• CHEENAM B Department of Clinical Nutrition, Fortis Escorts Hospital, Amritsar, Punjab, India.
  • LEENA P Department of Botany, Seth G.L. Bihani S.D (P.G.) College, Sri Ganganagar, Rajasthan, India.
  • VIKAS K Department of Food Technology and Nutrition, Lovely Professional University, Phagwara, Punjab, India.


Objective: The present study was conducted with a goal to analyze and assess the effect of sunflower seeds on the serum cholesterol and low-density lipoprotein (LDL) levels.

Methods: A total of 60 patients comprising 34 males and 26 females were selected for the given study. The patients were divided into case and control groups. Various anthropometric measurements such as weight, height, and blood pressure along with certain biochemical parameters including cholesterol and LDL were recorded for these patients pre- and post-supplementation of 2 g of sunflower seeds for 6 months.

Results: The patients in the experimental group showed a significant and rapid difference (p<0.05) in comparison to the control intervention. The cholesterol levels in the case group reduced from 254.6±21.40 to 183.40±3.01 mg/dl, whereas, in control group, it reduced from 234.53±13.54 to 194.50±6.16 mg/dl. Similarly, the LDL levels in the case group decreased from 155.28±8.48 to 122.70±2.94 mg/dl; in contrast, in control group, it decreased from 159.53±6.04 to 140.53±1.11 mg/dl, respectively.

Conclusion: The study conducted concluded that sunflower seeds can be used as an adjuvant in treating the raised cholesterol and LDL levels in the blood serum which could otherwise lead various cardiac disorders (both major and minor).

Keywords: Sunflower seeds, Cholesterol, Low-density lipoprotein, Cardiac disorders, Supplementation, Nutrition-intervention.

Author Biography

CHEENAM B, Department of Clinical Nutrition, Fortis Escorts Hospital, Amritsar, Punjab, India.

PhD Scholar, Sr. Dietitian


1. Prabhakaran D, Jeemon P, Roy A. Cardiovascular diseases in India: Current epidemiology and future directions. Circulation 2016;133:1605-20.
2. Niharika V. Introduction to hyperlipidaemia and its treatment: A review. Int J Curr Pharm Res 2016;9:6-14.
3. Soutar AK, Naoumova RP. Autosomal recessive hypercholesterolemia. Semin Vasc Med 2004;4:241-8.
4. Austin MA, Hutter CM, Zimmern RL, Humphries SE. Familial hypercholesterolemia and coronary heart disease: A HuGE association review. Am J Epidemiol 2004;160:421-9.
5. Carmena R, Duriez P, Fruchart JC. Atherogenic lipoprotein particles in atherosclerosis. Circulation 2004;109:32-7.
6. Kontush A, Chapman MJ. Antiatherogenic small, dense HDL-guardian angel of the arterial wall? Nat Clin Pract Cardiovasc Med 2006;3: 144-53.
7. Allain CC, Poon LS, Chan CS, Richmond W, Fu PC. Enzymatic determination of total serum cholesterol. Clin Chem 1974;20:470-5.
8. Ansminger AH, Ensminger ME, Kondale JE, Robson JR. Foods and Nutrition Encyclopedia. 2nd ed. California: Pegus Press Publishers; 1983.
9. Krimer MV, Madarev PS, Vastag Z, Preedy V, Patel V, Ronald W. Nuts and Seeds in Health and Disease Prevention. 1st ed. St. Louis, Mo: Elsevier Publications; 2011.
10. Phillips KM, Ruggio DM, Ashraf-Khorassani M. Phytosterol composition of nuts and seeds commonly consumed in the United States. J Agric Food Chem 2005;53:9436-45.
11. Yoshida H, Takagi S, Mitsuhashi S. Tocopherol distribution and oxidative stability of oils prepared from the hypocotyl of soybeans roasted in a microwave oven. J Am Oil Chem Soc 1999;76:915-20.
12. Shafiya SK, Naga SS, Mohan CU, Divya P. Assessment of the nutritional behaviour among college students-a survey. Int J Pharm Pharm Sci 2018;10:1-6.
13. Prasad K. Dietary flax seed in prevention of hypercholesterolemic atherosclerosis. Atherosclerosis 1997;132:69-76.
14. Kassaian N, Azadbakht L, Forghani B, Amini M. Effect of fenugreek seeds on blood glucose and lipid profiles in Type 2 diabetic patients. Int J Vitam Nutr Res 2009;79:34-9.
15. Madar Z, Abel R, Samish S, Arad J. Glucose-lowering effect of fenugreek in non-insulin dependent diabetics. Eur J Clin Nutr1988;42:51-4.
16. Wood C, Rebecca S. The Whole Foods Encyclopaedia. 1st ed. New York: Prentice-Hall Press; 1988.
17. Leenawaty L, Renny I, Ekawati D, Sulistiawatid E, Herawati I, Dumilah R, et al. Hypocholesterolemic effect and pigments composition of herbal medicine containing higher and lower plants. Int J Pharm Pharm Sci 2017;9:97-103.
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How to Cite
B, C., L. P, and V. K. “EFFECTS OF SUNFLOWER SEEDS ON CHOLESTEROL AND LOW-DENSITY LIPOPROTEIN LEVELS IN PATIENTS WITH DYSLIPIDEMIA”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 12, no. 3, Mar. 2019, pp. 556-9, doi:10.22159/ajpcr.2019.v12i3.31032.
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