• SADDAM C. SHAIKH Department of Pharmaceutics (D Pharm), Rajarshi Shahu College of Pharmacy, Buldana, Maharashtra, India 443001,
  • SHWETA G. SABOO Department of Pharmacognosy, Government College of Pharmacy, Karad, Maharashtra, India 415124
  • PRASHANT S. TANDALE Department of Pharmaceutics, School of Pharmaceutical Sciences, Lovely Professional University, Punjab, India 144001
  • FAHIM S. MEMON Department of Pharmaceutics, Rajarshi Shahu College of Pharmacy, Buldana, Maharashtra, India-443001
  • SHARAD D. TAYADE Department of Pharmaceutics (D Pharm), Rajarshi Shahu College of Pharmacy, Buldana, Maharashtra, India 443001
  • M. AKIFUL HAQUE Department of Pharmaceutical Analysis, Anurag University, Venkatapur, Hyderabad, India 500088
  • SHARUK L. KHAN Department of Pharmaceutical Chemistry, MUP's College of Pharmacy (B Pharm), Degaon, Risod, Washim, Maharashtra, India 444504



Quantum dots, Optical properties, Microwave-assisted method, Cytotoxicity, Cell imaging, Sentinel lymph-node mapping


In the twenty-first century, nanotechnology has become cutting-edge technology. It is interdisciplinary and multidisciplinary, covering numerous fields such as medicine, engineering, biology, physics, material sciences, and chemistry. The present work aims to cover the optical properties, method of preparations, surface modifications, bio-conjugation, characterization, stability, and cytotoxicity of quantum dots (QDs).

Articles were reviewed in English literature reporting the pharmaceutical and bio-pharmaceutical aspects of QDs which were indexed in Scopus, web of science, google scholar and PubMed without applying the year of publication criterion.

One significant value of utilizing nanotechnology is that one can alter and control the properties in a genuinely unsurprising way to address explicit applications' issues. In science and biomedicine, the usage of functional nanomaterials has been broadly investigated and has become one of the quick-moving and stimulating research directions. Different types of nanomaterial (silicon nanowires, QDs, carbon nanotubes, nanoparticles of gold/silver) were extensively utilized for biological purposes. Nanomedicine shows numerous advantages in the natural characteristics of targeted drug delivery and therapeutics. For instance, protection of drugs against degradation, improvement in the drug's stability, prolonged circulation time, deceased side effects, and enhanced distribution in tissues. The present review article deals with the quantum dots, their optical properties, method of preparations, surface modifications, bio-conjugation, characterization, stability, and cytotoxicity of quantum dots. The review also discusses various biomedical applications of QDs.

The QDs-based bio-nanotechnology will always be in the growing list of unique applications, with progress being made in specialized nanoparticle development, the detection of elegant conjugation methods, and the discovery of new targeting ligands.


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How to Cite

SHAIKH, S. C., SABOO, S. G., TANDALE, P. S., MEMON, F. S., TAYADE, S. D., HAQUE, M. A., & KHAN, S. L. (2021). PHARMACEUTICAL AND BIOPHARMACEUTICAL ASPECTS OF QUANTUM DOTS-AN OVERVIEW. International Journal of Applied Pharmaceutics, 13(5), 44–53.



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