CHEMICAL CONSTITUENTS AND PHARMACOLOGICAL ACTIVITIES OF LANTANA CAMARA – A REVIEW

  • ALI ESMAIL AL-SNAFI Department of Pharmacology, Thi-Qar College of Medicine, Nasiriyah, Iraq.

Abstract

Objective: The review was designed to investigate the traditional uses, chemical constituents and pharmacological effects of Lantana camara.


Methods: In the current review, databases including Web Science, Pub Med, Scopus and Science Direct, were searched to investigate the chemical constituents and pharmacological effects of Lantana camara.


Results: The plant contained alkaloids, glycosides, steroids, saponins, flavanoids, coumarins, tannins, carbohydrates, hydroxy anthraquinones, anthraquinone glycosides, proteins, phytosteroids, fixed oils, fats, and triterpinoids. Previous pharmacological studies revealed that Lantana camara possessed antimicrobial, antiparasitic, anxiolytic, gastrointestinal, hypoglycemic, cardiovascular, antioxidant, anticancer, antiinflammatory, analgesic, wound healing, antiurolithiatic, hepatoprotective, reproductive, anti–hemorrhoidal, thrombin inhibition and many other effects.


Conclusion: Lantana camara represents a promising medicinal plant with a wide range of pharmacological activities that could be utilized in several medical applications because of its effectiveness and safety.

Keywords: constituents, pharmacology, Lantana camara

References

1. Al-Snafi AE. Chemical constituents and pharmacological activities of milfoil (Achillea santolina). A review. Int J Pharm Tech Res 2013;5:137377.
2. Al-Snafi AE. The pharmaceutical importance of Althaea officinalis and Althaea rosea: A review. Int J Pharm Tech Res 2013;5:1387-5.
3. Al-Snafi AE. The pharmacological importance of Anethum graveolens. A review. Int J Pharm Pharm Sci 2014;6:11-3.
4. Al-Snafi AE. The pharmacology of Anchusa italica and Anchusa strigosa. A review. Int J Pharm Pharm Sci 2014;6:7-10.
5. Al-Snafi AE. Pharmacological and therapeutic importance of Hibiscus sabdariffa. A review. Int J Pharm Res 2018;10:451-75.
6. Al-Snafi AE. Immunological effect of medicinal plants. A review (Part 2). Immun Endoc Metab Agents Med Chem 2016;16:100-21.
7. The Plant List, Lantana camara. Available from: http://www. theplantlist.org/tpl/record/kew-107934.
8. ITIS, Lantana camara. Available from: https://www.itis.gov/servlet/ SingleRpt/SingleRpt?search_topic=TSN&search_value=32175.
9. Ganatra SH, Gurubaxani BS. Preliminary phytochemical and TLC profiling of Lantana camara leaf extracts. J Chem Pharma Res 2016;8:614-7.
10. Fattah NF. Extraction of Lantana camara for Wound Healing Application. Bachelor Thesis in Chemical Engineering, Faculty of Chemical and Natural Resources Engineering, University of Malaysia; 2013.
11. Asija R, Kumar V, Sharma AK. Hepatoprotective activity of Lantana camera against carbon tetrachloride induced hepatotoxicity in Wister rat. Int J Pharm Erudition 2015;4:1-7.
12. Dua VK, Pandey AC, Dash AP. Adulticidal activity of essential oil of Lantana camara leaves against mosquitoes. Indian J Med Res 2010;131:434-9.
13. Sastri BN. The Wealth of India. New Delhi, India: CSIR; 1962.
14. Verma SC, Jain CL, Nigam S, Padhi MM. Rapid extraction, isolation, and quantification of oleanolic acid from Lantana camara roots using microwave and HPLC-PDA techniques. Acta Chromatogr 2013;25:181-99.
15. Dharmagada VS, Tandonb M, Vasudevan P. Biocidal activity of the essential oils of Lantana camara, Ocimum sanctum and, Tagetes patula. J Sci Ind Res 2005;64:53-6.
16. Barreto F, Sousa E, Campos A, Costa J, Rodrigues F. Antibacterial activity of Lantana camara Linn and Lantana montevidensis brig extracts from cariri-ceará, brazil. J Young Pharm 2010;2:42-4.
17. Pradhan RR, Hati DK, Samal S. Pharmacognostical phytochemical and antimicrobial studies on the leaves of Lantana camara. Pharm Lett 2012;4:1648-56.
