EVALUATION OF IN VITRO ANTHELMINTIC PROPERTIES OF AVICENNIA MARINA LEAVES


Gana Manjusha Kondepudi

Abstract


 Objectives: The purpose of the present study was to determine the anthelmintic properties of chloroform, methanol and aqueous extracts of Avicennia marina leaves on Indian earthworm- Pheretima posthuma.

Methods: Three concentrations of each extract (25 mg/ml, 50 mg/ml, and 75 mg/ml) were studied in this activity to determine the time of paralysis (vermifuge) and the time of the death of the worms (vermicidal). Piperazine citrate in the same concentrations was taken a reference standard and normal water was taken as control. The time taken for paralysis and death of the worms was recorded.

Results: All the extracts showed dose-dependent and a significant activity was shown at higher concentration (75 mg/ml). Methanolic extract showed peak activity at a concentration of 75 mg/ml.

Conclusion: Based on the results it was found that the leaves of A. marina possess vermifuge and vermicidal activities and can be used as an effective anthelmintic.


Keywords


Anthelmintic, Mangroves, Pheretima posthuma, Vermifuge, Vermicide.

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About this article

Title

EVALUATION OF IN VITRO ANTHELMINTIC PROPERTIES OF AVICENNIA MARINA LEAVES

Topics

pharmaceutical sciences

Keywords

Anthelmintic, Mangroves, Pheretima posthuma, Vermifuge, Vermicide.

DOI

10.22159/ajpcr.2018.v11i4.23605

Date

01-04-2018

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 11 Issue 4 April 2018 Page: 303-305

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

20 Views | 64 Downloads

Authors & Affiliations

Gana Manjusha Kondepudi
Department of Pharmacognosy and Phytochemistry, Vignan Institute of Pharmaceutical Technology, Besides Vsez, Kapujaggraju Peta Duvvada, Visakhapatnam, Andhra Pradesh, India.
India


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