DEVELOPMENT OF EXTRACTIVE SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF IRON (III) WITH SCHIFF BASE 2-[(2-HYDROXYPHENYLIMINO) METHYL]-4-NITROPHENOL


Datta B. Mandhare, Vasant D. Barhate

Abstract


Objective: A simple spectrophotometric method has been developed for the determination of Iron (III) by using Schiff base 2-[(2-hydroxyphenylimino) methyl]-4-nitrophenol [HPIMNP].

Methods: HPIMNP extracts Fe (III) quantitatively (99.95%) into chloroform from an aqueous solution of pH range 4.0-6.0.

Results: The chloroform extracts show maximum absorption at 510 nm (λ max). Beer’s Law is obeyed over the Fe (III) concentration range of 0.5 to 20.0 µg/ml. The Molar absorptivity and Sandell’s sensitivity for Fe–HPIMNP system is 5000 L mol ˉ1 cmˉ1 and 0.011 µg cmˉ2respectively. The composition of extracted species is found to be 1: 3 [Fe-HPIMNP] by Job’s continuous variation and Mole-ratio method. Interference by various ions has been studied.

Conclusion: The proposed method is rapid, sensitive, reproducible and accurate and it has been satisfactory applied for the determination of Iron in Pharmaceutical Samples.


Keywords


Solvent Extraction, Extractive Spectrophotometry, Iron (III), Schiff base, 2-[(2-hydroxyphenylimino) methyl]-4-nitrophenol [HPIMNP], Pharmaceutical sample.

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References


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About this article

Title

DEVELOPMENT OF EXTRACTIVE SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF IRON (III) WITH SCHIFF BASE 2-[(2-HYDROXYPHENYLIMINO) METHYL]-4-NITROPHENOL

Keywords

Solvent Extraction, Extractive Spectrophotometry, Iron (III), Schiff base, 2-[(2-hydroxyphenylimino) methyl]-4-nitrophenol [HPIMNP], Pharmaceutical sample.

DOI

10.22159/ijcpr.2016v8i4.15924

Date

18-10-2016

Additional Links

Manuscript Submission

Journal

International Journal of Current Pharmaceutical Research
Vol 8, Issue 4, 2016 Page: 89-91

Online ISSN

0975-7066

Statistics

43 Views | 135 Downloads

Authors & Affiliations

Datta B. Mandhare
V. E. S. College of Art, Science and Commerce, Sindhi Society Chembur, Mumbai 400071, India

Vasant D. Barhate
V. E. S. College of Art, Science and Commerce, Sindhi Society Chembur, Mumbai 400071, India


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