18. Venkatachalam T, Kumar VK, Selvi PK, Maske AO, Kumar NS. Physico-chemical and preliminary phyto-chemical studies on the Lantana camara fruits. Int J Pharm Pharm Sci 2011;3:52-4.
19. Bhatia N, Singh K, Shorey G, Singh G, Dhawan R. Evaluation of contact spermicidal potential of Lantana camara leaf extracts on human spermatozoa. Int J Reprod Contracept Obstet Gynecol 2016;5:3935-47.
20. Salada JT, Balala LM, Vasquez EA. Phytochemical and antibacterial studies of Lantana camara L. leaf fraction and essential oil. Int J Sci Res Publ 2015;5:1-5.
21. Ganjewala D, Sam S, Hayat K. Biochemical compositions and anti-bacterial activities of Lantana camara plants with yellow lavender, red and white flowers. Eurasia Jour BioSci 2009;3:69-77.
22. Asadu C, Anosike C, Uzoegwu P, Abonyi O, Ezugwu A, Uroko R. In vitro antioxidant activity of methanol extract of Lantana camara leaves. Glob Vet 2015;14:595-602.
23. Begum S, Wahab A, Siddiqui B, Qamar F. Nematicidal constituents of the aerial parts of Lantana camara. J Nat Prod 2000;63:765-7.
24. Zoubiri SI, Baaliouamer AI. Chemical composition and insect-cidal properties of Lantana camara leaf essential oils from Algeria. J Essent Oil Res 2012;24:377-83.
25. Mariajancyrani J, Chandramohan GS, Brindha P, Saravanan PS. GC MS analysis of terpenes, from hexane extract of Lantana camara leaves. IJAPBC 2014;3:37-41.
26. Murugesan S, Rajeshkannan C, Suresh BD, Sumathi R, Manivachakam P. Identification of insect-cidal properties in common weed-Lantana camara Linn by gas chromatography and mass spectrum (GC-MS-MS). Adv Appl Sci Res 2012;3:2754-9.
27. Murugesan S, Senthilkumar N, Babu DS, Rajasugunasekar D. Chemical constituents and toxicity assessment, of the leaf oil of Lantana camara, from Tamilnadu regions. Asian J Plant Sci Res 2016;6:32-42.
28. Zandi-Sohani N, Hojjati M, Carbonell-Barrachina AA. Bioactivity of Lantana camara L. Essential oil against Callosobruchus maculatus (Fabricius). Chil J Agric Res 2012;72:502-6.
29. Kurade N, Jaitak V, Kaul V, Sharma O. Chemical composition, and anti-bacterial activity of essential oils of Lantana camara, Ageratum houstonianum and Eupatorium adenophorum. Pharm Biol 2010;48:539-44.
30. Begum S, Wahab A, Siddiqui BS. Pentacyclic triterpenoids from the aerial parts of Lantana camara. Chem Pharm Bull (Tokyo) 2003;51:134-7.
31. Sharma OP, Dawra RK, Makkar HP. Isolation and partial purification of lantana (Lantana camara L.) toxins. Toxicol Lett 1987;37:165-72.
32. Shamsee ZR, Al-Saffar AZ, Al-Shanon AF, Al-Obaidi JR. Cytotoxic and cell cycle arrest induction of pentacyclic triterpenoides separated from Lantana camara leaves against MCF-7 cell line in vitro. Mol Biol Rep 2019;46:381-90.
33. Qamar F, Begum S, Raza S, Wahab A, Siddiqui B. Nematicidal natural products, from the aerial parts of Lantana camara Linn. Natural Product Res Formerly Natural Prod Lett 2005;19:609-13.
34. Begum S, Zehra SQ, Ayub A, Siddiqui BS. Anew 28-noroleanane triterpenoid from the aerial parts of Lantana camara. Nat Prod Res 2010;24:1227-34.
35. Ali AA, Elgimabi ME. Extraction and determination of antioxidants, polyphenols, flavonoids and antioxidants activity in some plants. Int J Chem Sci 2015;13:1883-92.
36. Mani LM, Sankar C, Dilip C, Azeem AK, Raj D, Mathew L, et al. Antimicrobial studies on extracts of Lantana camara. Linn. Pharm Lett 2010;2:80-2.
37. Oyedara OO. Evaluation of the in vitro Antimicrobial Activities and Phytochemial Compounds of the Leaf Extracts of Lantana Camara Linn. MSc Thesis, Department of Microbiology, Obafemi Awolowo University, 2010.
