ANALYSIS OF MEDICINAL PROPERTIES OF VIGNA ACONITIFOLIA (MATKI)
Objective: The seeds and sprouts of matki bean (Vigna aconitifolia), a common food, contain abundant nutrients with biological activities. This work was focused to analyze and compare the medicinal properties of seeds and sprouts of matki beans, with the goal of providing scientific evidence for better application of this commonly used food as a medicine.
Methods: Using Soxhlet apparatus, ethanol extracts of matki bean sprouts and seeds were prepared. Anti-inflammatory activity (inhibition of protein denaturation, inhibition of heat induced hemolysis, and inhibition of protease activity), antioxidant activity, and antihypertensive activity were determined for both sprout and seed extracts.
Results: The anti-inflammatory activity of sprout ethanol extract was found to be highest. Sprout ethanol extract inhibited the activity angiotensin-I-converting enzyme (ACE1) which was maximum as compared to seed extracts. Same was observed for the antioxidant activity, sprout ethanol extract showed higher activity than the seed extract.
Conclusion: The results of the present study will help us to use Vigna aconitifolia as a healthy herbal alternative for the existing chemical remedies for various disorders and rule out the issue of side effects and resistance.
2. Kestwal M, Bagal-Kestwal D, Chiang BH. Analysis and enhancement of nutritional and antioxidant properties of Vigna aconitifolia sprouts. Plant Foods Hum Nutr 2012;67:136-41.
3. Brink M, Jansen PC. Vigna aconitifolia (Jacq.) Maréchal. In: Brink M, Belay G, editors. Plant Resources of Tropical Africa. Wageningen: PROTA Foundation; 2006.
4. Mandal S, Mandal RK. Seed storage proteins and approaches for improvement of their nutritional quality by genetic engineering. Curr Sci 2000;79:576-89.
5. Millerd A. Biochemistry of legume seed proteins. Annu Rev Plant Physiol 1975;26:53-72.
6. Roy F, Boye J, Simpson B. Bioactive proteins and peptides in pulse crops: Pea, chickpea and lentil. Food Res Int 2010;43:432-42.
7. Reshma, Arun KP, Brindha P. In vitro anti-inflammatory, antioxidant and nephroprotective studies on leaves of Aegle marmelos and Ocimum sanctum. Asian J Pharm Clin Res 2014;7:121-9.
8. Jamuna S, Paulsamy S, Karthika K. Screening of in vitro antioxidant activity of methanolic leaf and root extracts of Hypochaeris radicata L. (Asteraceae). J Appl Pharm Sci 2012;2:149-54.
9. Serra CP, Cortes SF, Lombard JA, Braga de Oliveira A, Braga FC. Validation of a colorimetric assay for the in vitro screening of inhibitors of angiotensin-converting enzyme (ACE) from plant extracts. Phytomedicine 2005;12:424-32.
10. Gupta N, Shrivastava N, Singh P, Bhagyawant S. Phytochemical evaluation of moth bean (Vigna aconitifolia L.) seeds and their divergence. Biochem Res Int 2016;2016:3136043.
11. Sreena K, Nair S. Evaluation of anti-inflammatory activity of the plant extract Smithia Sensitiva. Sch Res Libr 2016;8:310-6.
12. Kumar KP, Naik VS, Chandra BV, Lavanya R, Kumar KN, Bhagyasree V, et al. Evaluation of in vitro and in vivo anti-inflammatory activity of aqueous extract of Gliricidia sepium flowers in rats. Int J Pharmacogn Phytochem Res 2014;6:477-81.
13. Rumiyati R, Sudarsono, Susanto BO, Mayasari SK, Wijaya RN. In vitro ACE inhibitory assay of extracts containing flavonoid-phenolic compounds of edible plants. Int J Pharm Clin Res 2016;8:414-8.
14. De Leon R, Torio MA, Manalo M, Aguda R. A Dipeptide with Antihypertensive Activity from Cowpea (Vigna unguiculata) Seed 7S Globulin. Phillipines: National Academy of Science and Technology; 2014. p. 171.
15. Hong F, Ming L, Yi S, Zhanxia L, Yongquan W, Chi L. The antihypertensive effect of peptides: A novel alternative to drugs? Peptides 2008;29:1062-71.
16. Guang C, Phillips R. Plant food-derived angiotensin I converting enzyme inhibitory peptides. J Agric Food Chem 2009;57:5113-20.
17. Wagner H, Elbl G, Lotter H, Guinea M. Evaluation of natural products as inhibitors of angiotensin I-converting enzyme (ACE). Pharm Phamacol Lett 1991;1:15-8.
18. Lacaille-Dubois MA, Franck U, Wagner H. Search for potential angiotensin converting enzyme (ACE)-inhibitors from plants. Phytomedicine 2001;8:47-52.
19. Actis-Goretta L, Ottaviani JI, Keen CL, Fraga CG. Inhibition of angiotensin converting enzyme (ACE) activity by flavan-3-ols and procyanidins. FEBS Lett 2003;555:597-60.
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