IN VITRO ANTIBACTERIAL ACTIVITY AND GAS CHROMATOGRAPHY-MASS SPECTROMETRY ANALYSIS OF ETHANOLIC EXTRACT OF LEAVES OF ELETTARIA CARDAMOMUM L. MATON

  • Prabu P Department of Chemistry, VELTECH, Avadi, Chennai - 600 062, Tamil Nadu, India.
  • Edayadulla N Department of Chemistry, VELTECH, Avadi, Chennai - 600 062, Tamil Nadu, India.
  • Anand S Department of Chemistry, Saveetha Engineering College, Thandalam, Chennai-602 105, Tamil Nadu, India.

Abstract

Objective: The objective of the present study is to determine the possible phytoconstituents identified by gas chromatography and mass spectrometry (GC-MS) analysis of an ethanolic leaves extract of Elettaria cardamomum L. Maton.

Methods: The extraction of E. cardamomum was done by cold solvent extraction system at room temperature. GC-MS analysis of lyophilized ethanolic leaves extract of plant samples was carried out by GC-MS-GC Clarus 500 Perkin Elmer.

Results: In E. cardamomum, 21 phytochemicals were identified among which retinal, 9-cis-showed the highest area (44.86%) and benzeneethanamine, α-methyl- showed the lowest area (0.12%). The major compounds identified were retinal, 9-cis-, 1-heptatriacotanol, phytol, n-hexadecanoic acid, naphthalene,decahydro-1,1,4atrimethyl-6-methylene-5-(3-methyl-2-4-pentadienyl)-[4aS-(4aα,5α,8aα)]-, β-pinene, 2H-pytan-3-ol,6- ethenyltetrahydro-2,2,6-trimethyl-and cyclopropane, trimethanol, (2-methyl-1-propanylidene).

Conclusion: GC-MS analysis revealed the presence of hydrocarbon alkane, ester, terpenes, phenolic compounds, steroids, and fatty acids in E. cardamomum. These active phytoconstituents contribute to the medicinal efficacy of the plant, and the plant can be used for the sourcing of these compounds.

Keywords: Elettaria cardamomum, Gas chromatography-mass spectrometry, Phytoconstituents, Antibacterial.

Author Biography

Prabu P, Department of Chemistry, VELTECH, Avadi, Chennai - 600 062, Tamil Nadu, India.

Associate Professor

Department of Chemistry

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P, P., E. N, and A. S. “IN VITRO ANTIBACTERIAL ACTIVITY AND GAS CHROMATOGRAPHY-MASS SPECTROMETRY ANALYSIS OF ETHANOLIC EXTRACT OF LEAVES OF ELETTARIA CARDAMOMUM L. MATON”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 12, no. 1, Jan. 2019, pp. 73-75, doi:10.22159/ajpcr.2019.v12i1.27393.
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