ASSESSMENT OF IRON PROFILE AND ITS CORRELATION WITH MICRO R% AND OTHER RED CELL PARAMETERS IN PATIENTS WITH CHRONIC RENAL FAILURE ON DIALYSIS AND RECEIVING ERYTHROPOIETIN INJECTION
DOI:
https://doi.org/10.22159/ajpcr.2025v18i1.53474Keywords:
Micro R%, Red cell parameters, Chronic renal failure, Erythropoietin, Iron deficiencyAbstract
Objectives: The objectives of the study are to correlate Micro R% with red cell indices and to assess their efficiency in detecting iron deficiency in chronic kidney disease (CKD) patients receiving erythropoietin (EPO).
Methods: Red cell indices such as mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), MCH concentration, and red cell distribution width generated from automated analyzers frequently help in the diagnosis of iron deficiency. Micro R% is a research-only parameter in an automated analyzer while doing a complete blood count. This study is done to correlate and compare hemoglobin and biochemical parameters in healthy controls and CKD patients and to correlate the Micro R% with MCV and serum iron in detecting iron deficiency in CKD patients receiving EPO.
Results: Red cell indices showed a good correlation with serum iron studies. Micro R% is a reliable parameter for the identification of iron deficiency anemia and it correlates with other red cell indices and with serum iron studies.
Conclusion: Identification of iron deficiency in patients with chronic renal failure on dialysis helps us to start the treatment earlier. Anemia-related complications can be prevented and we can give a better quality of life in these patients.
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