STROKE OUTCOMES IN NON-DIABETIC, DENOVO DIABETIC AND DIABETIC INDIAN PATIENTS MEASURED BY MODIFIED RANKIN SCALE: AN OBSERVATIONAL STUDY


Syed Junaid Ahmed, Abdur Rahman Mohd Masood, Safiya Sumana, Khadeer Ahmed Ghori, Javed Akhtar Ansari, Musa Khan

Abstract


Objective: Hyperglycemia is a known risk factor which adversely impacts the outcomes in stroke patients compared to patients with normal blood glucose levels. Patients suffering from an acute stroke who are previously nonhyperglycemic may show elevated blood glucose levels. The present study was designed to measure the outcomes in denovo diabetic and diabetic stroke patients compared to nondiabetics.

Methods: A prospective observational study over a period of 6 mo, in which 103 patients were divided into three cohorts based on their blood glucose levels (nondiabetic, denovo diabetic and diabetics). The modified Rankin scale (mRS) score was calculated at in-hospital admission and discharge in these three cohorts. The initial and final scores were correlated and mean differences with respect to outcomes between all the three cohorts was calculated.

Results: The mean mRS at the time of hospital admission in diabetics and nondiabetics was 3.6±0.81 and 3.3±0.78 which decreased to 2.8±0.95 and 2.9±0.83 respectively at the time of discharge. The mean mRS score in denovo diabetic stroke patients during in-hospital admission was 4±0.81 which was calculated as 3.7±0.85 at the time of discharge. The mean difference in mRS score in diabetics vs non-diabetics was found to be 0.73±0.8 (p =<0.001). The mean difference in mRS score of denovo diabetics vs non-diabetics and denovo diabetics vs diabetics was 0.30±0.63 and 0.38±0.61 respectively (p = 0.1).

Conclusion: Results of these observational study in Indian patients, highlights the need for controlling hyperglycemia in stroke patients to improve outcomes and to prevent mortality arising out of acute stroke attacks.


Keywords


Stroke, Hyperglycemia, Denovo diabetes, Modified Rankin scale, Outcomes

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About this article

Title

STROKE OUTCOMES IN NON-DIABETIC, DENOVO DIABETIC AND DIABETIC INDIAN PATIENTS MEASURED BY MODIFIED RANKIN SCALE: AN OBSERVATIONAL STUDY

Keywords

Stroke, Hyperglycemia, Denovo diabetes, Modified Rankin scale, Outcomes

DOI

10.22159/ijpps.2017v9i8.18378

Date

01-08-2017

Additional Links

Manuscript Submission

Journal

International Journal of Pharmacy and Pharmaceutical Sciences
Vol 9, Issue 8, 2017 Page: 94-97

Online ISSN

0975-1491

Statistics

226 Views | 71 Downloads

Authors & Affiliations

Syed Junaid Ahmed
Department of Pharmacy Practice and PharmD, MESCO College of Pharmacy, Osmania University, Hyderabad, Telangana.
India

Abdur Rahman Mohd Masood
Department of Pharmacy Practice and PharmD, MESCO College of Pharmacy, Osmania University, Hyderabad, Telangana.
India

Safiya Sumana
Department of Pharmacy Practice and PharmD, MESCO College of Pharmacy, Osmania University, Hyderabad, Telangana.
India

Khadeer Ahmed Ghori
Department of Pharmacy Practice and PharmD, MESCO College of Pharmacy, Osmania University, Hyderabad, Telangana.
India

Javed Akhtar Ansari
Department of Pharmacy Practice and PharmD, MESCO College of Pharmacy, Osmania University, Hyderabad, Telangana.
India

Musa Khan
Department of General Medicine, Osmania General Hospital, Hyderabad, Telangana.
India


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