ANTIBACTERIAL ACTIVITY OF ETHANOLIC EXTRACT BAWANG DAYAK (ELEUTHERINE BULBOSA (MILL.) URB) IN CREAM AGAINST PROPIONIBACTERIUM ACNES

  • SYAHRIDA DIAN ARDHANY Department of Pharmacy Faculty of Health Science, Muhammadiyah University of Palangkaraya, Central Kalimantan, Indonesia
  • SUSI NOVARYATIIN Department of Pharmacy Faculty of Health Science, Muhammadiyah University of Palangkaraya, Central Kalimantan, Indonesia.

Abstract

Objective: The aims of this present study were to formulate antiacne cream consisting ethanolic extract of bawang dayak and evaluate antibacterial
activity of cream on day 0 and day 7 to see stability activity and preparation.
Methods: Cream formula of bawang dayak was evaluated organoleptic characteristics, homogeneity, pH, adhesion test, dispersion test, and in vitro
antibacterial against Propionibacterium acnes.
Results: The results of evaluate cream homogeneity were F3 and F4 on day 7 separate and non-homogen but all formula pH suitable for topical
application. On day 0, F1 and F2 shown antibacterial activity in category weak activity, F3 and F4 in category moderate activity, while on day 7 all
formula have antibacterial activity in category weak activity.
Conclusion: All cream formula potentials inhibit against P. acnes but this research must be improved both of preparation and stability activity.

Keywords: Acne vulgaris, Bawang dayak, Cream, Eleutherine bulbosa, Propionibacterium acnes

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ARDHANY, S. D., & NOVARYATIIN, S. (2019). ANTIBACTERIAL ACTIVITY OF ETHANOLIC EXTRACT BAWANG DAYAK (ELEUTHERINE BULBOSA (MILL.) URB) IN CREAM AGAINST PROPIONIBACTERIUM ACNES. International Journal of Applied Pharmaceutics, 11(5), 1-4. https://doi.org/10.22159/ijap.2019.v11s5.T0020
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