CYTOTOXICITY OF IONS RELEASED FROM 17-4 PRECIPITATION HARDENING STAINLESS STEEL ORTHODONTIC BRACKETS IN ARTIFICIAL SALIVA


Tjokro Prasetyadi, Bambang Irawan, Miesje Karmiati Purwanegara, Bambang Suharno, Sugeng Supriadi

Abstract


Objective: 17-4 precipitation hardening (PH) stainless steel has a low nickel content, which can reduce the risk of allergic reactions. It also has good mechanical properties against the stress caused by the archwire slot brackets in orthodontic treatments. The main focus of this study to evaluate the metal ions released into artificial saliva from different orthodontic brackets with the same 17-4 PH stainless steel and to examine the in vitro cytotoxicity of the metal.

Methods: Material properties were analyzed by energy dispersive spectroscopy. The 3-(4,5-dimethylthiazol-2-y1)2,5-diphenyltetrazolium bromide (MTT) assay method was used to examine the cytotoxicity of Gemini and Synergy brackets.

Results: The cytotoxicity test on all the orthodontic brackets showed a mean cell viability value above 80% in each immersion group, which means that this material is not cytotoxic to the human immortalized keratinocyte cell line.

Conclusions: The results showed cell viability in the extracts of both groups of brackets, and there was no statistically significant difference between the groups (p>0.05).

Keywords


Cytotoxicity, Corrosion, Nickel, Chrome, Orthodontic brackets.

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References


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About this article

Title

CYTOTOXICITY OF IONS RELEASED FROM 17-4 PRECIPITATION HARDENING STAINLESS STEEL ORTHODONTIC BRACKETS IN ARTIFICIAL SALIVA

Keywords

Cytotoxicity, Corrosion, Nickel, Chrome, Orthodontic brackets.

DOI

10.22159/ijap.2017.v9s2.17

Date

01-01-2018

Additional Links

Manuscript Submission

Journal

International Journal of Applied Pharmaceutics
Vol. 9, Special Issue 2 (Dec.), 2017 Page: 71-73

Online ISSN

0975-7058

Statistics

81 Views | 92 Downloads

Authors & Affiliations

Tjokro Prasetyadi
Ph.D. Program, Faculty of Dentisry, Universitas Indonesia, Jakarta, Indonesia

Bambang Irawan
Department of Dental Materials, Faculty of Dentistry, Universitas Ind onesia, Jakarta, Indonesia

Miesje Karmiati Purwanegara
Department of Orthodontics, Faculty of Dentisry, Universitas Indonesia, Jakarta, Indonesia

Bambang Suharno
Department of Metallurgy and Material Engineering, Faculty of Engineering, Jawa Barat, Universitas Indonesia, Indonesia

Sugeng Supriadi
Department of Mechanical Engineering, Faculty of Engineering, Universitas Indonesia, Jawa Barat, Indonesia
Indonesia


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