ORAL HAIRY LEUKOPLAKIA MANIFESTATIONS RELATED TO CD4 COUNT IN HIV/AIDS PATIENTS AT DR WAHIDIN SUDIROHUSODO HOSPITAL

  • SUMINTARTI Department of Oral Medicine, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
  • MUHAMMAD RUSLIN Departement of Oral and Maxillofacial Surgery, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia
  • A. ST. HAJRAH YUSUF Departement of Oral and Maxillofacial Surgery, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia

Abstract

Objective: The aim of this study to determine the oral hairy leukoplakia manifestations related to CD4 counts in HIV/AIDS patients.


Methods: A cross-sectional study was conducted among 30 patients with HIV/AIDS, who have oral hairy leukoplakia manifestations. Diagnosis of oral hairy leukoplakia (OHL) based on clinical features. CD4 cell counts were obtained from medical records of patients.


Results: The result show that oral hairy leukoplakia related to CD4 cell counts in HIV/AIDS patients had CD4 count<100 cells/mm3 (13.3%) and CD4 counts>100 cells/mm3 (3.3 %).


Conclusion: Oral hairy leukoplakia manifestations in HIV/AIDS patients correlated with low levels CD4 cell counts.

Keywords: Oral hairy leukoplakia, CD4 cell, HIV/AIDS

References

1. Sixbey JW. Epstein barr virus infection. In: Holmeskk, Sparling PF, Stamm WE, Piot P, Wassaerhcit JN, Corey L, et al. editors. Sexually Transmitted Disease. 4th ed. New York: Mc Graw Hill; 2008. p. 453-9.
2. Agbelusi GA, Eweka KA, Umeizudik KA, Okoh M. Oral manifestations of HIV USA: INTECH. Chapter 10; 2013. p. 209-28.
3. Martin LL, Rosseto JHF, Andradl NS, Franco JB, Silva PH, Ortega KL. Diagnosis of oral hairy leukoplakia: the importance of EBV in situ hybridization. Int J Dentist 2017:1-4. https://doi.org/ 10.1155/2017/3457479
4. Kenny SC. Reactivation and lytic replication of EBV. In: Arvin A, Campadellifium G, Mocarski E. Editors. Human Herpes Viruses. Chapter 25. Cambridge: Cambridge University Press; 2007. Available from: http://www.ncbi.nlm.nih.gov/book/ NBK47442.
5. Vaseliv N, Kamird N, Kabal M. Oral manifestations of HIV infection. In: Baylor International Pediatric AIDS Initative. editor HIV Curriculum for The Health Professional Houstan. Texas: USA Baylor Collage of Medicine; 2010. p. 184-93.
6. Sumintarti, Andi RS. Clinical manifestations of oral candidiasis types in AIDS patients at dr wahidin sudirohusodo hospital, makassar. J Dentomaxillofac Sci 2014;13:186-9.
7. Chambers AE, Conn, Pemberton M, Banks R, Sloan P. Twenty fustcentury oral hairy leukoplakia a non HIV associated entity. J Oral Surg Oral Pathol Oral Radol 2015;119:326.
8. Piperi E, Omlie J, Koutlas GL, Pambuccian S. Oral hairy leukoplakia in HIV negative patients: report of 10 cases. Int J Surg Pathol 2010;18:177-83.
9. Regerezi JA, Sciubba JJ, Jordan RC. Oral pathology: correlations san fransisco: Elsevier; 2017. p. 87.
10. Baccoglini L, Atkinson JC, Patton LL, Glick M, Fikarra G, Peterson DE, et al. Managment of viral lesion in HIV-postive patients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;103:S50el-s50e23.
11. Mirna W, Hutapea H. Hubungan jumlah cluster of differentiation 4 (CD4) dengan infeksi oportunistik pada pasien HIV/AIDS di RSUD Dok Jayapura. JBP 2015;7:16-21.
12. Frimpog P, Amponsah EK, Abebrese J, Kim SM. Oral manifestations and their correlation to baseline CD4 count of HIV/AIDS patients in Ghana. Y Korean ASDC Oral Maxillofacial Surg 2017;43:29-36.
13. Nokta M. Oral manifestation associated with HIV infection. Curr HIV/AIDS Rep 2008;5:5-12.
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SUMINTARTI, RUSLIN, M., & YUSUF, A. S. H. (2019). ORAL HAIRY LEUKOPLAKIA MANIFESTATIONS RELATED TO CD4 COUNT IN HIV/AIDS PATIENTS AT DR WAHIDIN SUDIROHUSODO HOSPITAL. International Journal of Applied Pharmaceutics, 11(4), 57-59. https://doi.org/10.22159/ijap.2019.v11s4.35292
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