38. Saraf A, Quereshi S, Sharma K, Khan NA. Antimicrobial activity of Lantana camara L. J Exp Sci 2011;2:50-4.
39. Naz R, Bano A. Phytochemical screening anti-oxidants and anti-microbial potential of Lantana camara in different solvents. Asian Pac J Trop Dis 2013;3:480-6.
40. Pradeep BV, Tejaswini M, Nishal P, Pardhu G, Shylaja S, Kumar KC. Phytochemical screening and antimicrobial activities of plant extract of Lantana camara. J Environ Biol 2013;34:645-9.
41. Onywere G, Gyles P, Lewin J, Bandoo T, Mundell K, Bailey D, et al. A Jamaican study: In vitro comparison of the effects of Lantana camara, Gouania lupuloides and commercial mouth washes on oral microorganisms. Am J Public Health Res 2016;4:128-33.
42. Patil Shriniwas P, Kumbhar Subhash T. Antioxidant, antibacterial and cytotoxic potential of silver nanoparticles synthesized using terpenes rich extract of Lantana camara L. leaves. Biochem Biophys Rep 2017;10:76-81.
43. Sharma B, Kumar P. Bioefficacy of Lantana camara L. Against some human pathogens. Indian J Pharm Sci 2009;71:589-93.
44. Ruhela S, Shrivastava V, Mathur A. Study of antimicrobial activity of solvent extract of leaves of Lantana camara. Eur J Pharm Med Res 2017;4:668-72.
45. Kirimuhuzya C, Waako P, Joloba M, Odyek O. The anti-mycobacterial activity of Lantana camara a plant traditionally used to treat symptoms of tuberculosis in South-Western Uganda. Afr Health Sci 2009;9:40-5.
46. Swamy MK, Sinniah UR, Akhtar MS. In vitro pharmacological activities and GC-MS analysis of different solvent extracts of Lantana camara leaves collected from tropical region of Malaysia. Evid Based Complement Alternat Med 2015;2015:506413.
47. Fayaz M, Bhat MH, Fayaz M, Kumar A, Jain AK. Antifungal activity of Lantana camara leaf extracts in different solvents against some pathogenic fungal strains. Pharmacologia 2017;8:105-12.
48. Sharma B, Kumar P, Joshi SC. Topical treatment of dermatophytic lesion on mice (Mus musculus) model. Indian J Microbiol 2011;51:217-22.
49. Ngwewondo A, Wang M, Manfo FPT, Samje M, Ganin’s JN, Ndi E, et al. Filaricidal properties of Lantana camara and tamarindus indica extracts, and lantadene A from L. Camara against onchocerca ochengi and loa loa. PLoS Negl Trop Dis 2018;12:e0006565.
50. Misra N, Sharma M, Raj K, Dangi A, Srivastava S, Misra- Bhattacharya S, et al. Chemical constituents and antifilarial activity of Lantana camara against human lymphatic filariid Brugia malayi and rodent filariid Acanthocheilonema viteae maintained in rodent hosts. Parasitol Res 2007;100:439-48.
51. Kamatchi PA, Maheswaran R, Ignacimuthu S. Evaluation of larval toxicity of Lantana camara L. and Catharanthus roseus L. against Culex quinquefasciatus say and Aedes Aegypti L. Entomol Ornithol Herpetol 2016;5:1.
52. Macedo IT, Bevilaqua CM, de Oliveira LM, Camurça-Vasconcelos AL, Morais SM, Machado LK, et al. In vitro activity of Lantana camara, Alpinia zerumbet, Mentha villosa and Tagetes minuta decoctions on Haemonchus contortus eggs and larvae. Vet Parasitol 2012;190:504-9.
53. Rajan DS, Varghese TA. An evaluation on the larvicidal efficacies of aqueous leaf extracts of Lantana camara and Catharanthus roseus against mosquito larvae. Int J Mosq Res 2017;4:93-7.
54. Patel J, Kumar GS, Deviprasad SP, Deepika S, Qureshi S. Phytochemical and anthelmintic evaluation of Lantana camara var aculeate leaves against Pheretima posthuma. J Glob Trends Pharm Sci 2011;2:11-20.
55. Raj SN, ZailaniI AA. Effect of Lantana camara Leaves Extract on the Mortality of Musca domestica Larvae. Available from: http://www. ukm.my/permatapintar/wp-content/uploads/2014/05/PAPERS-FSC-Final.pdf.
