Comparative antibacterial and antifungal activities of benzene extract of three medicinal plants

Authors

  • Sasikala rp
  • Sangeetha K
  • Meena Ks

Abstract

Objective: This study was carried out with an objective to investigate the antibacterial and antifungal potential of three Indian medicinal plants.

Methods: Antimicrobial activity of benzene extracts of three plants namely Abutilon indicum, Plectranthus amboinicus, Aegle marmelos were determined using agar disc diffusion method at different concentration from 5-30 μg/μl against two gram positive Staphylococcus aureus, Enterococcus faecalis and two fungal strains Aspergillus niger, Aspergillus fumigatus and compared with standard drugs Norfloxacin & Fluconazole respectively.

Results: Benzene extract of fruits from Abutilon indicum inhibited Staphylococcus aureus, Enterococcus faecalis at 30 μg/μl and leaves of Plectranthus amboinicus showed considerable inhibiting activity against the Aspergillus niger, Aspergillus fumigatus at 30 μg/μl.

Conclusion: Hence, these plants can be further used to determine the bioactive natural products that may provide as leads in the development of new drugs.

References

Javed Ahmad1 and Iffat Khan2, Antioxidant Potential of Abutilon indicum (L.) Sw. J Plant Pathol Microb, 2012, 3:3.

Shilpi Arora, Devendra Pratap Singh, Ankit Saini, Ashish Kumar Pharmacognostic Investigation On Roots & Leaves Extract Of Abutilon Indicum Linn. International Journal of Research and Development in Pharmacy and Life Sciences, 2013, 2( 5): 567-573.

Rajurkar R, Jain R, Matake N, Aswar P, Khadbadi SS. Antiinflammatory action of Abutilon indicum (L.) sweet leaves by HRBC membrane stablisation. Res J Pharm Techn. 2009,2:415–6.

Razia M, Rajalakshmi BS, lavanya K, Karthiga V, Bernala W, Deboral P GCMS, FTIR and Invitro antibacterial activity of Abutilon indicum. Int J Biol Pharm Res. 2012,4:3959–65.

Samy PR, Thwin MM, Gopalakrishnakone P, Ignacimuthu S. Ethnobotanical Survey of folk plants for the treatment of snakebites in Southern part of Tamilnadu, India. Journal of Ethnopharmacology, 2008, 115: 302-312.

Ignacimuthu S, Ayyanar M, Sakarasivaraman K. Ethnobotanical study of medicinal plants used by Paliyar tribals in Theni district of Tamil Nadu, India. Fitoterapia 2008, 79:562-568.

Ali ZA. Folk veterinary medicine in Moradabad District (Uttar Pradesh), India. Fitoterapia 1999, 70: 340-347.

Mohite M. S., Shelar P. A., Raje V. N., Babar S. J., Sapkal R. K. Review on Pharmacological Properties of Abutilon indicum, Asian J. Pharm. Res, 2012,2 (4):156-160

Khadabadi SS and Bhajipale NS, A Review on Some Important Medicinal Plants of Abutilon spp. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 2010, 1(4): 718.

Tripathi P, Chauhan NS, Patel JR, Anti-inflammatory activity of Abutilon indicum extract. Nat Prod Res. 2012, 26(17):1659-61

Indira Priya Darsini A & S Shamshad, Antimicrobial activity and priliminary phytochemical screening of abutilon indicum, International Journal of Pharmacy and Biological Sciences, 2015, 5(2), 06-10.

Kaladhar DSVGK, Swathi Saranya K , Varahalarao Vadlapudi and Nagendra Sastry Yarla, Evaluation of Anti-inflammatory and Anti-proliferative Activity of Abutilon indicum L. Plant Ethanolic Leaf Extract on Lung Cancer Cell Line A549 for System Network Studies, J Cancer Sci Ther 2014, 6:6.

Kousalya. M, Kokila. N, Sudha. K.M, Kalaiselvi .B, In Vitro Anti inflammatory Activity of Abutilon Indicum Root, International Journal Of Frontiers In Science And Technology, 2013, 1(4), 63-73.

V.Gnanavel And A. Mary Saral, Gc-Ms Analysis Of Petroleum Ether And Ethanol Leaf Extracts From Abrus Precatorius Linn., Int J Pharm Bio Sci , 2013 ,4(3): 37 – 44.

Patel axay R, Garach dipak, Aegle marmelos(Linn): A therapeutic boon for human health, International Journal of Research in Ayurveda and Pharmacy,2012, 3(2).

Balakumar S, Rajan S , Thirunalasundari T, Jeeva S4 Antifungal activity of Aegle marmelos (L.) Correa (Rutaceae) leaf extract on dermatophytes, Asian Pac J Trop Biomed 2011; 1(4): 309-312

V. Mohan, A. G. Molly, and A. N. Eldo, Aegle marmelos extract as a potent bactericide,†Asian Journal of Microbiology, Biotechnology and Environmental Sciences, 2005, 7(4), 639–644.

D. Supriya, S. Ashish, S. Ankit, G. Nirmala, and R. C. Agrawal, Evaluation of in vitro antibacterial potential of ripe fruits of Aegle marmelos,†International Journal of Pharmacy and Pharmaceutical Sciences, 2012, 4 (3), 179–181.

L. L. Zaika, Spices and herbs: their antimicrobial activity and its determination,†Journal of Food Safety, 1988, 9 (2), 97–118.

K. Suresh, P. K. Senthilkumar, and B. Karthikeyan, Antimicrobial activity of Aegle marmelos against clinical pathogens,â€Journal of Phytology, 2009, 1(5), 323–327.

G. Yismaw, B. Tessema, A. Mulu, and M. Tiruneh, The invitro assessment of antibacterial effect of papaya seed extract against bacterial pathogens isolated from urine, wound and stool,†Ethiopian Medical Journal,2008, 46(1),71–77.

Bhatt, P. and Negi, P. S, Antioxidant and antibacterial activities in the leaf extracts of Indian borage (Plectranthus ambionicus). Food and Nutrition Sciences, 2012, 3: 146-152

Gurgel, A. P. A. D., da Silva, J. G., Grangiero, A. R. S., Danielli, Oliveira, D. C., Lima, C. M. P., da Silva, A. C. P., Oliveira, R. A. G. and Souza, I. A. In vivo study of the anti-inflammatory and antitumor activities of leaves from Plectranthus amboinicus (Lour.) Spreng (Lamiaceae). Journal of Ethnopharmacology, 2009, 125: 361-363 .

Lukhoba, C. W., Simmonds, M. S. J. and Paton, A. J. Plectranthus: A review of ethnobotanical uses. Journal of Ethnopharmacology, 2006 103: 1-24.

Manjamalai, A., Alexander, T. and Berlin Grace, V. M. Bioactive evaluation of the essential oil of Plectranthus amboinicus by GC-MS analysis and its role as a drug for microbial infections and inflammation. International Journal of Pharmacy and Pharmaceutical Sciences, 2012, 4 (3): 205 – 211.

Murthy, P. S., Ramalakshmi, K. and Srinivas, P. Fungitoxic activity if Indian borage (Plectranthus amboinicus) volatiles. Food Chemistry, 2009, 114: 1014 – 1018.

Published

01-07-2017

How to Cite

rp, S., K, S., & Ks, M. (2017). Comparative antibacterial and antifungal activities of benzene extract of three medicinal plants. Innovare Journal of Life Sciences, 5(3), 3–5. Retrieved from https://innovareacademics.in/journals/index.php/ijls/article/view/18224

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