• AVANI BHOSALE Department of Cardio Respiratory Sciences, Faculty of Physiotherapy, Krishna University, Karad, Maharashtra, India.
  • POOVISHNU DEVI THANGAVELU Department of Cardiorespiratory Sciences, Faculty of Physiotherapy, Krishna University, Karad, Maharashtra, India.


Objectives: The objectives of this study were as follows: (1) To find the effect of conventional physiotherapy along with medications on Type II diabetes mellitus (DM) individuals and (2) to find the effect of lifestyle modification (LSM) and conventional physiotherapy with medications on Type II DM individuals.

Methods: Ethical clearance was obtained from the institutional ethical committee. A total of 70 Type II DM individuals were assessed and 64 were included in this study based on inclusion criteria, the individuals were allocated into two groups: Group A (n=32) received conventional physiotherapy along with prescribed diabetic medications and Group B (n=32) received LSM and conventional physiotherapy with prescribed diabetic medications. Pre- and post-test were done for plasma glucose, serum insulin, glycated hemoglobin (HbA1c), total cholesterol, triglycerides, high-density lipoprotein-C, low-density lipoprotein by blood test, exercise tolerance by 6-min walk test, and quality of life (QOL) by SF-36 questionnaire, and the outcome measures were analyzed after 3 months.

Results: Intergroup statistical analysis for HbA1c (p<0.0001) and QOL (p<0.0001) revealed extremely significant difference post-intervention. Analysis of HbA1c test for Group A (p=0.0652) was not significant and for Group B (p<0.0001) was extremely significant. Moreover, QOL was significant for Group A (p=0.0004) as well as for Group B (p<0.0001).

Conclusion: The study results concluded that LSM was significantly effective in reducing HbA1c levels, exercise tolerance, plasma glucose, serum glycerine, and total cholesterol and improving QOL compared to conventional exercise.

Keywords: Lifestyle modification, Type II diabetes mellitus, Resistance exercises, Walking.


1. Ramachandran A, Snehalatha C. Diabetes mellitus; epidemiology and basic considerations of diabetes. In: API Textbook of Medicine. 10th ed., Vol. 1. New Delhi: Jaypee Brother’s Medical Publishers; 2015. p. 467-4.
2. Sanghani NB, Parchwani DN, Palandurkar KM, Shah AM, Dhanani JV. Impact of lifestyle modification on glycemic control in patients with type 2 diabetes mellitus. Indian J Endocrinol Metab 2013;17:1030-9.
3. Harris MI, Hadden WC, Knowler WC, Bennett PH. Prevalence of diabetes and impaired glucose tolerance and plasma glucose levels in U.S. population aged 20-74 yr. Diabetes 1987;36:523-34
4. Patil RS, Gothankar SJ. Prevalence of type-2 diabetes mellitus and associated risk factors in an urban slum of Pune city, India. Natl J Med Res 2013;3:346-9.
5. Tripathi KD. Insulin, oral hypoglycaemic drugs and glucagon. In: Essentials of Medical Pharmacology. 6th ed. New Delhi: Jaypee Brothers Medical Publishers; 2010. p. 258-81.
6. Kalpana M, Ruckmani A, Janti SS, Eerike M, Prabhu RL. Burden of therapy in patients suffering from diabetes mellitus and hypertension. Int J Pharm Pharm Sci 2015;9:210-5.
7. Foreyt JP, Poston WS. The challenge of diet, exercise and lifestyle modification in the management of the obese diabetic patient. Int J Obes Relat Metab Disord 1999;23 Suppl 7:S5-11.
8. Thent ZC, Das S, Henry LJ. Role of exercise in the management of diabetes mellitus: The global scenario. PLoS One 2013;8:e80436.
9. Patil VR, Thangvelu PD. Effectiveness of lifestyle modification on weight loss and quality of life in obese women with polycystic ovarian syndrome. Asian J Pharm Clin Res 2018;11:333-6.
10. Sherwani SI, Khan HA, Ekhzaimy A, Masood A, Sakharkar MK. Significance of hbA1c test in diagnosis and prognosis of diabetic patients. Biomark Insights 2016;11:95-104.
11. Tan S, Li W, Wang J. Effects of six months of combined aerobic and resistance training for elderly patients with a long history of type 2 diabetes. J Sports Sci Med 2012;11:495-501.
130 Views | 124 Downloads
How to Cite
BHOSALE, A., and P. D. THANGAVELU. “EFFECT OF LIFESTYLE MODIFICATION IN TYPE II DIABETES MELLITUS INDIVIDUALS”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 12, no. 2, Jan. 2019, pp. 381-3, doi:10.22159/ajpcr.2019.v12i2.29668.
Original Article(s)