MULTIPLE ANTIBIOTIC RESISTANCE INDEXING OF NON- FERMENTING GRAM NEGATIVE BACILLI


Bhuvaneshwari Gunasekar

Abstract


Objective: The multiple antibiotic resistance (MAR) indexing and finding Multidrug resistant (MDR) bacteria will help to indicate the origin from high risk of contamination where the antibiotics are often used. Hence this study was carried out to give the MAR index of non-fermenting Gram negative bacilli in a tertiary care hospital which would help our infection control team also.

Methods: Drug resistance was tested by Kirby bauer’s disc diffusion method. MAR index was calculated using the formula, a/b (were a= number of antibiotics to which the organism was resistant and b= total number of antibiotics to which the organism was tested).

Results: Out of 240 Gram negative non-fermenters isolated, 117 (49%) strains were greater than 0.2 of MAR index, 95(81%) was from in-patient department. 73(62%) were hospitalized for more than 3 days, 44 (38%) was from surgery department. 49(42%) was wound specimen. Out of 117 multiple antibiotic resistant isolates 99 (85%) were MDR isolates.

Conclusion: 51% prevalence of isolates >0.2 MAR index shows that the source of contamination can still be brought up down by proper surveillance and management with proper usage of  surface and skin disinfectants especially in surgery ward where the MAR index has indicated more usage of antibiotics


Keywords


Multi-drug resistance, Multiple antibiotic resistance, Non-fermenters, Antibiotic susceptibility testing, Hospital acquired the infection.

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References


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About this article

Title

MULTIPLE ANTIBIOTIC RESISTANCE INDEXING OF NON- FERMENTING GRAM NEGATIVE BACILLI

Keywords

Multi-drug resistance, Multiple antibiotic resistance, Non-fermenters, Antibiotic susceptibility testing, Hospital acquired the infection.

DOI

10.22159/ajpcr.2017.v10i6.17717

Date

01-06-2017

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 10 Issue 6 June 2017 Page: 78-80

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

69 Views | 116 Downloads

Authors & Affiliations

Bhuvaneshwari Gunasekar
Department of Microbiology, Saveetha Medical College and Hospital, Saveetha University, Thandalam, Kanchipuram, Tamil Nadu, India.
India


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