A PRESCRIPTION PATTERN STUDY OF RESPIRATORY TRACT INFECTIONS IN PAEDIATRIC INDOOR PATIENTS IN A TERTIARY CARE TEACHING HOSPITAL - A PROSPECTIVE OBSERVATIONAL STUDY

Authors

  • Vandana Badar Department of Pharmacology, Indira Gandhi Government Medical College, Nagpur, Maharashtra, India.
  • Vidisha Parulekar Department of Pharmacology, Indira Gandhi Government Medical College, Nagpur, Maharashtra, India.
  • Priti Garate Department of Pharmacology, Indira Gandhi Government Medical College, Nagpur, Maharashtra, India.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11i7.24407

Keywords:

Antibiotics, Infants, Nil, Anatomical Therapeutic Chemical classification

Abstract

Objectives: The objectives of the study were as follows: (1) To study the prescription patterns in Respiratory tract infections (RTI) in indoor patients in pediatric wards. (2) To check the rationality of treatment according to Modified Kunin's rationality criteria. (3)To analyze the data of RTI by Anatomical Therapeutic Chemical classification.

Methods: It was a non-interventional, prospective, observational study which was conducted in indoor pediatric patients in a tertiary care teaching hospital in India. Data were analyzed and evaluated according to the WHO rational use of drugs guidelines.

Study sample: The study sample was 174.

Study duration: The study duration was August 15, 2016–September 15, 2016.

Results: Males (63.79%) were more as compared to females (36.20%), and the highest number of cases was seen in infants (62.06%). Acute bronchiolitis (54.02%) was highest in the incidence followed by Wheeze Associated Lower Respiratory Tract Infection (WALRI) (30.45%). The average duration of patient stay in hospital was 4.71 days whereas 93.33% were polytherapy and mostly prescribed antibiotic was amoxicillin-clavulanic acid in acute bronchiolitis and WALRI. Salbutamol (40.84%) and Ipratropium Bromide (39.43%) were the commonly prescribed respiratory medicines. Oral route (42.27%) was the most common route of administration. 56.11% drugs were prescribed by generic name.

Conclusion: Standard treatment guidelines for the treatment of RTI need to be urgently developed and strictly implemented.

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Author Biographies

Vandana Badar, Department of Pharmacology, Indira Gandhi Government Medical College, Nagpur, Maharashtra, India.

ASSOCIATE PROFESSOR, DEPARTMENT OF PHARMACOLOGY

Vidisha Parulekar, Department of Pharmacology, Indira Gandhi Government Medical College, Nagpur, Maharashtra, India.

RESIDENT, DEPARTMENT OF PHARMACOLOGY

Priti Garate, Department of Pharmacology, Indira Gandhi Government Medical College, Nagpur, Maharashtra, India.

RESIDENT, DEPARTMENT OF PHARMACOLOGY

References

Sanz EJ, Bergman U, Dahlstorm M. Paediatric drug prescribing. A comparison of Tenerife (Canary Islands, Spain) and Sweden. Eur J Clin Pharmacol 1989;37:65-8.

Summers RS, Summers B. Drug prescribing in paediatrics at a teaching hospital serving a developing community. Ann Trop Paediatr 1986;6:129-33.

Vashishtha VM. Current status of tuberculosis and acute respiratory infections in India: Much more needs to be done. Indian J Pediatr 2010;47:88-9.

Mohan S, Dharamraj K, Dindial R, Mathur D, Parmasad V, Ramdhanie J, et al. Physician behaviour for antimicrobial prescribing for pediatric URTI: A survey in general practice in Trinidad, West Indies. Ann Clin Microbiol Antimicrob 2004;3:11.

Wattal C, Goel N, Oberoi JK, Raveendran R, Datta S, Prasad KJ. Surveillance of multidrug resistant organisms in tertiary care hospital in Delhi, India. J Assoc Physicians India 2010;58 Suppl:32 6.

Sachdeva PD, Patel BG. Drug utilization studies scope and future perspectives. Int J Pharm Biol Res 2010;1:11 6.

WHO. The Anatomical Therapeutic Chemical Classification System with Defined Daily Doses (ATC/DDD). Norway: WHO; 2004. Available from: http://www.who.int/classifications/actddd/en. [Last accessed on 2010 Oct 22].

Iyer GS, Patel PP, Panchal JR, Dikshit RK. An analysis of the pharmacological management of respiratory tract infections in pediatric in-patients at a tertiary care teaching hospital. Int J Med Public Health 2013;3:140-5.

