COMPARISON OF 1% CHLOROPROCAINE IN SUB-ARACHNOID BLOCK WITH OR WITHOUT FENTANYL FOR ENHANCED RECOVERY AFTER PERIANAL SURGERIES

Authors

  • Tripat Kaur Bindra Department of Anaesthesiology and Intensive Care, GMC and Rajindra Hospital, Patiala, Punjab, India.
  • Davinder Chawla Department of Anaesthesiology and Intensive Care, GMC and Rajindra Hospital, Patiala, Punjab, India.
  • Ashwani Kumar Department of Anaesthesiology and Intensive Care, GMC and Rajindra Hospital, Patiala, Punjab, India.
  • Gurlivleen Kaur Department of Anaesthesiology and Intensive Care, GMC and Rajindra Hospital, Patiala, Punjab, India.
  • Amit Kaur Department of Anaesthesiology and Intensive Care, GMC and Rajindra Hospital, Patiala, Punjab, India.

DOI:

https://doi.org/10.22159/ajpcr.2022.v15i7.44841

Keywords:

1% chloroprocaine, perianal surgery, fentanyl, spinal anesthesia

Abstract

Objective: Spinal anesthesia is a reliable and safe technique for procedures of lower abdomen, perianal surgeries, and lower limbs. The current availability of short acting local anesthetic agents like preservative free 1% chloroprocaine has renewed the interest for this technique in short- and ultra-short procedures. Opioids continue to be the most commonly added adjuvants in local anesthetics for potentiation of analgesic action. In this study, we investigated the effect of intrathecal fentanyl as an adjuvant to 1% chloroprocaine in patients undergoing perianal surgeries.

Methods: This prospective, randomized, and comparative study was conducted in 80 ASA Physical status I and II adult patients (age 20–80 years) undergoing perianal surgeries under spinal anesthesia. Group A patients received 1% chloroprocaine 3 ml (30 mg) and 0.4ml saline and Group B patients received 1% chloroprocaine 3 ml (30 mg) with fentanyl 0.4 ml (20 μg). Primary objectives were duration of analgesia and time to unassisted ambulation. Onset and duration of sensory and motor blockade, maximum height of sensory block, 2 segment regression, hemodynamic parameters, time to voiding, home discharge eligibility, and any side effects were also recorded.

Results: There were no significant differences in demographic characteristics and hemodynamic parameters. The duration of sensory block and duration of analgesia were statistically prolonged in Group B than Group A (p<0.001) without affecting recovery from motor block and time to unassisted ambulation. The adverse effects were comparable in both the groups.

Conclusion: The addition of fentanyl to 1% chloroprocaine intrathecally prolonged the duration of analgesia and sensory block in patients undergoing perianal surgeries.

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Author Biographies

Tripat Kaur Bindra, Department of Anaesthesiology and Intensive Care, GMC and Rajindra Hospital, Patiala, Punjab, India.

Dr. Tripat Kaur Bindra

Professor

Department of Anaesthesiology & Intensive Care,

GMC & Rajindra Hospital, Patiala

 

Davinder Chawla, Department of Anaesthesiology and Intensive Care, GMC and Rajindra Hospital, Patiala, Punjab, India.

Dr. Davinder Chawla

Professor

Department of Anaesthesiology & Intensive Care,

GMC & Rajindra Hospital, Patiala

 

Ashwani Kumar, Department of Anaesthesiology and Intensive Care, GMC and Rajindra Hospital, Patiala, Punjab, India.

Dr. Ashwani Kumar

Professor 

Department of General Surgery,

GMC & Rajindra Hospital, Patiala

 

Gurlivleen Kaur, Department of Anaesthesiology and Intensive Care, GMC and Rajindra Hospital, Patiala, Punjab, India.

Dr. Gurlivleen Kaur

Assistant Professor

Department of Anaesthesiology & Intensive Care,

GMC & Rajindra Hospital, Patiala

 

Amit Kaur, Department of Anaesthesiology and Intensive Care, GMC and Rajindra Hospital, Patiala, Punjab, India.

Dr. Amit Kaur

Anesthesia Resident 

Department of Anaesthesiology & Intensive Care

GMC & Rajindra Hospital, Patiala

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Published

07-07-2022

How to Cite

Tripat Kaur Bindra, Davinder Chawla, Ashwani Kumar, Gurlivleen Kaur, and Amit Kaur. “COMPARISON OF 1% CHLOROPROCAINE IN SUB-ARACHNOID BLOCK WITH OR WITHOUT FENTANYL FOR ENHANCED RECOVERY AFTER PERIANAL SURGERIES”. Asian Journal of Pharmaceutical and Clinical Research, vol. 15, no. 7, July 2022, pp. 131-4, doi:10.22159/ajpcr.2022.v15i7.44841.

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