• PURWANTININGSIH SUGITA Department of Chemistry, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia.
  • RIZKI AMILIA Department of Chemistry, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia.
  • BUDI ARIFIN Department of Chemistry, Faculty of Mathematics and Natural Sciences, IPB University, Bogor, Indonesia.
  • DYAH UTAMI CAHYANING RAHAYU Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok, Indonesia.
  • HANHAN DIANHAR Chemistry Study Program, Faculty of Mathematics and Natural Sciences, Universitas Negeri Jakarta, Jakarta, Indonesia.


Objective: Phytochemicals are naturally present in every part of plants range from leaves, stem bark, and fruits to roots. The use of plant-based medicine is popular among individuals and communities in developing countries. This study evaluated that the phytochemical profile of Duranta repens fruits was collected from Jombang, East Java, Indonesia.

Methods: Air-dried D. repens fruits were macerated by n-hexane and methanol, a separate flask. n-Hexane extract, then underwent saponification to remove fat. Then, the unsaponifiable of n-hexane and methanol extract was tested through phytochemical screening, respectively.

Results: The methanol extract showed the presence of alkaloids, flavonoids, tannins, and steroids, but the unsaponifiable fraction only contained steroids. The unsaponifiable fraction was found to be a mixture of hydrocarbons ranging from C13-C20, fatty acids (palmitic and linoleic acid), squalene, and Vitamin E.

Conclusion: The phytochemical screening of the plant plays an important role for pharmaceutical studies especially discovering new potential drugs for the treatment of various diseases.

Keywords: Duranta repens, Unsaponifiable hexane fraction, Methanol extract


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How to Cite
SUGITA, P., R. AMILIA, B. ARIFIN, D. U. C. RAHAYU, and H. DIANHAR. “THE PHYTOCHEMICAL SCREENING HEXANE AND METHANOL EXTRACT OF SINYO NAKAL (DURANTA REPENS)”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 13, no. 8, June 2020, pp. 196-00, doi:10.22159/ajpcr.2020.v13i8.38165.
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