DETERMINATION OF THE TOTAL PHENOLICS AND ANTIOXIDANT ACTIVITY IN THE RIND EXTRACTS OF GARCINIA MANGOSTANA L., GARCINIA COWA ROXB., AND GARCINIA ATROVIRIDIS GRIFF. EX T. ANDERS.

  • REGINA ANDAYANI Department of Pharmacy, Faculty of Pharmacy, Andalas University, Limau Manis Campus, Padang, West Sumatera, 25163, Indonesia. http://orcid.org/0000-0001-5351-6244
  • FITHRIANI ARMIN Department of Pharmacy, Faculty of Pharmacy, Andalas University, Limau Manis Campus, Padang, West Sumatera, 25163, Indonesia.
  • AINUL MARDHIYAH Department of Pharmacy, Faculty of Pharmacy, Andalas University, Limau Manis Campus, Padang, West Sumatera, 25163, Indonesia.

Abstract

Objectives: Garcinia atroviridis Griff. ex T. Anders., Garcinia mangostana L., and Garcinia cowa Roxb. are plants of the genus Garcinia that has been widely used by the community as a food flavoring, spices, and also as a herbal medicinal ingredient. This research aimed to evaluate the total phenolics and antioxidant activity from three species of Garcinia (G. atroviridis Griff. ex T. Anders., G. mangostana L., and G. cowa Roxb.)


Methods: The total phenolic content (TPC) of the extracts was estimated as Gallic Acid Equivalent by the Folin-Ciocalteu method. Antioxidant activity was assessed using Ferric Reducing Antioxidant Power assay.


Results: The TPC of G. mangostana L. rind extract is higher (31.83±3.70%), than G. cowa Roxb.(4.35±0.17%) and G. atroviridis Griff. ex T. Anders. (2.47±0.42%). Based on the antioxidant activity, G. mangostana L. rind has a higher total antioxidant activity (24.68 μmol Fe(II)/g) than G. cowa Roxb. (18.88±0.12 μM Fe (II)/g and G. atroviridis Griff. ex T. Anders.(17.61±0.05 μM Fe(II)/g).


Conclusion: The results showed that G. mangostana L rind extract contains a higher level of TPC and antioxidant activity among the other rinds. The results obtained indicate that the three samples have the potential to be a source of natural antioxidants. Further studies must be carried out to isolate compounds that have antioxidant activity.

Keywords: Total phenolic, Antioxidant activity, Garcinia atroviridis Griff. ex T. Anders., Garcinia mangostana L., Garcinia cowa Roxb

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ANDAYANI, R., F. ARMIN, and A. MARDHIYAH. “DETERMINATION OF THE TOTAL PHENOLICS AND ANTIOXIDANT ACTIVITY IN THE RIND EXTRACTS OF GARCINIA MANGOSTANA L., GARCINIA COWA ROXB., AND GARCINIA ATROVIRIDIS GRIFF. EX T. ANDERS.”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 13, no. 8, June 2020, pp. 149-52, doi:10.22159/ajpcr.2020.v13i8.36525.
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