of Nepal.
Methods: Antioxidant activity was determined by 1, 1-diphenyl-2-picrylhydrazyl assay and Antibacterial activity was measured by agar well-diffusion
Results: Results showed that both sample extracts had interesting antibacterial activity against all test microorganisms and had remarkable radical
scavenging potential to be used as an antioxidant. Sample B (i.e., collected from high altitude Taplejung district) exerted comparative quit higher
antimicrobial and antioxidant activity than the Sample A (i.e., is collected from low altitude Panchthar district). However, the standard antibacterial
drug Tetracycline exhibits superior activity than the extracts.
Conclusions: The results suggest that both samples (i.e., seed extract of A. subulatum Roxb.) possess almost similar moderate antibacterial and
antioxidant activity in comparison to standards which justifies the traditional use of this plant.
Keywords: Extract, Cardamom, Activity, Medicinal plants, Seeds, Bacillus pumilus.


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How to Cite
Subba, B., T. R. Seling, R. C. Kandel, and G. P. Phuyal. “ASSESSMENT OF ANTIMICROBIAL AND ANTIOXIDANT ACTIVITIES OF AMOMUM SUBULATUM ROXB. OF NEPAL”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 10, no. 4, Apr. 2017, pp. 95-97, doi:10.22159/ajpcr.2017.v10i4.16018.
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