56. Llorera DA, Lugo LO, Macatangay MR, Magpantay JC, Ogbuji CC, Sheshe NM. Lantana camara leaf extract a prospective organic mosquito larvicide. CAM Res J 2014;2:96-111.
57. Murugesan S, Rajeshkannan C, Babu DS, Sumathi R, Manivachakam P. Identification of insecticidal properties in common weed Lantana camara Linn by gas chromatography and mass spectrum (GC-MS-MS). Adv Appl Sci Res 2012;3:2754-9.
58. Dua VK, Gupta NC, Pandey AC, Sharma VP. Repellency of Lantana camara (Verbenaceae) flowers against Aedes mosquitoes. J Am Mosq Control Assoc 1996;12:406-8.
59. Dua VK, Pandey AC, Singh R, Sharma VP, Subbarao SK. Isolation of repellent ingredients from Lantana camara (Verbenaceae) flowers and their repellency against Aedes mosquitoes. J Appl Entomol 2003;27:509-11.
60. Keziah EA, Nukenine EN, Danga SP, Younoussa L, Esimone CO. Creams formulated with Ocimum gratissimum L. And Lantana camara L. Crude extracts and fractions as mosquito repellents against Aedes aegypti L. (Diptera: Culicidae). J Insect Sci 2015;15:45.
61. Bhargava S, Agrawal DD, Agrawal OP. Repellent activity of essential oil and leaf extract of Lantana camara L. In laboratory condition. Int J Theor Appl Sci 2013;5:170-4.
62. Ghodake PP, Kulkarni AS, Aloorkar NH, Osmani RA, Bhosale RR, Harkare BR, et al. In vitro anti-spasmodic activity analysis of methanolic leaves extract of Lantana camara on excised rat ileum. J Pharmacogn Phytochem 2013;2:66-71.
63. Sagar L, Sehgal R, Ojha S. Evaluation of antimotility effect of Lantana camara L. Var. Acuelata constituents on neostigmine induced gastrointestinal transit in mice. BMC Complement Altern Med 2005;5:18.
64. Tadesse E, Engidawork E, Nedi T, Mengistu G. Evaluation of the anti-diarrheal activity of the aqueous stem extract of Lantana camara Linn (Verbenaceae) in mice. BMC Complement Altern Med 2017;17:190.
65. Mengistu G. Evaluation of the Anti-diarrheal Activity of 80% Methanol Extract and Solvent Fractions of the Leaves of Lantana camara L. (Verbenaceae) in Mice. MSc Thesis, School of Graduate Studies, Addis Ababa University; 2015.
66. Sathish R, Vyawahare B, Natarajan K. Antiulcerogenic activity of Lantana camara leaves on gastric and duodenal ulcers in experimental rats. J Ethnopharmacol 2011;134:195-7.
67. Ayub A, Tauseef S, Ali ST, Begum S, Siddiqui BS, Ahmed A. Anti-oxidant activity of the medicinal plant Lantana camara L. Fuuast J Biol 2017;7:227-30.
68. Kumar S, Sandhir R, Ojha S. Evaluation of antioxidant activity and total phenol in different varieties of Lantana camara leaves. BMC Res Notes 2014;7:560.
69. Suryati AS, Kartika MZ, Aziz H. Antioxidant activity and total phenolic content of ethyl acetate extract and fractions of Lantana camara L leaf. Der Pharm Chem 2016;8:92-6.
70. Manzoor M, Anwar F, Sultana B, Mushtaq M. Variation in antioxidant and antimicrobial activities in Lantana camara L. Flowers in relation to extraction methods. Acta Sci Pol Technol Aliment 2013;12:283-94.
71. Kalita S, Kumar G, Karthik L, Rao KV. In vitro anti-oxidant and DNA damage inhibition activity of aqueous extract of Lantana camara L. (Verbenaceae) leaves. Asian Pac J Trop Biomed 2012;2:S1675-9.
72. Mahdi-Pour B, Jothy SL, Latha LY, Chen Y, Sasidharan S. Antioxidant activity of methanol extracts of different parts of Lantana camara. Asian Pac J Trop Biomed 2012;2:960-5.
73. Somanathan SS, Manikantavinay J, Devi L, Shilpa M, Hemalatha P, Raju K, et al. A comparative study on in vitro anti-oxidant activity of leaf and stem extracts of Lantana camara. Int J Novel Trend Pharm Sci 2015;5:130-4.
