TRITERPENES FROM CERIOPS DECANDRA (GRIFF.) W. THEOB.

Judy Perez; Chien-chang Shen; Consolacion Y Ragasa

doi:10.22159/ajpcr.2017.v10i11.19461

Authors

Judy Perez Department of Chemistry, De La Salle University, Manila, Philippines. Department of Natural Sciences, College of Science and Engineering, Ateneo de Naga University, Camarines Sur, Philippines.
Chien-chang Shen Division of Chinese Medicinal Chemistry, National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taiwan.
Consolacion Y Ragasa Department of Chemistry, De La Salle University Science & Technology Complex Leandro V. Locsin Campus, Philippines

DOI:

https://doi.org/10.22159/ajpcr.2017.v10i11.19461

Keywords:

Ceriops decandra, Rhizophoraceae, Nil, Lupeol fatty acid esters, Betulonic acid, Betulin, Betulinic acid, Lupeol, Lupenone, Nil, Nil

Abstract

Â

Â Objective: To isolate and identify the chemical constituents of Ceriops decandra.

Methods: The chemical constituents of C. decandra (Griff.) W. Theob. were isolated by silica gel chromatography. The structures of the isolated compounds were identified by nuclear magnetic resonance (NMR) spectroscopy.

Results: Chemical investigation of the dichloromethane extracts of the leaves of C. decandra has led to the isolation of 3Î²-E-coumaroylbetulinic acid (1), lupeol fatty acid esters (2), betulonic acid (3), betulin (4), betulinic acid (5), lupeol (6), lupenone (7), and a mixture of 3Î²-E-feruloyllupeol (8) and 3Î²-Z-feruloyllupeol (9), and chlorophyll a (10). The structures of 1-10 were identified by comparison of their NMR data with literature data.

Conclusion: To the best of our knowledge, this is the first report on the isolation of 1-3 from C. decandra. Literature search revealed that the triterpenes isolated from C. decandra exhibited anticancer properties.

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Author Biography

Judy Perez, Department of Chemistry, De La Salle University, Manila, Philippines. Department of Natural Sciences, College of Science and Engineering, Ateneo de Naga University, Camarines Sur, Philippines.

Chemistry Department, De La Salle University

Full Professor 10

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