MICROBIAL ETIOLOGY AND ANTIBACTERIAL RESISTANCE PATTERNS OF DACRYOCYSTORHINOSTOMY CASES IN THE NORTH OF IRAN S

Authors

  • Shadman Nemati Rhino-Sinus, Ear, and Skull Base Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.
  • Ali Mojtahedi Department of Microbiology, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
  • Sina Montazeri Rhino-Sinus, Ear, and Skull Base Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.
  • Pegah Alizadeh Pahlavan Rhino-Sinus, Ear, and Skull Base Diseases Research Center, Guilan University of Medical Sciences, Rasht, Iran.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11i7.25477

Keywords:

Antibiotic resistance, Bodkin tube, Dacryocystorhinostomy

Abstract

Objective: Nasolacrimal duct obstruction is an annoying medical condition in both ophthalmology and otolaryngology practices. As prophylactic antibiotic therapy decreases the rates of infections, understanding the prompt microbial spectrum of the pathogens has been revealed to be highly effective in such patients. We evaluated the microbial growth and bacterial resistance patterns of Bodkin tube samples obtained from patients who underwent dacryocystorhinostomy (DCR).

Methods: A total number of 72 patients were enrolled in the study, and their Bodkin tube samples were cultured 8–12 weeks after DCR at Amir-Al Momenin University Hospital of Rasht, in the north of Iran.

Results: Staphylococcus epidermidis and Aspergillus fumigatus were the most common bacterial and fungal species derived from the cultures, and 23.6% and 36.1% of the patients had neither bacterial nor fungal growth, respectively. The highest antibiotic resistance rates were toward cefazolin and cloxacillin among all the studied antibiotics.

Conclusion: Majority of cases had positive bacterial or fungal growth in their samples. Considering microbial resistance, proper antibiotic selection is recommended for the patients undergoing DCR.

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References

Subramanian A, Yessaian S. Screening and antibiogram pattern of bacterial ophthalmic infections. Int J Pharm Pharm Sci 2015;7:412-5.

Murugan N, Malathi J, Therese KL, Madhavan HN. Antimicrobial susceptibility and prevalence of extended spectrum betalactamase (ESBL) and metallo betalactamase (MBL) and its co-existence among Pseudomonas aeruginosa recovered from ocular infections. Int J Pharm Pharm Sci 2015;7:147-51.

Ali MJ, Manderwad G, Naik MN. The microbiological spectrum and antibiotic sensitivity profile of extubated silicone stents following dacryocystorhinostomy. Orbit 2013;32:298-303.

Kim SE, Lee SJ, Lee SY, Yoon JS. Clinical significance of microbial growth on the surfaces of silicone tubes removed from dacryocystorhinostomy patients. Am J Ophthalmol 2012;153:253-7.e1.

Savino G, Battendieri R, Traina S, Corbo G, D’Amico G, Gari M, et al. External vs. endonasal dacryocystorhinostomy: Has the current view changed? Acta Otorhinolaryngol Ital 2014;34:29-35.

Kamal S, Bodh SA, Goel R, Kumar S. Clinical significance of microbial growth on the surfaces of silicone tubes removed from dacryocystorhinostomy patients. Am J Ophthalmol 2012;153:189-90.

Carifi M, Carifi G. Clinical significance of microbial growth on the surfaces of silicone tubes removed from dacryocystorhinostomy patients. Am J Ophthalmol 2012;154:418-9.

Mikaniki E, Rasolinejad S. Efficacy of dacryocystorhinostomy with catheter insertion or bodkin tube in the treatment of nasolacrimal obstruction. J Babol Uni Med Sci 2007;9:37-40.

Sun X, Liang Q, Luo S, Wang Z, Li R, Jin X. Microbiological analysis of chronic dacryocystitis. Ophthalmic Physiol Optics 2005;25:261-3.

Nemati S, Nasiri M, Medghalchi A, Rouhi R. Comparison of endonasal endoscopic versus external dacryocystorhinostomy results for adult patients with acquired nasolacrimal duct obstruction. J Guilan Uni Med Sci 2014;23:66-74.

