AN EVALUATION ON PRESCRIBING PATTERN OF ANTIBIOTICS IN PAEDIATRIC INPATIENTS AT TERTIARY CARE HOSPITAL
Background: Antibiotics are the class of drugs which plays a vital role in prescribing patterns of patients. Hence, our current study was aimed to evaluate the prescribing patterns of drugs with cost analysis in paediatric inpatients at Tertiary care hospital. Methods: It is an observational prospective study carried out in paediatric inpatients with a sample of 180 patients based on age, inclusion and exclusion criteria for period of 3 months. The patient’s data were collected using patient case record form (CRF) and analysis of the data was done. Results: Out of 180 patients data were collected, the results shows that majority of gender admitted in the hospital were male children 94(52%) and many are from age group of early childhood (2-5 years) 67(37%). Respiratory tract infections are diagnosis most commonly analysed and off overall 236 prescribed antibiotics Cephalosporin 86 (43%) and combination of Amoxicillin + Clavulanic acid 25 (71%) are the class of antibiotics prescribed higher than other class of drugs. Parental 173 (73%) route of administration was observed to be followed more than other route. The percentage of cost variation of antibiotics observed in the study reveals that the huge variations were seen in the cost of medication in maximum and minimum cost. Conclusion: The present study reveals that the prescribed antibiotics were as per the diagnosis of the patient and not by proceeding proper culture sensitivity testing. Hence, awareness about antibiotic must be created among the practicing physicians to increase the therapeutic compliance of the patient.
1. Choudhury DK, Bezbaruah BK. Antibiotic prescriptions pattern in paediatric Inpatient Department Gauhati Medical College and Hospital, Guwahati. J App Pharm Sci. 2013; 3(8): 144-8.
2. Al-Ghazali MAA , Alakhali KM, and Alawdi S. Study of Antibiotics Prescribing Pattern in Paediatric Patients of Thamar Province, in Republic of Yemen. J Appl Pharm 2017; 9(3).
3. Pradeepkumar B, Alameri T, Narayana G, Reddy Y.P, Ramaiah J.D. Assessment of Antibiotic Prescribing Pattern in Pediatric Patients:A Cross-sectional Hospital-based Survey. Journal of Health and Research, oct-dec 2017; 4(4): 235-237
4. Malpani A.K, Waggi M, Rajbhandari A, Kumar G.A, Nikitha R, Chakravarthy A.K, Study on Prescribing Pattern of Antibiotics in a Pediatric Out-Patient Department in a Tertiary Care Teaching and Non-Teaching Hospital. Indian Journal of Pharmacy Practice. Oct-Dec 2016; 9(4).
5. Arnold SR, Allen UD, Al-Zahrani M, Tan DH, Wang EE. Antibiotic prescribing by pediatricians for respiratory tract infection in children. Clin Infect Dis. 1999; 29(2): 312-7.
6. Zuppa A, Vijaykumar S, Jayaraman B, Patel D, Narayan M,Vijaykumar K, et al. An informatics approach to assess paediatric pharmacotherapy: Design and implementation of a hospital drug utilisation system. J Clin Pharmacol 2007; 47: 1172?1180.
7. Kanish R, Gupta K, Juneja S, H.S. Bains , Kaushal S, Prescribing pattern of antibiotics in the department of pediatrics in a tertiary care medical college hospital in Northern India, Asian Journal of Medical Sciences Oct-Dec 2014; 5(4): 69-72.
8. Choudhury DK and Bezbaruah BK, Antibiotic Prescriptions Pattern in Paediatric In-Patient Department Gauhati Medical College and Hospital, Guwahati, Journal of Applied Pharmaceutical Science. Aug 2013; 3(08): 144-148.
9. Narayan DS and Mangesh MM. A Study of Prescription Pattern of Antibiotics in Paediatric InPatients at a tertiary care hospital in central India. International Journal of Pharmacological Research. 2016; 6(08): 286-290.
10. Emily L, Diana WE, Mario R, Hiroki N. The WHO policy package to combat antimicrobial resistance. Bulletin of the WHO. 2011; 89: 390-392.
11. Gupta N, Safhi MM, Sumaily JMY, Agarwal M. Drug Prescribing Patterns In Children Registered In The Department Of Pediatrics Of Jizan General Hospital Of Jizan, KSA. Int J Pharm Pharm Sci. 2013; 5(4): 397-399.
12. D. Resi, M. Milandri, M. L. Moro and the Emilia Romagna. Antibiotic prescriptions in children. Journal of Antimicrobial Chemotherapy. 2003; 52: 282–286.
13. Rad LV, Alekhya M. Prescribing Pattern of Antibiotics in Pediatric Inpatient Department of a Tertiary Care Teaching Hospital in Bangalore. IOSR Journal of Pharmacy and Biological Sciences. (Jul - Aug. 2015); 10(4): 26-32.
14. De Bie et al, Using?Prescription?Patterns?in?Primary?Care?to?Derive?New? Quality?Indicators?for?Childhood?Community?Antibiotic?Prescribing. The Pediatric Infectious Disease Journal. December?2016; 35(12): 1317–1323.
15. Pise HN, Padwal SL, Jadhav RR, Deshmukh VS, Jadhav AD, Kolhe AM. Drug prescribing and dispensing pattern in pediatrics outpatient clinic of a rural tertiary-care teaching hospital. Natl J Physiol Pharm Pharmacol. 2015; 5: 313-317.
16. Venkateswaramurthy.N, Faisal. EM and Sambathkumar. R. Assessment of Drug Prescription Pattern In Paediatric Patients. J. Pharm. Sci. & Res. 2017; 9(2): 81-84.
17. Jagan Nathan JB, S. Sabishruthi, S. Kavitha, S. Sindhu, S.Punitha. An Outlook on Cost Analysis among Common Oral Antihypertensive Medications of various Brands Available in Indian Pharmaceutical Companies. Journal of Medical Science and Clinical Research. 2019; 07(07): 89-95.
This work is licensed under a Creative Commons Attribution 4.0 International License.
The publication is licensed under CC By and is open access. Copyright is with author and allowed to retain publishing rights without restrictions.