PSYCHOPHARMACOLOGICAL SCREENING OF ETHANOLIC EXTRACT OF LANATA CANARA LINN SEEDS

Authors

  • RESHMA Department of Pharmacology, Smt. Sarojini Ramulamma College of Pharmacy, Mahabubnagar 509001
  • SANA BUTOOL Department of Pharmacology, Smt. Sarojini Ramulamma College of Pharmacy, Mahabubnagar 509001
  • MD FAHEEMUDDIN Department of Pharmacology, Smt. Sarojini Ramulamma College of Pharmacy, Mahabubnagar 509001
  • ASIYA KHATOON Department of Pharmacology, Smt. Sarojini Ramulamma College of Pharmacy, Mahabubnagar 509001
  • ISHRATH FATIMA Department of Pharmacology, Smt. Sarojini Ramulamma College of Pharmacy, Mahabubnagar 509001

DOI:

https://doi.org/10.22159/ijcpr.2022v14i3.1962

Keywords:

Lantana camara, Actophotometer, Elevated plus maze, Y maze, Rota rod, Soxhlet apparatus, Antianxiety activity, Anti psychotic activity, Muscle relaxant activity

Abstract

Objective: To study the skeletal muscle relaxant, antipsychotic and anti anxiety activity of ethanolic extract of Lantana camaralinn seeds in male wistar albino mice.

Methods: The extract of the seeds of Lantana camaralinn was prepared by using Soxhlet extraction and the obtained extract is used for the evaluation of antianxiety activity, antipsychotic activity and muscle relaxant activity using male albino wistar mice.

Results: The results showed that the high dose (400 mg/kg) of the extract has shown significant anti anxiety, anti psychotic and skeletal muscle relaxant activities than the low dose (200 mg/kg).

Conclusion: we concluded that the plant Lantana camaralinn seeds has significant skeletal muscle relaxant, anti anxiety and anti psychotic activities as evidenced by the Rota rod, elevated plus maze, Y maze and acto photometer.

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Published

15-05-2022

How to Cite

RESHMA, S. BUTOOL, M. FAHEEMUDDIN, A. KHATOON, and I. FATIMA. “PSYCHOPHARMACOLOGICAL SCREENING OF ETHANOLIC EXTRACT OF LANATA CANARA LINN SEEDS”. International Journal of Current Pharmaceutical Research, vol. 14, no. 3, May 2022, pp. 28-32, doi:10.22159/ijcpr.2022v14i3.1962.

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