AN OBSERVATIONAL STUDY OF CLINICAL AND HEMATOLOGICAL PROFILE OF CIRRHOSIS OF LIVER

  • BIBHU PRASAD BEHERA Department of Internal Medicine, Saheed Laxman Naik Medical College and Hospital, Koraput, Odisha, India.
  • Manoranjan Dash Department of Chest and TB, Saheed Laxman Naik Medical College and Hospital, Koraput, Odisha, India.

Abstract

Objective: Efforts can be made to normalize the hematological parameters so that the morbidity and mortality in these patients could be effectively reduced.


Methods: This observational study was carried out among 69 cirrhosis patients that fulfills the inclusion and exclusion criteria, attended the medicine outpatient department, and admitted in medicine ward of PRM Medical College and Hospital, Baripada, Dist. Mayurbhanj, Odisha, India, from June 2018 to January 2019.


Results: In our study, we had 59 male and 10 female patients with an average age of 49.8±13.19 years. About 92.75% of the patients were alcoholic. Abdominal distension (92.75%) and ascites (84.06%) were the most common presenting complaints. Pallor was present in 42 (60.87%) cases. Splenomegaly was present in 35 (50.72%) cirrhotic patients. Renal dysfunction was present in 23 (33.33%) cases. Sixty-six (95.65%) patients had anemia and 47 (68.12%) patients had thrombocytopenia.


Conclusions: From this study, we can conclude that, in cirrhosis of liver patients, various hematological changes are very common which need to be identified and corrected early to reduce morbidity and mortality.

Keywords: Cirrhosis, Anemia, Thrombocytopenia, Alcoholic, Non-alcoholic

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BEHERA, B. P., and M. Dash. “AN OBSERVATIONAL STUDY OF CLINICAL AND HEMATOLOGICAL PROFILE OF CIRRHOSIS OF LIVER”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 13, no. 4, Feb. 2020, pp. 149-52, doi:10.22159/ajpcr.2020.v13i4.36862.
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