INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION BY AN EXTRACT OF OCIMUM BASILICUM SEEDS: AN IN-VITRO STUDY

  • PATEL RAVINDRAKUMAR K Department of Pharmacology, Indukaka Ipcowala College of Pharmacy, Anand, Gujarat, India.
  • PATEL SANDIP B Department of Pharmacology, Ramanbhai College of Pharmacy, Anand, Gujarat, India.

Abstract

Objective: Ocimum basilicum (OB) has been used to treat diverse illnesses which include urinary stone disorder for a reason that historical time in India. We investigated OB seeds for antiurolithic activity.


Methods: Calcium oxalate crystallization becomes triggered by the addition of 0.01 M sodium oxalate answers in normal human urine and nucleation was done.


Results: OB seeds were discovered to be robust and promising antiurolithiatic agents which are in accordance with its use in traditional medication.


Conclusion: An extract of the traditional herb OB has super inhibitory activity on crystalluria and therefore might be useful in dissolving urinary stone; however, in addition, a study in animal fashions of urolithiasis is needed to assess its capability antiurolithiatic interest.

Keywords: Ocimum basilicum, Urolithiasis, Calcium oxalate crystallization, Nucleation

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RAVINDRAKUMAR K, P., and P. SANDIP B. “INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION BY AN EXTRACT OF OCIMUM BASILICUM SEEDS: AN IN-VITRO STUDY”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 13, no. 9, Sept. 2020, pp. 166-9, doi:10.22159/ajpcr.2020.v13i9.37926.
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