AN EVALUATION ON PRESCRIBING PATTERN OF ANTIBIOTICS IN PAEDIATRIC INPATIENTS AT TERTIARY CARE HOSPITAL

  • SABISHRUTHI S Department of Pharmacy Practice, Jaya College of Paramedical Sciences, College of Pharmacy, Chennai, Tamil Nadu, India.
  • KAVITHA S Department of Pharmacy Practice, Jaya College of Paramedical Sciences, College of Pharmacy, Chennai, Tamil Nadu, India.
  • JAGAN NATHAN B Department of Pharmacy Practice, Jaya College of Paramedical Sciences, College of Pharmacy, Chennai, Tamil Nadu, India.
  • KALICHETI PRIYANKA Department of Pharmacy Practice, Jaya College of Paramedical Sciences, College of Pharmacy, Chennai, Tamil Nadu, India.
  • ARSHATH A Department of Pharmacy Practice, Jaya College of Paramedical Sciences, College of Pharmacy, Chennai, Tamil Nadu, India.

Abstract

Objective: Our objective of the study was to evaluate the prescribing patterns of drugs with cost analysis in pediatric inpatients at tertiary care hospital.


Methods: It is an observational prospective study carried out in pediatric inpatients with a sample of 180 patients based on age, inclusion, and exclusion criteria for period of 3 months. The patient’s data were collected using patient case record form and analysis of the data was done.


Results: Of 180 patients data were collected, the results show that majority of gender admitted in the hospital were male children 94 (52%) and many are from age group of early childhood (2–5 years) 67 (37%). Respiratory tract infections are diagnosis most commonly analyzed and off overall 236 prescribed antibiotics cephalosporins 86 (43%) and combination of amoxicillin + clavulanic acid 25 (71%) is the class of antibiotics prescribed higher than other class of drugs. Parental 173 (73%) route of administration was observed to be followed more than other route. The percentage of cost variation of antibiotics observed in the study reveals that the huge variations were seen in the cost of medication in maximum and minimum cost.


Conclusion: The present study reveals that the prescribed antibiotics were as per the diagnosis of the patient and not by proceeding proper culture sensitivity testing. Hence, awareness about antibiotic must be created among practicing physicians to increase the therapeutic compliance of the patient.

Keywords: Pediatrics, Antibiotics, Prescribing, Culture sensitivity test, Awareness

References

1. Choudhury DK, Bezbaruah BK. Antibiotic prescriptions pattern in paediatric inpatient department Gauhati medical college and hospital, Guwahati. J Appl Pharm Sci 2013;3:144-8.
2. Al-Ghazali MA, Alakhali KM, Alawdi S. Study of antibiotics prescribing pattern in paediatric patients of Thamar province, in republic of Yemen. J Appl Pharm 2017;9:1-4.
3. Pradeepkumar B, Alameri T, Narayana G, Reddy YP, Ramaiah JD. Assessment of antibiotic prescribing pattern in pediatric patients: A cross sectional hospital-based survey. J Health Res 2017;4:235 7.
4. Malpani AK, Waggi M, Rajbhandari A, Kumar GA, Nikitha R, Chakravarthy AK. Study on prescribing pattern of antibiotics in a pediatric out-patient department in a tertiary care teaching and non teaching hospital. Indian J Pharm Pract 2016;9:253-9.
5. Arnold SR, Allen UD, Al-Zahrani M, Tan DH, Wang EE. Antibiotic prescribing by pediatricians for respiratory tract infection in children. Clin Infect Dis 1999;29:312-7.
6. Zuppa A, Vijayakumar S, Jayaraman B, Patel D, Narayan M, Vijayakumar K, et al. An informatics approach to assess pediatric pharmacotherapy: Design and implementation of a hospital drug utilization system. J Clin Pharmacol 2007;47:1172-80.
7. Kanish R, Gupta K, Juneja S, Bains H, Kaushal S. Prescribing pattern of antibiotics in the department of pediatrics in a tertiary care medical college hospital in Northern India. Asian J Med Sci 2014;5:69-72.
8. Narayan DS, Mangesh MM. A study of prescription pattern of antibiotics in paediatric in patients at a tertiary care hospital in central India. Int J Pharmacol Res 2016;6:286-90.
9. Leung E, Weil DE, Raviglione M, Nakatani H; World Health Organization World Health Day Antimicrobial Resistance Technical Working Group. The WHO policy package to combat antimicrobial resistance. Bull World Health Organ 2011;89:390-2.
10. Suman RK, Ray IM, Mohanty NC, Mukhia RK, Deshmukh YA. Assessment of usage of Antibiotic and their pattern of antibiotic sensitivity test among childhood fever. Int J Pharm Pharm Sci 2014;6:296-9.
11. Khanam US, Masud KN, Khurshed T, Chakma U. Antibiotics prescription pattern in rural area of Bangladesh: A cross-sectional study in Debidwar Upazila of Comilla district. Int J Pharm Pharm Sci 2018;10:36-40.
12. Gupta N, Safhi MM, Sumaily JM, Agarwal M. Drug prescribing patterns in children registered in the department of pediatrics of Jizan general hospital of Jizan, KSA. Int J Pharm Pharm Sci 2013;5:397-9.
13. Resi D, Milandri M, Moro ML, Romagna E. Antibiotic prescriptions in children. J Antimicrob Chemother 2003;52:282-6.
14. Rad LV, Alekhya M. Prescribing pattern of antibiotics in pediatric inpatient department of a tertiary care teaching hospital in Bangalore. IOSR J Pharm Biol Sci 2015;10:26-32.
15. de Bie S, Kaguelidou F, Verhamme KM, De Ridder M, Picelli G, Straus SM, et al. Using prescription patterns in primary care to derive new quality indicators for childhood community antibiotic prescribing. Pediatr Infect Dis J 2016;35:1317-23.
16. Piseh HN, Padwal SL, Jadhav RR, Deshmukh VS, Jadhav AD, Kolhe AM. Drug prescribing and dispensing pattern in pediatrics outpatient clinic of a rural tertiary-care teaching hospital. Natl J Physiol Pharm Pharmacol 2015;5:313-7.
17. Venkateswaramurthy N, Faisal EM, Sambathkumar R. Assessment of drug prescription pattern in paediatric patients. J Pharm Sci Res 2017;9:81-4.
18. Jagan Nathan B, Sabishruthi S, Kavitha S, Sindhu S, Punitha S. An outlook on cost analysis among common oral antihypertensive medications of various brands available in Indian pharmaceutical companies. J Med Sci Clin Res 2019;7:89-95.
19. Purbandini CS, Sauriasari R. Cost-effectiveness analysis of ceftriaxone and non-ceftriaxone on typhoid fever patients. Int J App Pharm 2018;10:87-91.
20. Naveen V, Siddiq A, Chandana G. A study on drug utilization pattern of cephalosporins in general medicine and surgical inpatient department. Int J Curr Pharm Res 2018;10:33-6.
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SABISHRUTHI S, KAVITHA S, JAGAN NATHAN B, KALICHETI PRIYANKA, and ARSHATH A. “AN EVALUATION ON PRESCRIBING PATTERN OF ANTIBIOTICS IN PAEDIATRIC INPATIENTS AT TERTIARY CARE HOSPITAL”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 12, no. 12, Oct. 2019, pp. 53-57, doi:10.22159/ajpcr.2019.v12i12.35074.
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