• Swapnil S. Bornare Department of Quality Assurance Techniques, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik 422213, Maharashtra, India
  • Smita S. Aher Department of Quality Assurance Techniques, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik 422213, Maharashtra, India
  • Ravindranath B. Saudagar Department of Quality Assurance Techniques, R. G. Sapkal College of Pharmacy, Anjaneri, Nashik 422213, Maharashtra, India




Film forming gels, Transdermal drug delivery, Gelling agents


Film forming gels are a novel approach in this area that might present an alternative to the conventional dosage forms used on the skin, such as ointments, creams, gels or patches. The polymeric solution is applied to the skin as a liquid and forms an almost invisible film in situ by solvent evaporation. Transdermal drug delivery system (TDDS) and dermal drug delivery system can provide some desirable performances over conventional pharmaceutical dosage formulations, such as avoiding gut and hepatic first-pass metabolism, improving drug bioavailability, reducing dose frequency and stabilizing drug delivery profiles. The aim of this review was to search for alternatives to the conventional forms in order to reduce skin irritation, improve skin adhesion properties, enhance the drug release and increase the patient acceptability from an aesthetic perspective. Because of their peculiar rheological behaviour, polymeric gels are beneficial in terms of ease of preparation, ease of application, adhesion to the application surface and ability to deliver a wide variety of drugs.


Download data is not yet available.


Renata CV, Tatiele K, Silvia GS. Drug transport across skin. In: Muro S. editor. Drug Delivery across Physiological Barriers. Taylor and Francis Group LLC; 2016. p. 132–4.

Sharma N, Agarwal G, Rana A. A review: transdermal drug delivery system a tool for novel drug delivery system. Int J Drug Dev Res 2011;3:70–84.

Michaels AS, Chandrasekaran SK, Shaw JE. Drug permeation through human skin: theory and in vitro experimental measurement. AIChE J 1975;21:985–96.

Prausnitz MR, Langer R. Transdermal drug delivery. Nat Biotechnol 2008;26:1261–8.

Dhiman S, Singh GT, Rehni AK. Transdermal patches: a recent approach to new drug delivery system. Int J Pharm Pharm Sci 2011;3:26–34.

Advanced Film-Forming Agent for Transdermal Drug Delivery. Available from: http://marketplace.yet2.com/app/insight/ techofweek/28842?Sid=350. [Last accessed on 12 Dec 2016]

Fungal Infections of the Skin. Available from: http://www.webmd.com/skin-problems-and-treatments/guide/fungal-infections-skin#1. [Last accessed on 24 Dec 2016].

Devaux S, Castela A, Archier E. Adherence to topical treatment in psoriasis: a systematic literature review. J Eur Acad Dermatol Venereol 2012;26:61–7.

Tan X, Feldman SR, Chang J. Topical drug delivery systems in dermatology: a review of patient adherence issues. Expert Opin Drug Delivery 2012;9:1263–71.

Mcauley WJ, Caserta F, Hoboken NJ. Film-forming and heated systems. In: Donnelly RF, Singh TRR. editors. Novel delivery systems for transdermal and intradermal drug delivery. United States: John Wiley and Sons; 2015. p. 97–107.

Frederiksen K, Guy RH, Petersson K. The potential of polymeric ï¬lm-forming systems as sustained delivery platforms for topical drugs. Expert Opin Drug Delivery 2015; 13:349–60.

Brown MB, Jones SA, Limited M. Topical ï¬lm-forming monophasic formulations. Patent CA2622624C; 2006.

Zurdo Schroeder I. Film forming polymeric solutions as drugdelivery systems for the skin, Saarland University, Saarbrücken, Germany; 2007. [Last accessed on 21 Dec 2016].

Naik A, Kalia YN, Guy RH. Transdermal drug delivery: overcoming the skin's barrier function. Pharm Sci Technol 2000;3:318-26.

Thomas BJ, Finnin BC. The transdermal revolution. Drug Discovery Today 2004;16:697-703.

Zhai H, Maibach HI. Occlusion vs. skin barrier function. Skin Res Technol 2002;8:1-6.

Alberti I, Grenier A, Kraus, Raus H, Carrara DN. Pharmaceutical development and clinical effectiveness of a novel gel technology for transdermal drug delivery. Exp Opin Drug Delivery 2005;2:935-50.

Lee JW, Park JH, Robinson JR. Bioadhesive-based dosage forms: the next generation. J Pharmaceutical Sci 2000;89:850-66.



How to Cite

Bornare, S. S., S. S. Aher, and R. B. Saudagar. “A REVIEW: FILM FORMING GEL NOVEL DRUG DELIVERY SYSTEM”. International Journal of Current Pharmaceutical Research, vol. 10, no. 2, Mar. 2018, pp. 25-28, doi:10.22159/ijcpr.2018v10i2.25886.



Review Article(s)

Most read articles by the same author(s)