DEVELOPMENT OF EXTRACTIVE SPECTROPHOTOMETRIC METHOD FOR THE DETERMINATION OF IRON (III) WITH SCHIFF BASE 2-[(2-HYDROXYPHENYLIMINO) METHYL]-4-NITROPHENOL
Objective: A simple spectrophotometric method has been developed for the determination of Iron (III) by using Schiff base 2-[(2-hydroxyphenylimino) methyl]-4-nitrophenol [HPIMNP].
Methods: HPIMNP extracts Fe (III) quantitatively (99.95%) into chloroform from an aqueous solution of pH range 4.0-6.0.
Results: The chloroform extracts show maximum absorption at 510 nm (Î» max). Beer's Law is obeyed over the Fe (III) concentration range of 0.5 to 20.0 Âµg/ml. The Molar absorptivity and Sandell's sensitivity for Feâ€“HPIMNP system is 5000 L mol Ë‰1 cmË‰1 and 0.011 Âµg cmË‰2respectively. The composition of extracted species is found to be 1: 3 [Fe-HPIMNP] by Job's continuous variation and Mole-ratio method. Interference by various ions has been studied.
Conclusion: The proposed method is rapid, sensitive, reproducible and accurate and it has been satisfactory applied for the determination of Iron in Pharmaceutical Samples.
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