• Radhakrishnan Deventhiran Department of Biotechnology, Kurinji College of Arts and Science, Tiruchirappalli, Tamil Nadu, India
  • Kumaresan Ramanathan Department of Biochemistry, Institute of Biomedical Science, College of Health Sciences, Mekelle University (Ayder Campus), Mekelle, Ethiopia
  • Nagamurugan Nandakumar Department of Botany, Government Arts College, Melur, Madurai - 625 106, Tamil Nadu, India.


Objective: Nowadays, there is an increased incidence of infertility in Indian males due to lifestyle changes. Hence, the objective of this study isevaluating the gonadotropin releasing hormones (GnRH) level in infertile young male in Indian population.

Materials and Methods: In total, 56 patients having abnormal semen count and five control patients have been included in the study. All patientswere underwent sperm count and estimation of hormones includes GnRH such as follicle stimulating hormone (FSH), tri-iodothyronine, thyroxin,prolactin, and testosterone.

Results: The sperm concentration of infertile men was significantly lower than control. Sperm motility behaviors rapid, sluggish, and non-motilecharacters were significantly lower than control. Among GnRH, FSH has been significantly higher in infertile group than control group.

Conclusion: FSH may be considered as a marker for male infertility.

Keywords: Infertility, Gonadotropin releasing hormones, Follicle stimulating hormone, Indian male, Biomarkers, Sperm count.

Author Biography

Radhakrishnan Deventhiran, Department of Biotechnology, Kurinji College of Arts and Science, Tiruchirappalli, Tamil Nadu, India
Associate Professor in Biochemistry


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How to Cite
Deventhiran, R., K. Ramanathan, and N. Nandakumar. “PREVALANCE OF MALE INFERTILITY IN INDIA: STUDIES ON THE EFFECTS OF GONADOTROPIN RELEASING HORMONES”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 10, no. 8, Aug. 2017, pp. 208-10, doi:10.22159/ajpcr.2017.v10i8.18254.
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