ISOLATION OF UROPATHOGENS AND THEIR ANTIBIOTIC SUSCEPTIBILITY PATTERN AT A TERTIARY CARE HOSPITAL IN NORTHERN INDIA.
Objective: To know the isolation rate and antibiotic susceptibility pattern of pathogens causing urinary tract infection(UTI).
Methods: A total of 500 urine samples of clinically suspected urinary tract infection were collected from January, 2019 to June 2019. The samples were inoculated on cystine lactose electrolyte deficient (CLED) agar and incubated at 37°C for 24 hrs.
Results: In our study, 303 (60.6%) samples showed growth of isolates. Among 303 isolates, 31 were Candida spp. which was not included in study. Out of 272 isolates, Escherichia coli was 31.68%, followed by Klebsiella spp. (27.72%), Enterococcus faecalis (22.44%), Citrobacter spp. (3.96%), Staphylococcus aureus (2.64%), Pseudomonas spp. (1.32%). For Gram-negative and gram-positive isolates the most effective antibiotic was nitrofurantoin.
Conclusion: The study shows Escherichia coli as the predominant pathogen that causes UTI. nitrofurantoin and fosfomycin showed very high susceptibility to uropathogens and can be used to treat primary or uncomplicated UTI.
Keywords: Urinary tract infection, Escherichia coli, Klebsiella spp., Enterococcus faecalis Nitrofurantoin, Fosfomycin.
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