SILVER NANOPARTICLES FROM MEDICINALLY IMPORTANT EUPHORBIA CYATHOPHORA EXTRACT: BIOSYNTHESIS, CHARACTERIZATION, AND ANTICANCER ACTIVITY.

  • Robert Lotha Department of Chemistry, School of Chemical and Biotechnology, SASTRA University,Thanjavur, Tamil Nadu, India.
  • Aravind Sivasubramanian Department of Chemistry, School of Chemical and Biotechnology, SASTRA University,Thanjavur, Tamil Nadu, India.
  • Meenakshi Sundaram Muthuraman Department of Biotechnology, School of Chemical and Biotechnology, SASTRA University, Thanjavur, Tamil Nadu, India.

Abstract

Objective: The present study was aimed at the biosynthesis of silver nanoparticles (AgNPs) using aqueous extract of Euphorbia cyathophora leaves

and testing their anticancer potential using HT-29 cell line model.

Methods: Green synthesis of silver nanoparticles was obtained with the aqueous extract of E. cyathophora. The synthesized nanoparticles were

confirmed initially by ultraviolet-visible spectroscopy. Further, scanning electron microscopy, transmission electron microscopy, and X-Ray diffraction

studies also ensured the presence of silver nanoparticles. Zeta potential studies revealed the stability of the silver nanoparticles.

Results: Antioxidant and anticancer studies of the nanoparticles against HT-29 cell line exhibited remarkable results.

Conclusion: This ensures that the synthesized nanoparticles play an important role in medicinal biology.

Keywords: Green synthesis, Nanoparticles, Euphorbia cyathophora, Scanning electron microscopy, Antioxidant, Anticancer.

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How to Cite
Lotha, R., A. Sivasubramanian, and M. Muthuraman. “SILVER NANOPARTICLES FROM MEDICINALLY IMPORTANT EUPHORBIA CYATHOPHORA EXTRACT: BIOSYNTHESIS, CHARACTERIZATION, AND ANTICANCER ACTIVITY.”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 11, no. 2, Feb. 2018, pp. 154-6, doi:10.22159/ajpcr.2018.v11i2.22216.
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