74. Pramod PS, Trimbakrao KS, Vanita A. Evaluation of unsaponified petroleum ether extract of Lantana camara L leaves for antioxidant activity and oxidative stability. Indian J Pharm Educ Res 2017;51:692-9.
75. Badakhshan MP, Sreenivasan S, Jegathambigai RN, Surash R. Antileukemia activity of methanolic extracts of Lantana camara. Pharmacogn Res 2009;1:274-9.
76. Pour BM, Latha LY, Sasidharan S. Cytotoxicity and oral acute toxicity studies of Lantana camara leaf extract. Molecules 2011;16:3663-74.
77. Srivastava P, Kasoju N, Bora U, Chaturvedi R. De-differentiation of leaf explants and cytotoxic activity of an aqueous extract of cell cultures of Lantana camara. Plant Cell Tiss Organ Cult 2009;99:1-7.
78. Sharma M, Sharma PD, Bansal MP. Chemopreventive effect of Lantana camara leaf extract on 7, 12-dimethylbenz [a] anthracene-induced squamous cell carcinoma of skin in Swiss albino mice. Pharm Biol 2007;45:145-8.
79. Raghu C, Ashok G, Dhanaraj SA, Suresh B, Vijayan P. In vitro cytotoxic activity of Lantana camara Linn. Indian J Pharmacol 2004;36:93-5.
80. Ghosh S, Das Sarma M, Patra A, Hazra B. Anti-inflammatory and anticancer compounds isolated from Ventilago madraspatana Gaertn. Rubia cordifolia Linn. And Lantana camara Linn. J Pharm Pharmacol 2010;62:1158-66.
81. Han EB, Chang BY, Jung YS, Kim SY. Lantana camara induces apoptosis by bcl-2 family and caspases activation. Pathol Oncol Res 2015;21:325-31.
82. Pour BM, Sasidharan S. In vivo toxicity study of Lantana camara. Asian Pac J Trop Biomed 2011;1:230-2.
83. Fatope MO, Salihu L, Asante SK, Takeda Y. Larvicidal activity of extracts and triterpenoids, from Lantana camara. Pharm Biol 2002;40:564-7.
84. Millycent SA, John MK, Kelvin JK, Piero NM, Mwaniki NE. Evaluation of analgesic, anti-inflammatory and toxic effects of Lantana camara L. Int J Phytopharmacol 2017;8:89-97.
85. Bairagi SM, Pathan IB, Nema N. Analgesic and antiinflammatory activity of crude leaf and bark extract of Lantana camara. Marmara Pharm J 2017;21:810-7.
86. Gidwani BK, Bhargava S, Rao SP, Majoomdar A, Pawar DP, Alaspure RN. Analgesic, antiinflammatory and antihemorrhoidal activity of aqueous extract of Lantana camara Linn. Res J Pharm Tech 2009;2:378-81.
87. Vyas N, Argal A. Antiurolithiatic activity of extract and oleanolic acid isolated from the roots of Lantana camara on zinc disc implantation induced urolithiasis. ISRN Pharmacol 2013;2013:951795.
88. Mayee R, Thosar A. Evaluation of Lantana camara Linn. (Verbenaceae) for antiurolithiatic and antioxidant activities in rats. Int J Pharm Clin Res 2011;3:10-4.
89. Nayak BS, Raju SS, Eversley M, Ramsubhag A. Evaluation of wound healing activity of lantana camara L. A preclinical study. Phytother Res 2009;23:241-5.
90. Dash GK, Suresh P, Ganapaty S. Studies on hypoglycaemic and wound healing activities of Lantana camara Linn. J Nat Remedies 2001;1:105-10.
91. Abdulla MA, Hassandarvish P, Ali HM, Noor SM, Mahmoud FH, Bashah NS, et al. Acceleration of wound healing potential by Lantana camara leaf extract in experimental rats. Res J Med Sci 2009;3:75-9.
92. Parwanto ML. Efficacy of Lantana camara leaf extracts ointment on dermal wound healing were infected with Staphylococcus epidermidis. Int J Basic Clin Pharmacol 2017;6:503-10.
93. Ganesh T, Sen S, Thilagam E, Thamotharan G, Loganathan T,Chakraborty R. Pharmacognostic and antihyperglycemic evaluation of Lantana camara var. Aculeate leaves in alloxan induced hyperglycemic rats. Int J Res Pharm Sci 2010;1:247-52.
