EVALUATION OF ANTIOXIDANT AND ANTI-INFLAMMATORY PROPERTIES OF AQUEOUS EXTRACT OF WILD MUSHROOMS COLLECTED FROM HIMACHAL PRADESH
Objective: The objective of this study is to elucidate phytochemical contents, antioxidant, and anti-inflammatory activity of wild mushrooms collected
from Himachal Pradesh.
Methods: Quantitative analysis of phytochemical constituents was carried out using standard methods while 1,1 diphenylpicrylhydrazyl nitric oxide,
hydrogen peroxide-free radical scavenging assay were used to evaluate the antioxidant properties of selected wild mushrooms. Anti-inflammatory
capacity of samples was evaluated by human red blood cell membrane stabilization and albumin denaturation inhibition method.
Results: The results obtained revealed that Pleurotus floridanus showed higher total phenol, flavonoid carotenoid, and ascorbic acid contents
of 61.13Â±2.3 mg/g, 15.2Â±1.13 mg/g, 12.42Â±0.42 Î¼g/g, 17.36Â±0.40 Î¼g/g, and 14.55Â±0.58 mg/g. All the species showed antioxidant potential, but
P. floridanus proved to be more active while Macrocybe sp. proved to be least one.
Conclusion: The mushroom species analyzed have been showed to be good source of phytoconstituents, antioxidants, and also possess antiinflammatory
properties, thus can be used in the management of oxidative stress-induced disease.
Keywords: Wild mushrooms, Scavenging effect, Total phenol, Antioxidant, Anti-inflammatory.
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