EFFECT OF FEEDING WITH HERB OF ERYTHRINA VARIEGATA TO BIOCOMPATIBILITY OF THE COCOON FIBER OF WILD SILK MOTH ATTACUS ATLAS FOR FUTURE APPLICATION AS BIOCOMPATIBLE OF SILK SUTURES


Tjokorda Sari Nindhia, Tjokorda Gde Tirta Nindhia, I Wayan Surata, Zdenek Knejzlik, Tomas Ruml

Abstract


Objectives: Silk is biocompatible as biomaterial and has been used commercially as sutures. More interesting properties of the silk are that the mechanical properties exceed all natural polymer and synthetic materials. In this research, a type of silk suture is being developed from species of Attacus atlas to obtain better biocompatible sutures. A. atlas is a species of silk moth that consume not only single types of leaves. The Quality of cocoon fiber then can be arranged base on the types of the leaves that is consumed. Better biocompatibility sutures comparing with recent commercial silk sutures which is not biocompatible, can be achieved by feeding with variety types of leaves. Silk suture that already established in the market is a base product of Bombyx mori species of silk which is only consume one type of leaf (mulberry leaves).

Methods: In this research, the A. atlas cocoon was produced by feeding with herb Erythrina variegate. The microstructure was observed, element composition as well as biocompatibles properties was investigated.

Results: A high composition of kalium (K) as well as chloride (Cl) is identified in the fiber. The released fiber from cocoon also indicates high biocompatibility that is promising as biocompatible suture.

Conclusion: The biocompatible fiber for future application as sutures is possible to be prepared by feeding the wild silkworm of A. atlas with leaf of E. variegate. The fiber is found rich with kalium (K) as well as chloride (Cl) with irregular shape of crystal at the surface of the fiber.


Keywords


Silk, herb, Erythrina variegate, Sutures, Biocompatibility.

| PDF |

References


Chen F, Porter DF, Vollrath F. Morphology and structure of silkworm cocoons. Mater Sci Eng C 2012;32:772-8.

Altman GH, Diaz F, Jakuba C, Calabro T, Horan RL, Chen J, et al. Silk-based biomaterials. Biomaterials 2003;24:401-16.

Chen MM, Li Y, Chen M, Wang H, Li Q, Xia RX, et al. Complete mitochondrial genome of the atlas moth, Attacus atlas (Lepidoptera: Saturniidae) and the phylogenetic relationship of Saturniidae species. Gene 2014;545:95-101.

Nindhia TG, Koyoshi Y, Kaneko A, Sawada H, Ohta M, Hirai S, et al. Hydroxyapatite-silk functionally graded material by pulse electric current sintering. Trends Biomater Artif Organs 2008;22:28-33.

Jones CG, Young AM, Jones TH, Blum MS. Chemistry and possible roles of cuticular alcohols comp. Biochem Physiol 1982;73:797-801.

Muthukrishnan S, Palanisamy S, Subramanian S, Selvaraj S, Mari KR, Kuppulingam R. Phytochemical profile of Erythrina variegata by using high-performance liquid chromatography and gas chromatography-mass spectroscopy analyses. J Acupunct Meridian Stud 2016;9:207-12.

Jyothirmayi T, Rao PG, Walde SG. Nitrogen extractability and functional properties of defatted Erythrina variegata flour. Food Chem 2006;96:242-7.

Zhang Y, Li X, Lai WP, Chenc B, Chow HK, Fu C, et al. Anti-osteoporotic effect of Erythrina variegata in ovariectomized rats. J Ethnopharmacol 2007;109:165-9.

Tanaka H, Hirata M, Etoh H, Shimizu H, Sako M, Murata J, et al. Eryvarins F and G, 3-phenoxychromones from the roots of Erythrina variegate. Photochemistry 2003;62:1243-46.

Goun E, Cunningham G, Chu D, Nguyen C, Miles D. Antibacterial and antifungal activity of Indonesian ethnomedical plants. Fitoterapia 2003;76:592-96.




About this article

Title

EFFECT OF FEEDING WITH HERB OF ERYTHRINA VARIEGATA TO BIOCOMPATIBILITY OF THE COCOON FIBER OF WILD SILK MOTH ATTACUS ATLAS FOR FUTURE APPLICATION AS BIOCOMPATIBLE OF SILK SUTURES

Keywords

Silk, herb, Erythrina variegate, Sutures, Biocompatibility.

DOI

10.22159/ajpcr.2018.v11s3.30019

Date

06-10-2018

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 11 Special issue 3 2018 Page: 20-23

Print ISSN

0974-2441

Online ISSN

2455-3891

Authors & Affiliations

Tjokorda Sari Nindhia
Faculty of Veterinary Medicine Udayana University, Denpasar, Bali, Indonesia.
Indonesia

Tjokorda Gde Tirta Nindhia
Department of Mechanical Engineering, Faculty of Engineering, Udayana University, Jimbaran, Bali, Indonesia.
Indonesia

I Wayan Surata
Department of Mechanical Engineering, Faculty of Engineering, Udayana University, Jimbaran, Bali, Indonesia.
Indonesia

Zdenek Knejzlik
Department of Biochemistry and Microbiology, Faculty of Food and Biochemical Technology, Prague, Czech Republic.
Czech Republic

Tomas Ruml
Department of Biochemistry and Microbiology, Faculty of Food and Biochemical Technology, Prague, Czech Republic.
Czech Republic


Article Tools


Email this article (Login required)
Email the author (Login required)

Refbacks

  • There are currently no refbacks.