COMPARATIVE ASSESSMENT OF THERAPEUTIC POTENTIAL OF VACHADI AND HINGWADI GHTRITA IN PATIENTS OF DEPRESSION


Pawar Madhuri, Wele Asmita

Abstract


 Objective: Present exploratory clinical study dealt with comparative assessment of therapeutic effect of medicated ghee formulations i.e. Vachadi [VG] and Hingwadi Ghrita [HG] in patients of mild to moderate depression.

Methods: Open label nonrandomized standard controlled clinical trial was carried out. Using Hamilton scale test total twelve patients of mild to moderate depression were grouped in two groups[A and B]. Patients of group A and group B received HG and VG along with standard antidepressants respectively for sixty days. Pre, mid and post HAMD scores of both group patients were recorded and compared. Data was analyzed with Friedman and Mann Whitney statistical test.

Results: Statistical analysis showed a significant gradual change in HAMD values for both study groups after sixty days of treatment [P< 0.05]. However, when pre and post HAMD scores of both groups are statistically analyzed, Hingwadi Ghrita demonstrated significant positive result in reduction of HAMD scores compared to Vachadi Ghrita [P=0.003]. Beneficial effects on patients appetite, bowel movement was seen for both group patients.

Conclusion: Thus it is concluded that along with antidepressants Hingwadi Ghrita would be the better choice as an adjuvant drug than Vachadi Ghrita for mild to moderate depression patients. More studies with larger number should be done to validate this result.


Keywords


: Depression, Unmad-Vishad, Hingwadi Ghrita, Vachadi Ghrita, medicated ghee, Hamilton scale

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About this article

Title

COMPARATIVE ASSESSMENT OF THERAPEUTIC POTENTIAL OF VACHADI AND HINGWADI GHTRITA IN PATIENTS OF DEPRESSION

Keywords

: Depression, Unmad-Vishad, Hingwadi Ghrita, Vachadi Ghrita, medicated ghee, Hamilton scale

DOI

10.22159/ajpcr.2017.v10i12.20263

Date

01-12-2017

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 10 Issue 12 December 2017 Page: 59-62

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

22 Views | 49 Downloads

Authors & Affiliations

Pawar Madhuri
Department of Ayurvedic pharmaceutics and pharmacology, BVDU, college of Ayurved,Pune,
India

Wele Asmita
Department of Ayurvedic pharmaceutics and pharmacology, BVDU, college of Ayurved,Pune,
India


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