• LOUIS COJANDARAJ Department of Medical Laboratory Sciences, Lovely Professional University, Punjab.
  • HILAL SULTAN PARA Department of Medical Laboratory Sciences, Lovely Professional University, Punjab. Email:
  • TENZIN TSEPAL Department of Medical Laboratory Sciences, Lovely Professional University, Punjab.
  • SUMAN KUMARI Department of Medical Laboratory Sciences, Lovely Professional University, Punjab.


Dengue keeps on being a significant reason for infection trouble in India, influencing the population in their typical pace of the life. Dengue in India has drastically extended in the course of the most recent couple of decades, with quickly evolving the study of disease transmission. The pervasiveness of dengue is diverse in different examinations in India, as a result of thought of a population of specific district or state at various purposes of times. The principal major dengue hemorrhagic fever episode in the whole country happened in 1996 by dengue infection serotype 2, and after a hole of very nearly 10 years, the nation confronted one more dengue fever flare-up in the year 2003 by dengue infection serotype 3. An emotional increment in the number and repeat of scenes followed, and, at present, in a huge part of the states of India, dengue is basically endemic. At present, all the four serotypes are discovered accessible for use; however, the prevalent serotype continues evolving. In spite of this pattern, observation, revealing, and conclusion of dengue remain to a great extent uninvolved in India. Progressively dynamic network-based epidemiological investigations with escalated vector control and activities for dengue immunization improvement ought to be outfitted to control the spread of dengue in India. All the distributed information related to dengue from audit of all zones of India from 2015 to 2018 is available on government official websites. Despite the fact that, the quantity of dengue cases has demonstrated a consistent ascent as time passes, the mortality has decreased. The general death pace of 1.2% in 2015 dropped to 0.25% in 2018.

Keywords: Dengue, Aedes aegypti, Aedes albopictus, Dengue virus-2, Dengue virus-3


