Passiflora vitifolia Kunth is part of a group of more than 170 species of the Passifloraceae family developed in Colombia. In this study, the potential uses of the fruit peel and seed from Passiflora vitifolia collected in the Colombian Central Andes were evaluated. The physical characteristics and chemical profile of the byproducts were determined. The ethanolic extracts of these materials were used to assess the content and phytophenols composition, to establish the antioxidant potential and the likely antidiabetic activity, via in vitro inhibition of α-amylase enzyme and glucose diffusion. The performance and physico-chemical composition of seed oil were also evaluated.  P. vitifolia seeds contain almost four times more phenolic compounds (10671 mg GAE/100g sample) than the peel (2817 mg GAE/100g sample); likewise, the seeds crude protein and fat contents are higher (15.5%, and 25.6%) than the peel (6.60% and 5.70%, respectively). Nine phytoconstituents were positive for both extracts. Significant variation (p<0.05) of antioxidant and antihyperglycemic potential was observed among the peel and seeds in all methods applied. The results showed that the byproducts of P. vitifolia fruit could be used to enhance the nutritional quality of functional products. These findings were also confirmed by the ethanolic extract from seed, which revealed high levels of phenolics, exhibited high antioxidant potential and antihyperglycemic activity that make it a promising phytotherapeutic product, all of which gives added value to the fruit of this wild Passiflora.

Keywords: Passiflora vitifolia; Phenolic Compounds; Antioxidant Capacity; Antihyperglycemic activity; Colombian Andes


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Avila, J., A. Jimenez, J. Mendez, and E. Murillo. “CHEMICAL AND BIOLOGICAL POTENTIAL OF THE PASSIFLORA VITIFOLIA FRUIT BYPRODUCTS COLLECTED IN THE COLOMBIAN CENTRAL ANDES ”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 14, no. 1, Jan. 2021, pp. 182-9,
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