94. Venkatachalam T, Kumar VK, Selvi PK, Maske AO, Anbarasan V, Kumar PS. Anti-diabetic activity of Lantana camara L fruits in normal and streptozotocin-induced diabetic rats. J Pharm Res 2011;4:1550-2.
95. de Mello FB, Jacobus D, de Carvalho KC, de Mello JR. Effects of Lantana camara (Verbenaceae) on rat fertility. Vet Hum Toxicol 2003;45:20-3.
96. Mello FB, Jacobus D, Carvalho K, Mello JR. Effects of Lantana camara (Verbenaceae) on general reproductive performance and teratology in rats. Toxicon 2005;45:459-66.
97. Kazmi I, Afzal M, Ali B, Damanhouri ZA, Ahmaol A, Anwar F, et al. Anxiolytic potential of ursolic acid derivative a stearoyl glucoside isolated from Lantana camara L. (Verbenaceae). Asian Pac J Trop Med 2013;6:433-7.
98. Matta VK, Pasala PK, Netala S, Pandrinki S, Konduri P. Anti hypertensive activity of the ethanolic extract of Lantana camara leaves on high salt loaded Wistar albino rats. Pharmacogn J 2015;7:289-95.
99. O’Neill MJ, Lewis JA, Noble HM, Holland S, Mansat C, Farthing JE, et al. Isolation of translactone-containing triterpenes with thrombin inhibitory activities from the leaves of Lantana camara. J Nat Prod 1998;61:1328-31.
100. Kumar R, Katiyar R, Kumar S, Kumar T, Singh V. Lantana camara: An alien weed, its impact on animal health and strategies to control. J Exp Biol Agric Sci 2016;4:321-37.
101. Sharma OP, Vaid J, Pattabhi V, Bhutani KK. Biological action of lantadene C, a new hepatotoxicant from Lantana camara var. Aculeata. J Biochem Toxicol 1992;7:73-9.
102. Sharma OP, Dawra RK, Pattabhi V. Molecular structure, polymorphism,and toxicity of lantadene A, the pentacyclic triterpenoid from the hepatotoxic plant Lantana camara. J Biochem Toxicol 1991;6:57-63.
103. Sharma OP, Makkar HP, Dawra RK, Negi SS. A review of the toxicity of Lantana camara (Linn) in animals. Clin Toxicol 1981;18:1077-94.
104. Sharma OP, Dawra RK, Makkar HP. Toxicity of isolated lantana (Lantana camara L) constituents to male and female guinea pigs. Vet Hum Toxicol 1989;31:10-3.
105. Garg SK, Shah MA, Garg KM, Farooqui MM, Sabir M. Antilymphocytic and immunosuppressive effects of Lantana camara leaves in rats. Indian J Exp Biol 1997;35:1315-8.
106. Seawright AA, Hrdlicka J. The oral toxicity for sheep of triterpene acids isolated from Lantana camara. Aust Vet J 1977;53:230-5.
107. Lantana Poisoning. Available from: https://www.daf.qld.gov.au/-data/ assets/pdf_file/0005/64238/IPA-Lantana-Poison-Flyer.pdf.
108. Sharma OP, Makkar HP. Lantana the fore most livestock killer in Kangra district of Himachal Pradesh. Livest Advise 1981;6:29-31.
109. Sharma OP, Makkar HP, Dawra RK. A review of the noxious plant Lantana camara. Toxicon 1988;26:975-87.
110. Sharma OP, Sharma S, Pattabhi V, Mahato SB, Sharma PD. A review of the hepatotoxic plant Lantana camara. Crit Rev Toxicol 2007;37:313-52.
111. Dwivedi SK, Shivnani GA, Joshi HC. Clinical and biochemical studies in lantana poisoning in ruminants. Indian J Anim Sci 1971;41:948-53.
112. Hussain P, Roychoudhury RK. Liver function tests in Lantana camara (L) poisoning in cattle. Indian J Vet Med 1992;12:22-33.
113. Uppal RP, Paul BS. Assessment of hepatic dys-function in experimental Lantana poisoning in sheep. Indian Vet J 1978;55:779-802.
114. Seawright AA. Studies on the pathology of experimental Lantana (Lantana camara) poisoning of sheep. Path Vet 1964;1:504-29.
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ALI ESMAIL AL-SNAFI. “CHEMICAL CONSTITUENTS AND PHARMACOLOGICAL ACTIVITIES OF LANTANA CAMARA – A REVIEW”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 12, no. 12, Oct. 2019, pp. 10-20, doi:10.22159/ajpcr.2019.v12i12.35662.
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