Ojaghi H, Masoumi R, Mohammadi M. Dacryocystorhinostomy with budkin tube operation in patients with chronic dacryocystitis. J Ardabil Uni Med Sci 2008;8:7-13.

Chong KK, Lai FH, Ho M, Luk A, Wong BW, Young A. Randomized trial on silicone intubation in endoscopic mechanical dacryocystorhinostomy (SEND) for primary nasolacrimal duct obstruction. Ophthalmology 2013;120:2139-45.

Walland MJ, Rose GE. Factors affecting the success rate of open lacrimal surgery. Br J Ophthalmol 1994;78:888-91.

Walland MJ, Rose GE. Soft tissue infections after open lacrimal surgery. Ophthalmology 1994;101:608-11.

Parsa K, Schaudinn C, Gorur A, Sedghizadeh PP, Johnson T, Tse DT, et al. Demonstration of bacterial biofilms in culture-negative silicone stent and jones tube. Ophthal Plast Reconstr Surg 2010;26:426-30.

Walland MJ, Rose GE. The effect of silicone intubation on failure and infection rates after dacryocystorhinostomy. Ophthalmic Surg 1994;25:597-600.

Zaman M, Babar TF, Abdullah A. Prospective randomized comparison of dacryocystorhinostomy (DCR) with and without intubation. Pak J Med Res 2005;44:75-8.

Feng YF, Cai JQ, Zhang JY, Han XH. A meta-analysis of primary dacryocystorhinostomy with and without silicone intubation. Can J Ophthalmol 2011;46:521-7.

Choung HK, Khwarg SI. Selective non-intubation of a silicone tube in external dacryocystorhinostomy. Acta Ophthalmol Scand 2007;85:329-32.

Pandya VB, Lee S, Benger R, Danks JJ, Kourt G, Martin PA, et al. External dacryocystorhinostomy: Assessing factors that influence outcome. Orbit 2010;29:291-7.

Vicinanzo MG, McGwin G, Boyle M, Long JA. The consequence of premature silicone stent loss after external dacryocystorhinostomy. Ophthalmology 2008;115:1241-4.

Wayne P. Performance Standards for Antimicrobial Susceptibility Testing. Clinical and Laboratory Standards Institute (CLSI). 25th Informational Supplement; 2015;M100-S25.

Haghighatpanah M, Nejad AS, Mojtahedi A, Amirmozafari N, Zeighami H. Detection of extended-spectrum beta-lactamase (ESBL) and plasmid-borne blaCTX-M and blaTEM genes among clinical strains of Escherichia coli isolated from patients in the north of Iran. J Glob Antimicrob Resist 2016;7:110-3.

Tavakoly T, Jamali S, Mojtahedi A, Mirzaei MK, Shenagari M. The prevalence of CMY-2, OXA-48 and KPC-2 genes in clinical isolates of Klebsiella spp. Cell Mol Biol (Noisy-le-grand) 2018;64:40-4.

Khashei R, Sarie HS, Alfatemi MH, Zomorodian K. Antimicrobial resistance patterns of colonizing microflora on the personnel hands and noses working in the neonatal intensive care unit (NICU). World Appl Sci J 2014;30:1232-7.

Hartikainen J, Lehtonen OP, Saari KM. Bacteriology of lacrimal duct obstruction in adults. Br J Ophthalmol 1997;81:37-40.

Zalipour M, Ebrahim-Saraie HS, Sarvari J, Khashei R. Detection of biofilm production capability and icaA/D genes among staphylococci isolates from Shiraz, Iran. Jundishapur J Microbiol 2016;9:e41431.

Published

07-07-2018

How to Cite

Nemati, S., A. Mojtahedi, S. Montazeri, and P. Alizadeh Pahlavan. “MICROBIAL ETIOLOGY AND ANTIBACTERIAL RESISTANCE PATTERNS OF DACRYOCYSTORHINOSTOMY CASES IN THE NORTH OF IRAN S”. Asian Journal of Pharmaceutical and Clinical Research, vol. 11, no. 7, July 2018, pp. 407-11, doi:10.22159/ajpcr.2018.v11i7.25477.

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Original Article(s)