THE PHYTOCHEMICAL SCREENING HEXANE AND METHANOL EXTRACT OF SINYO NAKAL (DURANTA REPENS)

  • PURWANTININGSIH SUGITA Department of Chemistry, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia.
  • RIZKI AMILIA Department of Chemistry, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia.
  • BUDI ARIFIN Department of Chemistry, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia.
  • DYAH UTAMI CAHYANING RAHAYU Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok, Indonesia.
  • HANHAN DIANHAR Chemistry Study Program, Faculty of Mathematics and Natural Sciences, Universitas Negeri Jakarta, Jakarta, Indonesia.

Abstract

Objective: Phytochemicals are naturally present in every part of plants range from leaves, stem bark, and fruits to roots. The use of plant-based medicine is popular among individuals and communities in developing countries. This study evaluated that the phytochemical profile of Duranta repens fruits was collected from Jombang, East Java, Indonesia.


Methods: Air-dried D. repens fruits were macerated by n-hexane and methanol, a separate flask. n-Hexane extract, then underwent saponification to remove fat. Then, the unsaponifiable of n-hexane and methanol extract was tested through phytochemical screening, respectively.


Results: The methanol extract showed the presence of alkaloids, flavonoids, tannins, and steroids, but the unsaponifiable fraction only contained steroids. The unsaponifiable fraction was found to be a mixture of hydrocarbons ranging from C13-C20, fatty acids (palmitic and linoleic acid), squalene, and Vitamin E.


Conclusion: The phytochemical screening of the plant plays an important role for pharmaceutical studies especially discovering new potential drugs for the treatment of various diseases.

Keywords: Duranta repens, Unsaponifiable hexane fraction, Methanol extract

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SUGITA, P., R. AMILIA, B. ARIFIN, D. U. C. RAHAYU, and H. DIANHAR. “THE PHYTOCHEMICAL SCREENING HEXANE AND METHANOL EXTRACT OF SINYO NAKAL (DURANTA REPENS)”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 13, no. 8, June 2020, pp. 196-00, doi:10.22159/ajpcr.2020.v13i8.38165.
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