THE EFFECTIVENESS OF GIVING SNAIL SLIME (ACATINA FULICA) ON THE HEALING OF POCKET ON THE WISTAR RATS WITH PERIODONTITIS

  • SWASTINI IGAAP Postgraduate Faculty of Medicine Udayana University Bali Indonesia
  • PUTRA MANUABA I. B. Laboratory of Analitic Udayana University Bali Indonesia
  • HASANUDDIN THAHIR Periodontic Department Faculty of Dentistry Hasanudin University Makasar Indonesia
  • RAKA SUDEWI A. A Faculty of Medicine Udayana University Bali Indonesia
  • BAKTA I. MD Faculty of Medicine Udayana University Bali Indonesia
  • MANTIK A. I NYM Faculty of Veterinary Udayana University Bali Indonesia
  • SUKRAMA ID MD Faculty of Veterinary Udayana University Bali Indonesia
  • SUTIRTAYASA IWP Faculty of Veterinary Udayana University Bali Indonesia
  • MAHADEWA TGB Faculty of Medicine Udayana University Bali Indonesia

Abstract

Objective: Periodontitis is an inflammatory disease of dental support tissue caused by certain groups of microorganisms, resulting in progressive destruction of the periodontal ligament and alveolar bone, with pocket formation, recession, or both. Snail slime contains beta-agglutinin (antibody) in plasma (serum), achacin protein, glycoconjugate and sulphate acting, which play a role in the wound healing process by assisting blood clotting process and fibroblast proliferation. This study aims to prove that the provision of snail slime can cure pocket in wistar rats with periodontitis.


Methods: This type of research is an experimental test with pre and post test control group design and involves three treatment groups, each group with five subjects. The first group of debridement, the second group of debridement and orally snail slime and the third group of debridement and topically snail slime, previously rats as subjects were conditioned to periodontitis by the installation of silk ligature in the cervical area of ​​the incisors and injection with actinobacillus actinomycetemcomitans bacteria. The pocket depth is checked with a periodontal probe. Examination on day 11 occurs chronic periodontitis. The eighth day after treatment was examined on the periodontal pocket.


Results: The first group occurred a reduction in pocket depth from 3 mm to 1,00 mm, while in the second group periodontitis healing was characterized by the absence of a pocket, the third group still had pockets with a depth of 0.5 mm. Analysis of significance data using Kruskal-Wallis test, then Mann-Whitney test to know the differences between groups, The average pocket depth in group 1 was 0.00±1.00, while in group 2 was 0.00±0.00, and group 3 was 0.00±0.5 p-value = 0.001 this mean different healing significantly (p<0.05).


Conclusion: Provision of peroral snail slime more quickly cure pocket in wistar rats with periodontitis.

Keywords: Snail slime, Pocket, Periodontitis

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How to Cite
IGAAP, S., PUTRA MANUABA I. B., THAHIR, H., RAKA SUDEWI A. A, BAKTA I. MD, NYM, M. A. I., SUKRAMA ID MD, SUTIRTAYASA IWP, & TGB, M. (2019). THE EFFECTIVENESS OF GIVING SNAIL SLIME (ACATINA FULICA) ON THE HEALING OF POCKET ON THE WISTAR RATS WITH PERIODONTITIS. International Journal of Applied Pharmaceutics, 11(4), 19-21. Retrieved from https://innovareacademics.in/journals/index.php/ijap/article/view/35281
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