COMPARISON OF PHYSIOLOGICAL PARAMETERS IN CHILDREN UNDERGOING DENTAL TREATMENT UNDER GENERAL ANESTHESIA WITH PROPOFOL AND SEVOFLURANE - A RETROSPECTIVE COHORT STUDY

  • Lavanya Govindaraju Department of Pediatric and Preventive Dentistry, Saveetha Dental College, Chennai, Tamil Nadu, India.
  • Deepa Gurunathan Department of Pediatric and Preventive Dentistry, Saveetha Dental College, Chennai, Tamil Nadu, India.
  • Navaneetha Krishnan Department of Anesthesiology, Saveetha Medical College, Chennai, Tamil Nadu, India.

Abstract

 

 Objective: The present study was conducted to evaluate the effect of these drugs on the blood pressure (BP) and pulse rate during induction of anesthesia in children undergoing full mouth rehabilitation.

Methods: Data were collected from the records maintained for the children <6 years who underwent full mouth rehabilitation under general anesthesia (GA). The drugs used for induction, the changes seen in the BP, pulse rate were recorded. Statistical analysis was done using Mann–Whitney test with p<0.05, significant.

Results: Of 64 children treated under GA, 31 children were induced with propofol and by sevoflurane in the remaining 33 children. The induction time with 2 mg/kg dosage of propofol was approximately 12 seconds while it was variable with 8% sevoflurane. The mean systolic and diastolic BP and pulse rate were found to be within the normal levels under both the drugs.

Conclusion: In children, sevoflurane and propofol can be safely used for inducing anaesthesia.

Keywords: Blood pressure, Children, Induction, Propofol, Pulse rate, Sevoflurane.

References

1. Cote CJ, Wilson S. Guidelines for monitoring and management of pediatric patients before, during and after sedation for diagnostic and therapeutic procedures: An update 2016. Pediatr 2016;138:e1-31.
2. Alwardt CM, Redford D, Larson DF. General anesthesia in cardiac surgery: A review of drugs and practices. J Extra Corpor Technol 2005;37:227-35.
3. Yakubu JM, Abdullahi A, Bhagavandas M, Onifade KI. Effect of time influence on physiological parameters following ketamine and diazepam administration in cats. Int J Pharm Pharm Sci 2015;7:363-6.
4. Akioye AA, Ojiaka HN, Samuel ES. Xylazine-ketamine anaesthesia; comparitive studies in male and female cane rats. Int J Pharm Pharm Sci 2017;9:52-5.
5. Tagliente TM. Pharmacoeconomics of propofol in anesthesia. Am J Health Syst Pharm 1997;54:1953-62.
6. Kim SO, Kim YJ, Hyun HK, Koo YS, Shin TJ. Deep sedation with sevoflurane inhalation via a nasal hood for brief dental procedures in pediatric patients. Pediatr Emerg Care 2013;29:926-8.
7. Hosey MT. Propofol intravenous consious sedation for anxious children in a specialist paediatric dentistry unit. Int J Paediatric Dent 2004;14:2-8.
8. Jellish WS, Lien CA, Fontenot HJ, Hall R. The comparative effects of sevoflurane versus propofol in the induction and maintenance of anesthesia in adult patients. Anesth Analg 1996;82:479-85.
9. Lerman J. Surgical and patient factors involved in postoperative nausea and vomiting. Br J Anaesth 1992;69 7 Suppl 1:24S-32.
10. Joo HS, Perks WJ. Sevoflurane versus propofol for anesthetic induction: A meta-analysis. Anesth Analg 2000;91:213-9.
Statistics
218 Views | 282 Downloads
How to Cite
Govindaraju, L., D. Gurunathan, and N. Krishnan. “COMPARISON OF PHYSIOLOGICAL PARAMETERS IN CHILDREN UNDERGOING DENTAL TREATMENT UNDER GENERAL ANESTHESIA WITH PROPOFOL AND SEVOFLURANE - A RETROSPECTIVE COHORT STUDY”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 10, no. 11, Nov. 2017, pp. 157-8, doi:10.22159/ajpcr.2017.v10i11.20599.
Section
Original Article(s)