• Patchava Apparao Department of Physiotherapy, Swatantra Institute of Physiotherapy & Rehabilitation, Rajahmundry, Andhra Pradesh, India
  • Sudhakar S Department of Arthroscopy & Sports Medicine, Sri Ramachandra Medical College, Chennai, Tamil Nadu, India.
  • Ganapathi Swamy Ch Department of Community Medicine, GSL Medical College, Rajahmundry, Andhra Pradesh, India.
  • Ravi Shankar Reddy Department of Physiotherapy, King Khalid University, Abha, Saudi Arabia.


Objectives: To determine the effectiveness of knee joint stabilization exercises in minimizing articular cartilage degeneration and to examine the
effectiveness of knee joint stabilization exercises on decreasing pain, improving range of motion (ROM) and muscle strength.

Methods: About 20 volunteer subjects (age 35-65 years) with primary osteoarthritis fulfilled the inclusion criteria given the knee stabilization
exercises for 8 weeks. Pain, muscle strength, functional outcome score, and serum cartilage oligomeric matrix protein (COMP) values were measured
pre- and post-intervention using visual analog scale, dynamometer, and ELISA test. Data were analyzed using a paired t-test with Statistical Package
for the Social Sciences version 20 to find out the difference between the pre- and post-test.

Results: The results of the study have shown that significant difference between pre- and post-test values of pain, ROM, muscle strength and functional
outcome score with p<0.05, and there is statistical in significance in serum COMP value (p<0.05).
Conclusion: Stabilization exercises of knee joint were shown to be beneficial for decreasing pain, improving ROM and muscle strength, and there was
no effect on articular cartilage changes in degenerative tibiofemoral joint disease.

Keywords: Serum cartilage oligomeric matrix protein, Knee stabilization exercises, Proprioception exercises, Muscle strength.



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How to Cite
Apparao, P., S. S, G. S. Ch, and R. S. Reddy. “INFLUENCE OF STABILIZATION EXERCISES ON ARTICULAR CARTILAGE CHANGES IN DEGENERATIVE TIBIO- FEMORAL JOINT DISEASE- A PILOT STUDY”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 10, no. 4, Apr. 2017, pp. 440-4, doi:10.22159/ajpcr.2017.v10i4.17026.
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