A PROSPECTIVE EVALUATION OF CAUSES AND TREATMENT OF INFERTILITY IN A TERTIARY CARE HOSPITAL, ERODE


Amala Baby, Anila A Varghese, Cindy Jose, Krishnaveni Kandasamy, Shanmuga Sundaram Rajagopal

Abstract


 Objective: Infertility has a serious impact on the psychosocial well-being of women in the developing world. The objective of the study was to evaluate the causes and treatment pattern of infertility patients in a tertiary care hospital.

Methods: The prospective observational study focused on the sociodemographic properties of infertile patients, causes of infertility, and various treatments carried out in a tertiary care hospital, Erode, Tamil Nadu.

Results: Of 200 cases, the majority was due to female factor (45.5%), followed by male factors (26%), both gender factors (25.5%), and unexplained etiology (6%). It was observed that major causes of male infertility (MI) were oligoasthenoteratozoospermia (OATS - 48.42%), followed by asthenozoospermia (17.89%), azoospermia (11.57%), erectile dysfunction (7.36%), oligoasthenozoospermia (5.26%), varicocele (3.15%), oligospermia (2.10%), necrozoospermia (2.10%), asthenoteratozoospermia (1.05%), and asthenozoospermia+erectile dysfunction (1.05%). In cases of female infertility (FI), the pattern of causes was polycystic ovarian disease (PCOD) (29.6%), followed by tubular block (13.23%), cyst (6.66%), hypothyroidism (4.44%), endometriosis (4.44%), hormonal problems (4.44%), fibroid (3.7%), fibroid+cyst (3.7%), premature ovarian failure (2.96%), thin endometrium (2.96%), multifollicularovary (2.96%), PCOD+hormonalproblems (2.96%), and hypothyroidism+hormonal problems (2.22%). Intrauterine insemination was the most commonly assisted reproductive technology employed, followed by in vitro fertilization and intracytoplasmic sperm injection. Of 200 infertile couples, 57 (28.5%) were unable to conceive within 6 months and 72 (36%) after 6 months following first consultation, 44 (22%) defaulted/lost follow-up/were still under consultation, 13 (6.5%) conceived with the help of assisted reproductive treatment, 10 (5%) conceived with the help of drug treatment, anddd 4 (2%) had spontaneous pregnancy.

Conclusion: The major cause of infertility was found to be PCOD in females and OATS in males. The most commonly prescribed drugs were antioxidants for males and progesterone for females.


Keywords


Infertility, Polycystic ovarian disease, Oligoasthenoteratozoospermia.

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About this article

Title

A PROSPECTIVE EVALUATION OF CAUSES AND TREATMENT OF INFERTILITY IN A TERTIARY CARE HOSPITAL, ERODE

Keywords

Infertility, Polycystic ovarian disease, Oligoasthenoteratozoospermia.

DOI

10.22159/ajpcr.2018.v11i2.22108

Date

01-02-2018

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 11 Issue 2 February 2018 Page: 149-153

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

19 Views | 36 Downloads

Authors & Affiliations

Amala Baby
Department of Pharmacy Practice, J.K.K Nattraja College of Pharmacy, Kumarapalayam - 638 183, Namakkal, Tamil Nadu, India
India

Anila A Varghese
Department of Pharmacy Practice, J.K.K Nattraja College of Pharmacy, Kumarapalayam - 638 183, Namakkal, Tamil Nadu, India
India

Cindy Jose
Department of Pharmacy Practice, J.K.K Nattraja College of Pharmacy, Kumarapalayam - 638 183, Namakkal, Tamil Nadu, India
India

Krishnaveni Kandasamy
Department of Pharmacy Practice, J.K.K Nattraja College of Pharmacy, Kumarapalayam - 638 183, Namakkal, Tamil Nadu, India
India

Shanmuga Sundaram Rajagopal
Department of Pharmacology, J.K.K Nattraja College of Pharmacy, Kumarapalayam - 638 183, Namakkal, Tamil Nadu, India.
India


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