SILVER NANOPARTICLES FROM MEDICINALLY IMPORTANT EUPHORBIA CYATHOPHORA EXTRACT: BIOSYNTHESIS, CHARACTERIZATION, AND ANTICANCER ACTIVITY.


Robert Lotha, Aravind Sivasubramanian, Meenakshi Sundaram Muthuraman

Abstract


Objective: The present study was aimed at the biosynthesis of silver nanoparticles (AgNPs) using aqueous extract of Euphorbia cyathophora leaves

and testing their anticancer potential using HT-29 cell line model.

Methods: Green synthesis of silver nanoparticles was obtained with the aqueous extract of E. cyathophora. The synthesized nanoparticles were

confirmed initially by ultraviolet-visible spectroscopy. Further, scanning electron microscopy, transmission electron microscopy, and X-Ray diffraction

studies also ensured the presence of silver nanoparticles. Zeta potential studies revealed the stability of the silver nanoparticles.

Results: Antioxidant and anticancer studies of the nanoparticles against HT-29 cell line exhibited remarkable results.

Conclusion: This ensures that the synthesized nanoparticles play an important role in medicinal biology.


Keywords


Green synthesis, Nanoparticles, Euphorbia cyathophora, Scanning electron microscopy, Antioxidant, Anticancer.

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About this article

Title

SILVER NANOPARTICLES FROM MEDICINALLY IMPORTANT EUPHORBIA CYATHOPHORA EXTRACT: BIOSYNTHESIS, CHARACTERIZATION, AND ANTICANCER ACTIVITY.

Keywords

Green synthesis, Nanoparticles, Euphorbia cyathophora, Scanning electron microscopy, Antioxidant, Anticancer.

DOI

10.22159/ajpcr.2018.v11i2.22216

Date

01-02-2018

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 11 Issue 2 February 2018 Page: 154-156

Print ISSN

0974-2441

Online ISSN

2455-3891

Authors & Affiliations

Robert Lotha
Department of Chemistry, School of Chemical and Biotechnology, SASTRA University,Thanjavur, Tamil Nadu, India.
India

Aravind Sivasubramanian
Department of Chemistry, School of Chemical and Biotechnology, SASTRA University,Thanjavur, Tamil Nadu, India.
India

Meenakshi Sundaram Muthuraman
Department of Biotechnology, School of Chemical and Biotechnology, SASTRA University, Thanjavur, Tamil Nadu, India.
India


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