• PUTU DEWINTA DARMADA Department of, Wangaya Hospital, Denpasar, Indonesia.
  • DEWI CATUR WULANDARI Department of Internal Medicine, Wangaya Hospital, Denpasar, Indonesia.



diabetes mellitus, medication adherence, complication, Medication adherence rating scale-5


Objective: The prevalence of diabetes mellitus continues to increase worldwide, followed by the incidence of complications, which ends up causing morbidity and mortality in patients. There were many factors related to the incidence of complications in diabetes mellitus. Patient’s adherence to their medication is considered to have an impact on the complications in diabetic patients.

Methods: The study was conducted on 68 patients with a cross-sectional method with consecutive sampling. Statistical analysis was done using the Chi-square and Fisher’s exact test. p<0.05 was considered statistically significant. Patients were interviewed using a demographic data questionnaire and medication adherence rating scale – 5 (MARS-5). Other data and diagnosis of complications were collected through medical records. The epidemiological analysis was carried out using the prevalence ratio.

Results: There were 47 (69.1%) patients with type 2 diabetes mellitus (T2DM) hospitalized due to complications, and 56 (82.4%) patients have poor adherence to treatment. There was a significant relationship between treatment adherence and the incidence of complications in diabetes mellitus patients with p = 0.001 and it was found that there was a risk of 3.14 times in patients who have poor adherence to be hospitalized due to complications.

Conclusion: Treatment adherence affects the incidence of complications in patients with T2DM.


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How to Cite

DARMADA, P. D., and D. CATUR WULANDARI. “RELATION OF MEDICATION ADHERENCE TO THE INCIDENCE OF COMPLICATIONS IN TYPE 2 DIABETES MELLITUS PATIENTS”. Asian Journal of Pharmaceutical and Clinical Research, vol. 13, no. 12, Dec. 2020, pp. 177-81, doi:10.22159/ajpcr.2020.v13i12.39874.



Original Article(s)