CHRONIC HEART FAILURE CAUSES OSTEOPATHY OR IS OSTEOPATHY A FACTOR IN DEVELOPMENT OF CHRONIC HEART FAILURE?


Mariya Marushchak, Inna Krynytska, Anna Mikolenko, Yurii Andreychyn, Yaroslav Bodnar

Abstract


Objective: As their proportion rises in the aging population, cardiovascular disease and osteoporosis increasingly become significant health problems of the developed world, leading to reduced lifespan and substantial financial burdens, not the least because of complications and comorbidities associated with each disorder. This study investigates bone mineralization in patients with coronary heart disease (CHD) complicated by Stage I chronic heart failure (CHF).

Methods: The study group consisted of 41 patients of both sexes with CHF Stage I against the background of CHD that with no severe comorbidities that could have potentially caused changes in bone tissue. Bone mineral density was measured using dual-energy X-ray densitometry of lumbar region of spine and proximal right femur.

Results: Structural and functional changes in the bone of the lumbar spine were found in 75.9% of the patients with Stage I CHF caused by CHD. Osteopenia was diagnosed in 64.4% of the patients, while osteosclerotic bone changes were less frequent and found in 11.5% of the patients. 75.8% of the patients had structural and functional changes in the proximal segment of the right femur bone. In men with Stage I CHF against the background of CHD osteopenia was more often diagnosed in the proximal segment of the right femur, while in women it was found in almost equal proportion in the spine and hip.

Conclusions: In both sexes with I Stage CHF against the background of CHD were diagnosed changes in bone mineralization, with osteopenia being the prevailing diagnosis.

 


Keywords


Coronary disease, Osteopathy, Bone density.

| PDF |

References


Wójcik G, Sokołowska B, Borzęcki A. Concentration of some amino acids in blood plasma and study results of lumbosacral bone system computer tomography. Health Probl Civiliz 2015;3:5-11.

Nur’amin HW, Dwiprahasto I, Kristin E. Effectiveness of ticagrelor compared to clopidogrel in reducing the risk of major adverse cardiovascular events in patients with coronary heart disease after percutaneous coronary intervention. Int J Pharm Pharm Sci 2017;9:178-83.

Devadawson C, Jayasinghe C, Ramiah S, Kanagasing A. Amassessment of lipid profile and atherogenic indices for cardiovascular disease risk based on different fish consumption habits. Asian J Pharm Clin Res 2016;9:156-60.

Warburton DE, Nicol CW, Gatto SN, Bredin SS. Cardiovascular disease and osteoporosis: Balancing risk management. Vasc Health Risk Manag 2007;3:673-89.

Pai S, Kamath P, Sacubitril A. New paradigm in heart failure. Asian J Pharm Clin Res 2016;9:37-40.

Schulz E, Arfai K, Liu X, Sayre J, Gilsanz V. Aortic calcification and the risk of osteoporosis and fractures. J Clin Endocrinol Metab 2004;89:4246-53.

Krynytska I, Marushchak M, Zaets T, Savchenko I, Habor H. Investigation of bone mineralization in patients with coronary heart disease complicated by chronic heart failure, stage II-A. Georgian Med News 2017;43-8.

Yesil Y, Ulger Z, Halil M, Halaçli B, Yavuz BB, Yesil NK, et al. Coexistence of osteoporosis (OP) and coronary artery disease (CAD) in the elderly: It is not just a by chance event. Arch Gerontol Geriatr 2012;54:473-6.

Paccou J, Edwards MH, Ward KA, Jameson KA, Moss CL, Harvey NC, et al. Ischemic heart disease is associated with lower cortical volumetric bone mineral density of distal radius. Osteoporos Int 2015;26:1893-901.

Cummings SR, Palermo L, Browner W, Marcus R, Wallace R, Pearson J, et al. Monitoring osteoporosis therapy with bone densitometry: Misleading changes and regression to the mean. Fracture intervention trial research group. JAMA 2000;283:1318-21.

Kovalchuk LY. Problems Osteoporosis. Ternopil: Ukrmedknyha; 2002. p. 446.

Smiyan SI, Masik OM, Zhulkevych IV, Korylchuk NI, Babinets LS. Indicators of bone mineral density in healthy residents of Ukraine (Ternopil region) the results of dual energy X-ray densitometry. Post I: the female population. Probl Osteol 2000;3:9-16.

Smiyan SI, Masik OM, Zhulkevych IV. Indicators of bone mineral density of healthy men on the results of dual energy X-ray densitometry. Probl Osteol 2002;2:9-16.

Mussolino ME, Madans JH, Gillum RF. Bone mineral density and mortality in women and men: The NHANES I epidemiologic follow-up study. Ann Epidemiol 2003;13:692-7.

Trivedi DP, Khaw KT. Bone mineral density at the hip predicts mortality in elderly men. Osteoporos Int 2001;12:259-65.

Bristow MR. beta-adrenergic receptor blockade in chronic heart failure. Circulation 2000;101:558-69

Grados F, Brazier M, Kamel S, Duver S, Heurtebize N, Maamer M, et al. Effects on bone mineral density of calcium and vitamin D supplementation in elderly women with vitamin D deficiency. Joint Bone Spine 2003;70:203-8.




About this article

Title

CHRONIC HEART FAILURE CAUSES OSTEOPATHY OR IS OSTEOPATHY A FACTOR IN DEVELOPMENT OF CHRONIC HEART FAILURE?

Keywords

Coronary disease, Osteopathy, Bone density.

DOI

10.22159/ajpcr.2018.v11i1.17532

Date

01-01-2018

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 11 Issue 1 January 2018 Page: 111-115

Print ISSN

0974-2441

Online ISSN

2455-3891

Authors & Affiliations

Mariya Marushchak
Department of Functional Diagnostics and Clinical Pathophysiology, I. Horbachevsky Ternopil State Medical University, Ukraine.
Ukraine

Inna Krynytska
Department of Clinical Laboratory Diagnostics, I. Horbachevsky Ternopil State Medical University, Ukraine.
Ukraine

Anna Mikolenko
Department of Pathoanatomy, Forensic Medicine and Sectional Course, I. Horbachevsky Ternopil State Medical University, Ukraine.
Ukraine

Yurii Andreychyn
Department of Otorhinolaryngology, Ophthalmology and Neurosurgery, I. Horbachevsky Ternopil State Medical University, Ukraine.
Ukraine

Yaroslav Bodnar
Department of Pathoanatomy, Forensic Medicine and Sectional Course, I. Horbachevsky Ternopil State Medical University, Ukraine.
Ukraine


Article Tools


Email this article (Login required)
Email the author (Login required)

Refbacks

  • There are currently no refbacks.