QUALITY CONTROL EVALUATION OF IN HOUSE PREPARED POLYHERBAL AYURVEDIC FORMULATION SAPTAVIMSATIKA GUGGLU

  • Pankaj Nainwal Assistant Professor School of Pharmacy, Graphic Era Hill University Dehradun, Uttarakhand

Abstract

Introduction: Plants and their constituent are having potential of treating any human suffering in form of disease. Various combination of plant extract is used as a remedy for treating these disorders. However the usage and dose of these extract which are in random and unspecified is a big challenge for acceptance as a medicine till not get standardized. The most important Ayurvedic drugs i.e. Saptavimsatika   guggulu  had been selected from Ayurvedic famous books named API Ayurvedic Monographs for Phytochemical and Physicochemical study. This Ayurvedic drugs is mainly and commonly used in the treatment of heart, skin and stomach related disease. Drug preparation was done during an event organized by our University under theme Rx-Thon.


Methods: Physico and Phytochemical study both had been done in the labs of  School of Pharmacy, Graphic Era Hill University. Values like Exractive value, Ash value, Mosture content, pH values, True density, bulk density, angle of repose, carr's index, hausner's ratio, Florescence analysis, TLC was covered in the study


Result: Phytochemical study revealed that reducing sugars, tannin, phenolic compounds, saponin glycosides, and gum were present in the sample. Various physico-chemical parameter had been studied in the standardization procedures. The extractive, ash values, florescence analysis was done and was compared to reference standard.


Conclusion: The physicochemical standardization of polyherbal formulation Saptavimsatika guggulu was carried out. The individual ingredients of the  formulation were authenticated and standardized as per WHO guidelines and Indian Herbal Pharmacopoeia. The in-house formulation was prepared and studied for various physicochemical properties. Although no marketed sample is available hence a porbability is made under standard evaluation parameter to launch this product in market for sale.

Keywords: Ayurvedic, Polyherbal Phytochemical, Saptavimsatika   guggulu

References

1. Organisation Mondiale De La Sante. Quality control methods for medicinal plant materials, Rev. Original English, World Health Organisation; 1992: 559; 159-165.
2. Ekka NR, Nmedo KP and Samal PK: Standardization strategies for Herbal drugs. Research Journal Pharm. and Tech 2008; 1: 310-312.
3. Anonymous. WHO: Quality Control Methods for Medicinal Plant Materials. AITBS Publishers, Delhi 2002: 65–67.
4. Mosihuzzamann M. Protocols on safety, efficacy, standardization and documentation of herbal medicines. IUPAC, 2008;80(10):2195-2230.
5. Anonymous, Quality Control Methods for Medicinal Plant Materials (An Authorised Publication of WHO, Geneva) New Delhi; AITBS Publishers, 2002; 65-67.
6. The Ayurvedic Formulary of India. Government of India, Ministry of Health and family welfare. New Delhi: Department of ISM and H; 2003: 2; 245-248.
7. Siddiqui, Hakim MA. Format for the pharmacopoeial analytical standards of compound formulation, workshop on standardization of Unani drugs, (appendix) New Delhi: Central Council for Research in Unani Medicine (CCRUM); 1995:4;456-458.
8. Anonymous, Indian Pharmacopoeia, Ministry of Health and Family Welfare, GOI, New Delhi, 2010;1:10-146.
9. Mukerjee PK. Quality control of herbal drugs, Business horizons pharmaceutical publisher, New Delhi, 2002:15;122-124.
10. Lachman L, Liberman HA, Kanig JL. The theory and practice of industrial Pharmacy. Varghese publishing house, Bombay; 1987:2; 145-146.
11. Wani MS. Herbal medicine and its standardization. Pharm Rev. 2007;5(6): 87-92.
12. Khandelwal K R. Practical Pharmacognosy, Techniques and Experiments. Nirali Prakashan, Pune; 1996;12: 58-59.
13. Harbone JB. Phytochemical method- a guide to modern technique of plant analysis Champman and Hall, New York; 1984: 2; 113-117.
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How to Cite
Nainwal, P. “QUALITY CONTROL EVALUATION OF IN HOUSE PREPARED POLYHERBAL AYURVEDIC FORMULATION SAPTAVIMSATIKA GUGGLU”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 12, no. 5, Apr. 2019, pp. 317-20, https://innovareacademics.in/journals/index.php/ajpcr/article/view/32952.
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Original Article(s)