TRITERPENES FROM CERIOPS DECANDRA (GRIFF.) W. THEOB.


Judy Perez, Chien-chang Shen, Consolacion Y Ragasa

Abstract


 

 Objective: To isolate and identify the chemical constituents of Ceriops decandra.

Methods: The chemical constituents of C. decandra (Griff.) W. Theob. were isolated by silica gel chromatography. The structures of the isolated compounds were identified by nuclear magnetic resonance (NMR) spectroscopy.

Results: Chemical investigation of the dichloromethane extracts of the leaves of C. decandra has led to the isolation of 3β-E-coumaroylbetulinic acid (1), lupeol fatty acid esters (2), betulonic acid (3), betulin (4), betulinic acid (5), lupeol (6), lupenone (7), and a mixture of 3β-E-feruloyllupeol (8) and 3β-Z-feruloyllupeol (9), and chlorophyll a (10). The structures of 1-10 were identified by comparison of their NMR data with literature data.

Conclusion: To the best of our knowledge, this is the first report on the isolation of 1-3 from C. decandra. Literature search revealed that the triterpenes isolated from C. decandra exhibited anticancer properties.


Keywords


Ceriops decandra, Rhizophoraceae, 3β-E-coumaroylbetulinic acid, Lupeol fatty acid esters, Betulonic acid, Betulin, Betulinic acid, Lupeol, Lupenone, 3β-E-feruloyllupeol, 3β-Z-feruloyllupeol.

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About this article

Title

TRITERPENES FROM CERIOPS DECANDRA (GRIFF.) W. THEOB.

Keywords

Ceriops decandra, Rhizophoraceae, 3β-E-coumaroylbetulinic acid, Lupeol fatty acid esters, Betulonic acid, Betulin, Betulinic acid, Lupeol, Lupenone, 3β-E-feruloyllupeol, 3β-Z-feruloyllupeol.

DOI

10.22159/ajpcr.2017.v10i11.19461

Date

01-11-2017

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 10 Issue 11 November 2017 Page: 244-246

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

28 Views | 43 Downloads

Authors & Affiliations

Judy Perez
Department of Chemistry, De La Salle University, Manila, Philippines. Department of Natural Sciences, College of Science and Engineering, Ateneo de Naga University, Camarines Sur, Philippines.
Philippines

Chien-chang Shen
Division of Chinese Medicinal Chemistry, National Research Institute of Chinese Medicine, Ministry of Health and Welfare, Taiwan.
Taiwan, Republic of China

Consolacion Y Ragasa
Department of Chemistry, De La Salle University Science & Technology Complex Leandro V. Locsin Campus, Philippines
Philippines


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