SOMES: A REVIEW ON COMPOSITION, FORMULATION METHODS AND EVALUATIONS OF DIFFERENT TYPES OF “SOMES” DRUG DELIVERY SYSTEM

Authors

  • KUSUMA PRIYA M. D. Department of Pharmaceutics, Centre for Pharmaceutical Nanotechnology, Sri Venkateswara College of Pharmacy, RVS Nagar, Chittoor 517127, Andhra Pradesh, India
  • VINOD KUMAR Department of Pharmaceutics, Centre for Pharmaceutical Nanotechnology, Sri Venkateswara College of Pharmacy, RVS Nagar, Chittoor 517127, Andhra Pradesh, India
  • DAMINI V. K. Department of Pharmaceutics, Centre for Pharmaceutical Nanotechnology, Sri Venkateswara College of Pharmacy, RVS Nagar, Chittoor 517127, Andhra Pradesh, India
  • ESWAR K. Department of Pharmaceutics, Centre for Pharmaceutical Nanotechnology, Sri Venkateswara College of Pharmacy, RVS Nagar, Chittoor 517127, Andhra Pradesh, India
  • KADIRI RAJESH REDDY Department of Pharmaceutics, Mahathi College of Pharmacy, Madanapalle 517319, Andhra Pradesh, India
  • BRITO RAJ S. Department of Pharmaceutics, Centre for Pharmaceutical Nanotechnology, Sri Venkateswara College of Pharmacy, RVS Nagar, Chittoor 517127, Andhra Pradesh, India
  • SUCHARITHA P. Department of Pharmaceutics, Seven Hills College of Pharmacy, Tirupati 517561, Andhra Pradesh, India

DOI:

https://doi.org/10.22159/ijap.2020v12i6.38996

Keywords:

Nanosomes, Drug targeting, Formulation, Surfactants and phospholipids

Abstract

Many drugs are available in the market for several diseases, disorder or even for a condition, but it is difficult to select a suitable carrier to attain maximum bioavailability and potential for a potent drug. Attaining a controlled and sustained release of a drug is purely focused on the selection of a carrier (natural, synthetic and hybrid) like nanosomes. Nanosomes have become a prominent tool in the field of pharmacy. Nanosomes are small uniform structures which deliver the drug to the specific targeted site, which mainly depends upon the presence of ligands, shape, size and surface chemistry. Nanosomes are available in various types which include Niosomes, Liposomes, Electrosomes, Aquasomes, Transfersomes, Phytosomes, Enzymosomes, Ethosomes, Invasome and Sphingosomes. In general, all these nanosomes are quite similar in nature with minute differences in their vesicular characteristics and composition. This review traces various ‘somes’ composition and their role in the formulation, applications, advantages, disadvantages, common formulation procedures and evaluation parameters.

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Published

07-11-2020

How to Cite

M. D., K. P., KUMAR, V., V. K., D., K., E., REDDY, K. R., S., B. R., & P., S. (2020). SOMES: A REVIEW ON COMPOSITION, FORMULATION METHODS AND EVALUATIONS OF DIFFERENT TYPES OF “SOMES” DRUG DELIVERY SYSTEM. International Journal of Applied Pharmaceutics, 12(6), 7–18. https://doi.org/10.22159/ijap.2020v12i6.38996

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Section

Review Article(s)