Ramya Dinesh, Ramalakshmi S


 Objective: The study is to analyze the prevalence of infections caused by hepatitis B virus (HBV), and to analyze of risk factors for hepatitis B surface antigen (HBsAg) transmission among the Irula tribes of Tamil Nadu.

Methods: Serum samples were collected from 350 participants of Irula tribes from 15 different locations of Tamil Nadu. All serum samples were tested for serological markers of HBV (HBsAg) by 3rd generation enzyme-linked immunosorbent assay kit, and the data were subjected to analyze using SPSS (version 17.0) and Chi-square test to determine the risk factors of HBV among Irula tribes.

Results: In the study, HBsAg positivity was observed in a higher percentage in males 10 (8.47%) than females 9 (3.54%) and their all age groups indicate the high prevalence of HBV infection in Irula tribes. Analysis of risk factors showed that jaundice in family (JF), tattooing, series of injection, sexual promiscuity, and surgery with blood transfusion plays a major role in transmission in spread of HBV.

Conclusion: Hepatitis B is a major health problem in Irula tribes and needs to design intervention strategies among Irula tribal population.


Hepatitis B virus, Hepatitis B infection, Risk factors, Irula tribes.

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Blumberg BS. Australia antigen and the biology of hepatitis B. Science 1977;197(4298):17-25.

Nworie O, Jerry OO, Ekuma UO, Ukpabi NN, Onu EN. Studies on the seroprevalence of hepatitis B virus infection among school children in Ohaukwu, Ebonyi state, Nigeria. World Appl Sci J 2015;33(11):1767-72.

World Health Organization. World Health Statistics. Geneva: World Health Organization; 2015.

Census Organisation. Registrar General of India. India: Census Organisation; 2001.

Geethavani B, Sangamithra V, Balamuruganvelu S, Rajendran P. Seroprevalence of syphilis and leptospirosis among tribal population of Tamil Nadu and qualitative analysis of the risk factors associated with the diseases. Int J Pharm 2014;4(4):190-4.

Kalaivani V, Rajendran P, Thyagarajan SP, Rajesh PK, Hari R, Selvakumar C, et al. The seroprevalence of hepatitis B and C viruses and the associated risk factors in the Kolli hills tribal population of Tamil Nadu. Biomedicine 2001;21(1):7-13

Government of India. The Constitution of India. New Delhi: Government of India; 1949.

Gnanasekaran A, Paramasivam R, Mohan K, Daniel JC, Murugasan K, Perumal Kannabiran U, et al. Seroprevalence of certain bacterial and viral infections among the Irula tribal population of Marakkanam, Tamil Nadu state, India. Prim Health Care Res Dev 2013;14(2):185-91.

Sharma AV. Adivasis of Kodiakkarai. Chennai: Publications of the Government Museum; 1962.

Kurien T, Thyagarajan SP, Jayaseelan L, Peedicayil P, Sivaraman S, Hansdak SG, et al. Community prevalence of hepatitis B infection and modes of transmission in Tamil Nadu, India. Indian J Med Res 2005;121:670-5.

Krishnasamy N, Senthilkumar R, Sathishkumar E, Lakshmi J, Ramachandar S, Rameshkumar M. Prevalence of hepatitis B and C viral markers among the tribal population of Nilgiris, Tamil Nadu. Int J Med Res Health Sci 2015;4(3):889.

Murugan T, Rajendran P. A study on viral (HIV & HBV) and bacterial (syphilis) secually transmitted diseases (STD) among Indian gypsies population of Kanchipuram district of Tamil Nadu, India. Indian J Appl Microbiol 2011;1(2):64-7.

Rajendran P, Hussain IA, Thyagarajan SP. HBs Ag and HIV in Nilgiri tribal population of Tamil Nadu. Indian J Appl Microbiol 2001;1:37-9.

Dwibedi B, Sabat J, Ho LM, Singh SP, Sahu P, Arora R, et al. Molecular epidemiology of hepatitis B virus in primitive tribes of Odisha, eastern India. Pathog Glob Health 2014;108(8):362-8.

Joshi SH, Gorakshakar AC, Mukherjee M, Rao VR, Sathe MS, Anabhavane SM, et al. Prevalence of HBsAg carriers among some tribes of Madhya Pradesh. Indian J Med Res 1990;91:340-3.

Murhekar MV, Murhekar KM, Arankalle VA, Sehgal SC. Epidemiology of hepatitis B infection among the Nicobarese - A mongoloid tribe of the Andaman and Nicobar Islands, India. Epidemiol Infect 2002;128(3):465-71.

Nishioka SA, Gyorkos TW. Tattoos as risk factors for transmission-transmitted diseases. Int J Infect Dis 2001;5:27-34.

Chandra M, Khaja MN, Farees N, Poduri CD, Hussain MM, Aejaz Habeeb M, et al. Prevalence, risk factors and genotype distribution of HCV and HBV infection in the tribal population: A community based study in south India. Trop Gastroenterol 2003;24(4):193-5.

Long GE, Rickman LS. Infectious complications of tattoos. Clin Infect Dis 1994;18:610-9.

Alotaibi A, Khan J. Study of hepatitis B infection and its genotypes in tribal people. Asian J Pharm Clin Res 2017;10(4):51-5.

Kumar MR, Rao MS, Pulicherla KK, Ghosh M, Kumar MH, Rekha VP, et al. Studies on the distribution of hepatitis B (HBV) and human immunodeficiency virus (HIV) - Their relation to blood groups and rhesus (RH) factor in Guntur district of Andhra Pradesh, India. Asian J Pharm Clin Res 2012;16(1):109-11.

Missiriya S, Priya M, Pavithra G, Pavithran G, Priyanka K, Sandhiya R. Assess the knowledge and practice of reproductive aged tribal women on family welfare methods. Int J Pharm Pharm Sci 2017;9(1):121-4.

Ramasamy S, Balakrishnan K, Pitchappan RM. Prevalence of sickle cells in Irula, Kurumba, Paniya and Mullukurumba tribes of Nilgiris (Tamil Nadu, India). Indian J Med Res 1994;100:242-5.

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Hepatitis B virus, Hepatitis B infection, Risk factors, Irula tribes.





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Asian Journal of Pharmaceutical and Clinical Research
Vol 10 Issue 8 August 2017 Page: 100-102

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Ramya Dinesh
Department of Microbiology, Karpagam University, Karpagam Academy of Higher Education, Coimbatore - 641 021, Tamil Nadu, India.

Ramalakshmi S
Department of Microbiology, Karpagam University, Karpagam Academy of Higher Education, Coimbatore - 641 021, Tamil Nadu, India.

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