ASSESSMENT OF QUALITY OF LIFE IN CHRONIC KIDNEY DISEASE PATIENTS USING THE KIDNEY DISEASE QUALITY OF LIFE-SHORT FORMTM QUESTIONNAIRE IN INDIAN POPULATION: A COMMUNITY BASED STUDY
Objective: The objective of this study is to measure the quality of life (QOL) among the chronic kidney disease patients undergoing hemodialysis and
Methods: The present study is observational and prospective, multicentered in an ambulatory setup located in Chennai, South India during November
and December 2013. A total 50 patients were observed by using kidney disease QOL short formTM (KDQOL-SFTM) questionnaire.
Results: A total of 50 end-stage renal disease (ESRD) subjects were enrolled in the present study, 56% and 44% subjects were on hemodialysis and
peritoneal dialysis, respectively. In the present study, 58% were of male subjects and 76% of them were married. About 78% of subjects had diabetes
mellitus as single comorbid. The present study assessed all the four domains of KDQOL in the study subjects. Physical health (PH) was significantly
affected among all the four domains of the KDQOL and an average score was found to be 25.45Â±11.85 (p<0.0015). The average value of 71.93Â±12.35%
(p<0.029) subjects were having satisfaction with dialysis care, which is lower than the recommended value of <65%.
Conclusion: The present study revealed that ESRD patients have a poor QOL and most the affected domain is PH, hence measuring and monitoring
these aspects of QOL could lead to a more patient-centered care and improve the health and well-being among patients with chronic renal failure.
Keywords: Chronic kidney disease, Health related quality of life, Kidney disease quality of life-short formTM, Hemodialysis, Urea reduction ratio
2. Raines N, GonzÃ¡lez M, Wyatt C, Kurzrok M, Pool C, Lemma T, et al. Risk factors for reduced glomerular filtration rate in a Nicaraguan community affected by Mesoamerican nephropathy. MEDICC Rev 2014;16(2):16-22.
3. Agarwal SK, Srivastava RK. Chronic kidney disease in India: Challenges and solutions. Nephron Clin Pract 2009;111(3):c197-203.
4. Schieppati A, Remuzzi G. Chronic renal diseases as a public health problem: Epidemiology, social, and economic implications. Kidney Int Suppl 2005:S7-S10.
5. Acharya VN. Diabetic and hypertensive nephropathy in India. J Assoc Physicians India 2011;59:143.
6. Whelton A, Hamilton CW. Nonsteroidal anti-inflammatory drugs: Effects on kidney function. J Clin Pharmacol 1991;31(7):588-98.
7. Knihs NS, Sartori DL, Zink V, Roza BD, Schirmer J. The experience of patients who need renal transplantation while waiting for a compatible organ. Text Context Nurs FlorianÃ³polis 2013;22(4):1160-8.
8. US Renal Data Systems. The USRDS Dialysis Morbidity and Mortality Study (Wave 1). Annual Data Report. Bethesda, MD: National Institutes of Health, National Institute Diabetes and Digestive and Kidney Diseases; 1996. p. 45-67.
9. Shrestha S, Ghotekar LR, Sharma SK, Shangwa PM, Karki P. Assessment of quality of life in patients of end stage renal disease on different modalities of treatment. JNMA J Nepal Med Assoc 2008;47(169):1-6.
10. Hays RD, Kallich JD, Mapes DL, Coons SJ, Carter WB. Development of the kidney disease quality of life (KDQOL) instrument. Qual Life Res 1994;3(5):329-38.
11. Lowrie EG, Lew NL. The urea reduction ratio (URR): A simple method for evaluating hemodialysis treatment. Contemp Dial Nephrol 1991;12(2):11-20.12. Khan IA, Nasiruddin M, Haque SF, Khan RA. A randomized clinical trial to evaluate the efficacy and safety of Î±-keto amino acids in stage 3 and 4 of chronic kidney disease. Asian J Pharm Clin Res 2014;7(3):21â€‘4.
13. Rani VN, Soundararajan P, Samyuktha CH, Kannan G, Thennarasu P. Impact of clinical pharmacist provided education on medication knowledge and adherence of hemodialysis patients in a south Indian university hospital. Asian J Pharm Clin Res 2013;6(4):24-7.
14. Chow FY, Briganti EM, Kerr PG, Chadban SJ, Zimmet PZ, Atkins RC. Health-related quality of life in Australian adults with renal insufficiency: A population-based study. Am J Kidney Dis 2003;41(3):596-604.
15. Apostolou T, Hutchison AJ, Boulton AJ, Chak W, Vileikyte L, Uttley L, et al. Quality of life in CAPD, transplant, and chronic renal failure patients with diabetes. Ren Fail 2007;29(2):189-97.
16. Paniagua R, Amato D, Vonesh E, Guo A, Mujais S. Mexican Nephrology Collaborative Study Group. Health-related quality of life predicts outcomes but is not affected by peritoneal clearance: The ADEMEX trial. Kidney Int 2005;67:1093-104.
17. McFarlane PA, Tobe SW, Culleton B. Improving outcomes in diabetes and chronic kidney disease: The basis for Canadian guidelines. Can J Cardiol 2007;23(7):585-90.
18. National Kidney Foundation. K/DOQI Clinical Practice Guidelines for Chronic Kidney Disease. Evaluation, Classification and Stratification. National Kidney Foundation, Inc.; 2002. Available from: http://www.kidney.org/professionals/kdoqi/guidelines_ckd/toc.htm.18. [Last accessed on 2014 Jan].
The publication is licensed under CC By and is open access. Copyright is with author and allowed to retain publishing rights without restrictions.