1. Deshmukh JM, Avachat S, Fating A. Dengue with atypical manifestations and WHO classification. J Evid Based Med Healthc 2015;2:5949-65.
2. Gubler DJ. The changing epidemiology of yellow fever and dengue, 1900 to 2003: Full circle? Comp Immunol Microbiol Infect Dis 2004;27:319-30.
3. Kakkar M. Dengue fever is massively under-reported in India, hampering our response. BMJ 2012;345:e8574.
4. Chakravarti A, Arora R, Luxemburger C. Fifty years of dengue in India. Trans R Soc Trop Med Hyg 2012;106:273-82.
5. Nam VS, Yen NT, Holynska M, Reid JW, Kay BH. National progress in dengue vector control in Vietnam: Survey for Mesocyclops (Copepoda), micronecta (Corixidae), and fish as biological control agents. Am J Trop Med Hyg 2000;62:5-10.
6. Gupta E, Mohan S, Bajpai M, Choudhary A, Singh G. Circulation of dengue virus-1 (DENV-1) serotype in Delhi, during 2010-11 after Dengue virus-3 (DENV-3) predominance: A single centre hospital-based study. J Vector Borne Dis 2012;49:82.
7. Sudsom N, Techato K, Thammapalo S, Pruphetkaew N, Kongchouy N, Chongsuvivatwong V, et al. Indoor spray and windows screens effects on dengue vector density after space spraying in a field trial. Asian Pac J Trop Med 2020;13:24.
8. Bhatt S, Gething PW, Brady OJ, Messina JP, Farlow AW, Moyes CL, et al. The global distribution and burden of dengue. Nature 2013;496:504-7.
9. Wahala WM, De Silva AM. The human antibody response to dengue virus infection. Viruses 2011;3:2374-95.
10. Dar L, Broor S, Sengupta S, Xess I, Seth P. The first major outbreak of dengue hemorrhagic fever in Delhi, India. Emerg Infect Dis 1999;5:589.
11. Singh UB, Maitra A, Broor S, Rai A, Pasha ST, Seth P. Partial nucleotide sequencing and molecular evolution of epidemic causing dengue 2 strains. J Infect Dis 1999;180:959-65.
12. Mishra G, Jain A, Prakash O, Prakash S, Kumar R, Garg RK, et al. Molecular characterization of dengue viruses circulating during 2009-- 2012 in Uttar Pradesh, India. J Med Virol 2015;87:68-75.
13. Gupta E, Dar L, Narang P, Srivastava VK, Broor S. Serodiagnosis of dengue during an outbreak at a tertiary care hospital in Delhi. Indian J Med Res 2005;121:36.
14. Arunachalam N, Murty US, Kabilan L, Balasubramanian A, Thenmozhi V, Narahari D, et al. Studies on dengue in rural areas of Kurnool district, Andhra Pradesh, India. J Am Mosq Control Assoc 2004;20:87-90.
15. Change IC. The Physical Science Basis, Intergovernmental Panel on Climate Change AR4 WG1. Geneva, Switzerland: Intergovernmental Panel on Climate Change; 2013.
16. Angel B, Joshi V. Distribution and seasonality of vertically transmitted dengue viruses in Aedes mosquitoes in arid and semi-arid areas of Rajasthan, India. J Vector Borne Dis 2008;45:56.
17. Duong V, Lambrechts L, Paul RE, Ly S, Lay RS, Long KC, et al. Asymptomatic humans transmit dengue virus to mosquitoes. Proc Natl Acad Sci 2015;112:14688-93.
18. Gubler DJ, Suharyono W, Tan R, Abidin M, Sie A. Viraemia in patients with naturally acquired dengue infection. Bull World Health Organ 1981;59:623.
19. Lindsey NP, Lehman JA, Staples JE, Fischer M. Division of Vector-borne Diseases National Center for Emerging and Zoonotic Infectious Diseases CDC. West Nile virus other arboviral diseases-United States, 2013. MMWR Morb Mortal Wkly Rep 2013;63:521-6.
20. Lanciotti RS, Calisher CH, Gubler DJ, Chang GJ, Vorndam AV. Rapid detection and typing of dengue viruses from clinical samples by using reverse transcriptase-polymerase chain reaction. J Clin Microbiol 1992;30:545-51.
21. Race MW, Williams MC, Agostini CF. Dengue in the Caribbean: Virus isolation in a mosquito (Aedes pseudoscutellaris) cell line. Trans R Soc Trop Med Hyg 1979;73:18-22.
22. McBride WJ, Mullner H, LaBrooy JT, Wronski I. The 1993 dengue 2 epidemic in North Queensland: A serosurvey and comparison of hemagglutination inhibition with an ELISA. Am J Trop Med Hyg 1998;59:457-61.
23. Hunsperger EA, Yoksan S, Buchy P, Nguyen VC, Sekaran SD, Enria DA, et al. Evaluation of commercially available anti--dengue virus immunoglobulin M tests. Emerg Infect Dis 2009;15:436.
24. Brengues C, Hawkes NJ, Chandre F, McCarroll L, Duchon S, Guillet P, et al. Pyrethroid and DDT cross-resistance in Aedes aegypti is correlated with novel mutations in the voltage-gated sodium channel gene. Med Vet Entomol 2003;17:87-94.
25. Farrar J, Focks D, Gubler D, Barrera R, Guzman MG, Simmons C, et al. Towards a global dengue research agenda. Trop Med Int Health 2007;12:695-9.
26. Kay BH, Nam VS, Van Tien T, Yen NT, Phong TV, Diep VT, et al. Control of Aedes vectors of dengue in three provinces of Vietnam by use of Mesocyclops (Copepoda) and community-based methods validated by entomologic, clinical, and serological surveillance. Am J Trop Med Hyg 2002;66:40-8.
27. Rigau-Perez JG, Gubler DJ. Surveillance for dengue and dengue hemorrhagic fever. In: Dengue Dengue Hemorrhagic Fever. Oxford: CAB International; 1997. p. 405-24.
28. Vaddadi S, Vaddadi RS. Dengue fever: A review article. J Evol Med Dent Sci 2015;4:5048-58.
29. Thisyakorn U, Thisyakorn C. Latest developments and future directions in dengue vaccines. Ther Adv Vaccines 2014;2:3-9.
30. Capeding MR, Tran NH, Hadinegoro SR, Ismail HI, Chotpitayasunondh T, Chua MN, et al. Clinical efficacy and safety of a novel tetravalent dengue vaccine in healthy children in Asia: A phase 3, randomised, observer-masked, placebo-controlled trial. Lancet 2014;384:1358-65.
56 Views | 66 Downloads
How to Cite
COJANDARAJ, L., H. S. PARA, T. TSEPAL, and S. KUMARI. “DENGUE PREDOMINANCE IN INDIA: A REPORT”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 13, no. 7, May 2020, pp. 5-9, doi:10.22159/ajpcr.2020.v13i7.37602.
Review Article(s)