MICROWAVE ASSISTED SYNTHESIS OF NOVEL PYRIMIDINES BEARING BENZENE SULFONAMIDES AND EVALUATION OF ANTICANCER AND ANTIOXIDANT ACTIVITIES

Abstract

A series of some new pyrimidine containing sulfonamides moieties were synthesized via the reaction of chalcones with sulfaguanidine by conventional and microwave oven synthesis. And been evaluated for their anticancer and antioxidant activities. All structures of the compounds were elucidated by elemental analysis and spectral datas.

Keywords: Chalcones, Pyrimidines, Anticancer Activity, Antioxidant Activity.