Gajbhiye VP, Kale RS, Vilhekar KY, Bahekar SE. Drug utilization study on antimicrobials use in lower respiratory tract infection in Pediatric Intensive Care Unit of Rural Tertiary Care Hospital. J Med Soc 2016;30:146-8.

Safaeian L, Mahdanian A, Hashemi-Fesharaki M, Salami S, Kebriaee- Zadeh J, Sadeghian G. General physicians and prescribing pattern in Isfahan, Iran. Oman Med J 2011;26:205-6.

Jose S, Rajashekarachar Y, Basavanthappa SP, Naidu BR. Evaluation of antibiotic usage on lower respiratory tract infections in paediatric department- an observational study. Int J Contemp Pediatr 2016;3:146-49. Available from: www.ejmanager.com/mnstemps/119/119-1445084158. pdf. [Last cited on 2016 Oct 28].

Pasha SZ, Prasad BD, Shalem L, Chand TB, Veeramani G. Prescribing pattern and use of antibiotics and combination of antibiotics in a tertiary care teaching hospital. Indo Am J Pharm Res 2014;4:3172-81.

Shruthi KV, Bhandare B, Adarsh E. Prescribing pattern of drugs in paediatric in-patients with lower respiratory tract infection at a Tertiary care hospital. World J Pharm Pharm Sci 2016;5:2396-409.

WHO. How to Investigate Drug use in Health Facilities: Selected Drug use Indicators. WHO/DAP/93. Geneva: World Health Organization; 2010.

Triruthopu NS, Mateti UV, Bariri R, Sivva D, Martha S. Drug utilization pattern in south Indian paediatric population: A prospective study. Perspect Clin Res 2014;51:78-83.

Deshmukh S, Mahajan M. A study of prescription pattern of antibiotics in paediatric in-patients at a tertiary care hospital in central. India Int J Pharmacol Res 2016;6:286-90.

Mohapatra S, Tripathy S, Balaji C, Rani RJ, Sekar P. Prescribing pattern of antimicrobial agents in pediatrics department of a teaching hospital. Int J Basic Clin Pharmacol 2015;4:753-6. Available from: http://dx.doi. org/10.18203/2319-2003.ijbcp20150385. [Last cited on 2016 Oct 28].

Arute JE, Adigom DO, Erach PO, Eichie EF, Eniojukan JF. Antibiotic prescription pattern in the paediatric ward of a tertiary health care facility in southern Nigeria. J Pharm Allied Sci 2011;8:34-42.

Pramil T, Ahlawat R, Gupta G. Prescription practice in patients of upper respiratory tract infection at a pediatric outpatient clinic in Punjab. Indian J Pharm Pract 2014;7:26-32.

Kumar RS, Ray IM, Mohanty NC, Mukhia RK, Deshmukh YA. Assessment of usage of antibiotic and their pattern of antibiotic sensitivity test among childhood fever. Int J Pharm Pharm Sci 2014;6:296-9.

Kumar MA, Ramand KT, Ramasamy C. Cross sectional prospective study on drug utilization in an outpatient paediatric department of tertiary care teaching hospital. Glob J Pharmacol 2013;7:99-102.

Choudhury DK, Bezbaruah BK. Antibiotic prescriptions pattern in paediatric in-patient department. J Appl Pharm Sci 2013;3:144-8.

Satoskar RS, Rege N. Routes of administration and dosage. Pharmacology and Pharmacotherapeutics. 24th ed. India: Elsevier; 2015. p. 7.

Vlahovic-Palcevski V, Francetic I, Palcevski G, Novak S, Abram M, Bergman U. Antimicrobial use at a university hospital: Appropriate or misused? A qualitative study. Int J Clin Pharmacol Ther 2007;45:169-74.

Spurling GK, Doust J, Del Mar CB, Eriksson L. Antibiotics for bronchiolitis in children. Cochrane Database Syst Rev 2011;15:CD005189.

Published

07-07-2018

How to Cite

Badar, V., V. Parulekar, and P. Garate. “A PRESCRIPTION PATTERN STUDY OF RESPIRATORY TRACT INFECTIONS IN PAEDIATRIC INDOOR PATIENTS IN A TERTIARY CARE TEACHING HOSPITAL - A PROSPECTIVE OBSERVATIONAL STUDY”. Asian Journal of Pharmaceutical and Clinical Research, vol. 11, no. 7, July 2018, pp. 251-4, doi:10.22159/ajpcr.2018.v11i7.24407.

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