• Manisha Thapliyal Department of Biotechnology, G. B Pant Engineering College, Pauri Garhwal
  • Anjali Bisht Department of Biotechnology, G. B Pant Engineering College, Pauri Garhwal
  • Ajeet Singh Department of Biotechnology, G. B Pant Engineering College, Pauri Garhwal


Objective: To isolate the antibacterial proteins/peptides from Ficus glomerata leaf.

Methods: Present study was designed to investigate antibacterial activity of proteins/peptides isolated from Ficus glomerata leaf. The isolated proteins/peptides were further checked for antibacterial activity against, Pseudomonas aeruginosa, Bacillus subtilis, Escherichia coli and Salmonella entrica bacterial pathogens.

Results: The results indicates that a 35kDa of protein were identified and exhibit good antibacterial activity against bacterial pathogen among all strains, Salmonella entrica and Pseudomonas aeruginosa exhibit good results with a clear zone of inhibition.

Conclusion: Ficus glomerata is popular for its medicinal properties against therapeutic potential. In the present study a novel protein with broad spectrum antibacterial activity. Microbes cause severe damage to plants which results in a large economic loss so; this protein can be use as an active agent in agriculture for plant protection and also in the development of novel therapeutic agents.
Keywords: Ficus glomerata, SDS-PAGE, Antimicrobial protein (AMPs), Antibacterial protein/peptide


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How to Cite
Thapliyal, M., A. Bisht, and A. Singh. “ISOLATION OF ANTIBACTERIAL PROTEIN/PEPTIDE FROM FICUS GLOMERATA LEAF”. International Journal of Current Pharmaceutical Research, Vol. 8, no. 4, Oct. 2016, pp. 24-27, doi:10.22159/ijcpr.2016v8i4.15271.
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