SINGLE BLIND, RANDOMISED, CONTROL TRIAL OF A UNANI COMPOUND FORMULATION IN ILTEHAB TAJAWEEFE ANAF MUZMIN
Objective To establish the efficacy and tolerability of Unani formulations both oral as well as inhalation of Kalonji. To provide safe, effective and economical treatment for Iltehab Tajaweefe Anaf Muzmin (Chronic Rhinosinusitis)
Methods A randomized single blind, controlled study of forty patients of CRS. The patients were randomly allocated to two groups each consisting of 20 patients. In Group A, Unani oral formulation of Katan (Linum usitatissimum), Filfil siyah (Piper nigrum) & Honey was given 6gm BD with steam inhalation of Kalonji (Nigella sativa) and Tab Alaspan 1BD with Karvol Plus inhalation was given in Group B.
Results Statistical analysis of the data was done using paired T test by comparing the VAS score of all major and minor symptoms before and after treatment. The result is statistically highly significant in Group A (p <0.0001) and it is significant in group B. (p<0.01).
Conclusion It may be concluded that the Unani formulation with inhalation of Kalonji has statistically highly significant effect on major and minor symptoms of Chronic Rhinosinusitis. A multicentric trial of the test drug on larger sample size for a longer duration is required to establish the efficacy of the formulation on CRS.
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