ETHNOBOTANICAL, PHYTOCHEMICAL, AND PHARMACOLOGICAL PROPERTIES OF NEPENTHES SPECIES: A REVIEW


Shuaibu Babaji Sanusi, Mohd Fadzelly Abu Bakar, Maryati Mohamed, Siti Fatimah Sabran, Muhammad Murtala Mainasara

Abstract


The genus Nepenthes (Nepenthaceae) has been utilized in folk medicine for a long time in India and Southeast Asia countries. They are used in the treatment of leprosy, cholera, night blindness, gastrointestinal discomfort, dysentery, stomachache, and bed-wetting among others. This review highlights the ethnobotanical uses, phytochemicals, and pharmacological activities of both crude extracts and pure bioactive compounds of Nepenthes spp. The phytochemical compounds isolated from Nepenthes species include flavonoids, terpenoids, tannins, alkaloids, and steroids among other phytochemicals. A wide range of pharmacological activities was exhibited by the crude extracts and pure bioactive components such as antibacterial, antifungal, antimalarial antioxidant, antidiabetic, antiosteoporotic, anti-inflammatory, cytotoxicity, and hypolipidemic activities. This review revealed that many active compounds are present in Nepenthes spp. However, many pharmacological screenings such as anticancer, antiviral, wound healing, antihelminthic, antidiarrheal properties, among others have not been carried out yet. Therefore, more biological investigations and phytochemical screenings are required to fully explore the genus Nepenthes which may lead to development of new therapeutic agents.  


Keywords


Nepenthes species, Ethnobotanical, Phytochemistry, Pharmacological activities.

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About this article

Title

ETHNOBOTANICAL, PHYTOCHEMICAL, AND PHARMACOLOGICAL PROPERTIES OF NEPENTHES SPECIES: A REVIEW

Topics

Phytochemistry; phytomedicine' natural products

Keywords

Nepenthes species, Ethnobotanical, Phytochemistry, Pharmacological activities.

DOI

10.22159/ajpcr.2017.v10i11.20050

Date

01-11-2017

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 10 Issue 11 November 2017 Page: 16-19

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

64 Views | 119 Downloads

Authors & Affiliations

Shuaibu Babaji Sanusi
Centre of Research for Sustainable Uses of Natural Resources (CoR-SUNR), Faculty of Science, Technology and Human Development, Universiti Tun Hussein Onn Malaysia (UTHM), 86400 Parit Raja, Batu Pahat, Johor, Malaysia
Malaysia

Mohd Fadzelly Abu Bakar
Centre of Research for Sustainable Uses of Natural Resources (CoR-SUNR), Faculty of Science, Technology and Human Development, Universiti Tun Hussein Onn Malaysia (UTHM), 86400 Parit Raja, Batu Pahat, Johor, Malaysia
Malaysia

Maryati Mohamed
Centre of Research for Sustainable Uses of Natural Resources (CoR-SUNR), Faculty of Science, Technology and Human Development, Universiti Tun Hussein Onn Malaysia (UTHM), 86400 Parit Raja, Batu Pahat, Johor, Malaysia
Malaysia

Siti Fatimah Sabran
Centre of Research for Sustainable Uses of Natural Resources (CoR-SUNR), Faculty of Science, Technology and Human Development, Universiti Tun Hussein Onn Malaysia (UTHM), 86400 Parit Raja, Batu Pahat, Johor, Malaysia
Malaysia

Muhammad Murtala Mainasara
Centre of Research for Sustainable Uses of Natural Resources (CoR-SUNR), Faculty of Science, Technology and Human Development, Universiti Tun Hussein Onn Malaysia (UTHM), 86400 Parit Raja, Batu Pahat, Johor, Malaysia
Malaysia


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