DRUG UTILIZATION STUDY AMONG GERIATRIC PATIENTS IN A TERTIARY CARE TEACHING HOSPITAL IN SOUTH INDIA
Objectives: The objective of our study is to evaluate the drug utilization pattern among geriatric patients in a tertiary care teaching hospital in south India & analyse the prescription pattern.
Methods: Retrospective medical record analysis was performed for indoor cases of the geriatric patients (aged ≥65 years) admitted in medicine wards of Raichur institute of medical sciences (RIMS) teaching hospital, Raichur from June 2015 to May 2016. They were analyzed for demographics, indications for admission, various systems involved, duration of hospital stay, various drugs prescribed. Analysis of drugs used was done using the world health organization (WHO) prescribing indicators.
Results:The majority of patients were found to be in the age group of 65 to 70 years (70.25%).It was noticed that females (51.75%) were more compared to males (48.25 %). The drugs prescribed were analysed. Ranitidine, ceftriaxone, theophylline, salbutamol were prescribed to majority of the patients in this study group. The average number of drugs per prescription was 7.42. Drugs prescribed by generic name were 33.62%. Among the drugs prescribed, 88.69% were from the national list of essential medicines (NLEM). This study revealed the chronic nature of diseases affecting the geriatric population with an increased incidence of cardiovascular diseases (32.5%) & respiratory diseases (32.25%). The pattern of drug prescription also showed a trend towards polypharmacy (7.42), which has to be viewed with caution given the pharmacokinetic changes in the elderly. These studies can help to promote rational usage of drugs.
Conclusion: To conclude, this study provided insights into the patterns of drug use in our tertiary hospital on geriatric patients as well as various diseases prevalent among geriatric patients. Widespread polypharmacy, high use of antibiotics & injections, lack of generic prescribing are some concerns that need to be addressed to promote rational usage of drugs.
Keywords: Geriatrics, drug utilization, WHO prescribing indicators, polypharmacy.
1. Lourdu Jafrin A, Venkata Naveen Kumar P, Udhayalakshmi T, Jayapriya B and Maruti. Drug utilization patterns of geriatric patients admitted in the medicine department of a tertiary care hospital. Int. J. of Pharm. & Life Sci 2013; 4: 3087-92.
2. Binit NJ, Tejas KP, Manish JB, Tripathi CB. Drug utilization pattern and pharmacoeconomic analysis in geriatric medical in patients of a tertiary care hospital of India. Journal of Pharmacology and Pharmacotherapeutics 2014; 5:15-20.
3. Battula P, Thandlam MR, Thammisetty DP, Ranganayakulu D. A Prospective Study on inappropriate drug utilization in geriatric patients at a tertiary care teaching hospital. Indian Journal of Pharmacy Practice 2016; 9: 178-84.
4. Gurudeo NS, Neeraj K, Prashant M. To assess the drug utilization pattern and to analyze pharmacoeconomics for geriatrics in-patient in medicine department of tertiary care teaching hospital. World journal of pharmacy and pharmaceutical sciences 2017; 6:2675-88.
5. Nayaka SR, Rajeshwari B, Venkatadri TV. Drug utilization pattern in geriatric inpatients of medicine department in a tertiary care teaching hospital. Int J Basic Clin Pharmacol 2015; 4:568-73.
6. Ramanath KV, Nedumballi S. Assessment of medication-related problems in geriatric patients of a rural tertiary care hospital. Journal of young pharmacists 2012; 4:273-8.
7. Pradhan S, Panda A, Mohanty M, Behera JP, Ramani YR, Pradhan PK. A study of the prevalence of potentially inappropriate medication in elderly in a tertiary care teaching hospital in the state of Odisha. Int J Med Public Health 2015; 5:344-8.
8. Burla S. “Pattern of medication use among elderly patients attending medicine department in a tertiary care hospital in India”. Asian Journal of Pharmaceutical and Clinical Research 2016; 9: 266-9.
9. John NN, Kumar A. A study on polypharmacy in senior indian population. International journal of pharmaceutical, chemical and biological sciences 2013; 3:168-71.
10. Goudanavar P, Keerthi Y, John SE, Jacob J, Krishna MS. A prospective study on medication prescribing pattern for geriatric patients in a tertiary care teaching hospital .Asian journal of biomedical and pharmaceutical sciences 2016;6:23-7.
11. Abraham F, Varughese G, Mathew JC, John PM, Sam GK. Drug utilization pattern among geriatric patients in a tertiary care teaching hospital. Asian Journal of Pharmacology and Clinical Research 2015; 8:191-4.
12. Sharma N, Advani U, Kulshreshtha S, Parakh R, Bansal A, Sinha RR. Screening of prescriptions in geriatric population in a tertiary care teaching hospital in north India. The Journal of Phytopharmacology 2013; 2: 38-45.
13. Binod R, Sushil K, Kripa T, Kumar KA. Drug utilization pattern in geriatric patients admitted in the medicine department at tertiary care hospital. Indian Journal of Basic and Applied Medical Research 2017; 7:36-44.
14. Borah L, Devi D, Debnath PK and Deka D. “A study of drug utilization pattern of the geriatric patients in the department of geriatric medicine in a tertiary care hospital in assam, India”. Asian Journal of Pharmaceutical and Clinical Research 2017; 10:122-6.
15. Jadhav RR, Jadhav AD, Padwal SL, Kale AS, Pise HN. Drug utilization pattern in geriatric out patient in tertiary care hospital. Int J Basic Clin Pharmacol 2017; 6:2078-81.
16. Balaji V, Aithal S, Geetha S, Swetha ES. “Drug utilization pattern among geriatric patients admitted in medical intensive care unit in a tertiary care teaching hospital”. Asian Journal of Pharmaceutical and Clinical Research 2015; 8:281-3.
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